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Erschienen in: Intensive Care Medicine 8/2012

01.08.2012 | Original

Ordering CT pulmonary angiography to exclude pulmonary embolism: defense versus evidence in the emergency room

verfasst von: Martin Rohacek, Janet Buatsi, Zsolt Szucs-Farkas, Birgit Kleim, Heinz Zimmermann, Aristomenis Exadaktylos, Christoforos Stoupis

Erschienen in: Intensive Care Medicine | Ausgabe 8/2012

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Abstract

Purpose

To identify reasons for ordering computed tomography pulmonary angiography (CTPA), to identify the frequency of reasons for CTPA reflecting defensive behavior and evidence-based behavior, and to identify the impact of defensive medicine and of training about diagnosing pulmonary embolism (PE) on positive results of CTPA.

Methods

Physicians in the emergency department of a tertiary care hospital completed a questionnaire before CTPA after being trained about diagnosing PE and completing questionnaires.

Results

Nine hundred patients received a CTPA during 3 years. For 328 CTPAs performed during the 1-year study period, 140 (43 %) questionnaires were completed. The most frequent reasons for ordering a CTPA were to confirm/rule out PE (93 %), elevated D-dimers (66 %), fear of missing PE (55 %), and Wells/simplified revised Geneva score (53 %). A positive answer for “fear of missing PE” was inversely associated with positive CTPA (OR 0.36, 95 % CI 0.14–0.92, p = 0.033), and “Wells/simplified revised Geneva score” was associated with positive CTPA (OR 3.28, 95 % CI 1.24–8.68, p = 0.017). The proportion of positive CTPA was higher if a questionnaire was completed, compared to the 2-year comparison period (26.4 vs. 14.5 %, OR 2.12, 95 % CI 1.36–3.29, p < 0.001). The proportion of positive CTPA was non-significantly higher during the study period than during the comparison period (19.2 vs. 14.5 %, OR 1.40, 95 % CI 0.98–2.0, p = 0.067).

