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Erschienen in: Intensive Care Medicine 9/2011

01.09.2011 | Original

The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks

verfasst von: Nicolò Patroniti, Alberto Zangrillo, Federico Pappalardo, Adriano Peris, Giovanni Cianchi, Antonio Braschi, Giorgio A. Iotti, Antonio Arcadipane, Giovanna Panarello, V. Marco Ranieri, Pierpaolo Terragni, Massimo Antonelli, Luciano Gattinoni, Fabrizio Oleari, Antonio Pesenti

Erschienen in: Intensive Care Medicine | Ausgabe 9/2011

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Abstract

Purpose

In view of the expected 2009 influenza A(H1N1) pandemic, the Italian Health Authorities set up a national referral network of selected intensive care units (ICU) able to provide advanced respiratory care up to extracorporeal membrane oxygenation (ECMO) for patients with acute respiratory distress syndrome (ARDS). We describe the organization and results of the network, known as ECMOnet.

Methods

The network consisted of 14 ICUs with ECMO capability and a national call center. The network was set up to centralize all severe patients to the ECMOnet centers assuring safe transfer. An ad hoc committee defined criteria for both patient transfer and ECMO institutions.

Results

Between August 2009 and March 2010, 153 critically ill patients (53% referred from other hospitals) were admitted to the ECMOnet ICU with suspected H1N1. Sixty patients (48 of the referred patients, 49 with confirmed H1N1 diagnosis) received ECMO according to ECMOnet criteria. All referred patients were successfully transferred to the ECMOnet centers; 28 were transferred while on ECMO. Survival to hospital discharge in patients receiving ECMO was 68%. Survival of patients receiving ECMO within 7 days from the onset of mechanical ventilation was 77%. The length of mechanical ventilation prior to ECMO was an independent predictor of mortality.

Conclusions

A network organization based on preemptive patient centralization allowed a high survival rate and provided effective and safe referral of patients with severe H1N1-suspected ARDS.
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Metadaten
Titel
The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks
verfasst von
Nicolò Patroniti
Alberto Zangrillo
Federico Pappalardo
Adriano Peris
Giovanni Cianchi
Antonio Braschi
Giorgio A. Iotti
Antonio Arcadipane
Giovanna Panarello
V. Marco Ranieri
Pierpaolo Terragni
Massimo Antonelli
Luciano Gattinoni
Fabrizio Oleari
Antonio Pesenti
Publikationsdatum
01.09.2011
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 9/2011
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-011-2301-6

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