Conclusion

Reasons for CTPA reflecting defensive behavior—such as “fear of missing PE”—were frequent, and were associated with a decreased odds of positive CTPA. Defensive behavior might be modifiable by training in using guidelines.
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Literatur
1.
Zurück zum Zitat Oger E (2000) Incidence of venous thromboembolism: a community-based study in Western France. EPI-GETBP Study Group. Groupe d’Etude de la Thrombose de Bretagne Occidentale. Thromb Haemost 83:657–660PubMed Oger E (2000) Incidence of venous thromboembolism: a community-based study in Western France. EPI-GETBP Study Group. Groupe d’Etude de la Thrombose de Bretagne Occidentale. Thromb Haemost 83:657–660PubMed
2.
Zurück zum Zitat Spencer FA, Emery C, Lessard D, Anderson F, Emani S, Aragam J, Becker RC, Goldberg RJ (2006) The Worcester venous thromboembolism study: a population-based study of the clinical epidemiology of venous thromboembolism. J Gen Intern Med 21:722–727PubMedCrossRef Spencer FA, Emery C, Lessard D, Anderson F, Emani S, Aragam J, Becker RC, Goldberg RJ (2006) The Worcester venous thromboembolism study: a population-based study of the clinical epidemiology of venous thromboembolism. J Gen Intern Med 21:722–727PubMedCrossRef
3.
Zurück zum Zitat Goldhaber SZ, Visani L, De Rosa M (1999) Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet 353:1386–1389PubMedCrossRef Goldhaber SZ, Visani L, De Rosa M (1999) Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet 353:1386–1389PubMedCrossRef
5.
Zurück zum Zitat Wells PS, Anderson DR, Rodger M, Ginsberg JS, Kearon C, Gent M, Turpie AG, Bormanis J, Weitz J, Chamberlain M, Bowie D, Barnes D, Hirsh J (2000) Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost 83:416–420PubMed Wells PS, Anderson DR, Rodger M, Ginsberg JS, Kearon C, Gent M, Turpie AG, Bormanis J, Weitz J, Chamberlain M, Bowie D, Barnes D, Hirsh J (2000) Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost 83:416–420PubMed
6.
Zurück zum Zitat Klok FA, Mos IC, Nijkeuter M, Righini M, Perrier A, Le Gal G, Huisman MV (2008) Simplification of the revised Geneva score for assessing clinical probability of pulmonary embolism. Arch Intern Med 168:2131–2136PubMedCrossRef Klok FA, Mos IC, Nijkeuter M, Righini M, Perrier A, Le Gal G, Huisman MV (2008) Simplification of the revised Geneva score for assessing clinical probability of pulmonary embolism. Arch Intern Med 168:2131–2136PubMedCrossRef
7.
Zurück zum Zitat Hermer LD, Brody H (2010) Defensive medicine, cost containment, and reform. J Gen Intern Med 25:470–473PubMedCrossRef Hermer LD, Brody H (2010) Defensive medicine, cost containment, and reform. J Gen Intern Med 25:470–473PubMedCrossRef
8.
Zurück zum Zitat Studdert DM, Mello MM, Sage WM, DesRoches CM, Peugh J, Zapert K, Brennan TA (2005) Defensive medicine among high-risk specialist physicians in a volatile malpractice environment. JAMA 293:2609–2617PubMedCrossRef Studdert DM, Mello MM, Sage WM, DesRoches CM, Peugh J, Zapert K, Brennan TA (2005) Defensive medicine among high-risk specialist physicians in a volatile malpractice environment. JAMA 293:2609–2617PubMedCrossRef
9.
Zurück zum Zitat Khemani RG, Sward K, Morris A, Dean JM, Newth CJ (2011) Variability in usual care mechanical ventilation for pediatric acute lung injury: the potential benefit of a lung protective computer protocol. Intensive Care Med 37:1840–1848PubMedCrossRef Khemani RG, Sward K, Morris A, Dean JM, Newth CJ (2011) Variability in usual care mechanical ventilation for pediatric acute lung injury: the potential benefit of a lung protective computer protocol. Intensive Care Med 37:1840–1848PubMedCrossRef
10.
Zurück zum Zitat Jena AB, Seabury S, Lakdawalla D, Chandra A (2011) Malpractice risk according to physician specialty. N Engl J Med 365:629–636PubMedCrossRef Jena AB, Seabury S, Lakdawalla D, Chandra A (2011) Malpractice risk according to physician specialty. N Engl J Med 365:629–636PubMedCrossRef
11.
Zurück zum Zitat Di Nisio M, Squizzato A, Rutjes AW, Buller HR, Zwinderman AH, Bossuyt PM (2007) Diagnostic accuracy of D-dimer test for exclusion of venous thromboembolism: a systematic review. J Thromb Haemost 5:296–304PubMedCrossRef Di Nisio M, Squizzato A, Rutjes AW, Buller HR, Zwinderman AH, Bossuyt PM (2007) Diagnostic accuracy of D-dimer test for exclusion of venous thromboembolism: a systematic review. J Thromb Haemost 5:296–304PubMedCrossRef
12.
Zurück zum Zitat Carrier M, Righini M, Djurabi RK, Huisman MV, Perrier A, Wells PS, Rodger M, Wuillemin WA, Le Gal G (2009) VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonary embolism. A systematic review of management outcome studies. Thromb Haemost 101:886–892PubMed Carrier M, Righini M, Djurabi RK, Huisman MV, Perrier A, Wells PS, Rodger M, Wuillemin WA, Le Gal G (2009) VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonary embolism. A systematic review of management outcome studies. Thromb Haemost 101:886–892PubMed
13.
Zurück zum Zitat Eagles D, Stiell IG, Clement CM, Brehaut J, Taljaard M, Kelly AM, Mason S, Kellermann A, Perry JJ (2008) International survey of emergency physicians’ awareness and use of the Canadian cervical-spine rule and the Canadian computed tomography head rule. Acad Emerg Med 15:1256–1261PubMedCrossRef Eagles D, Stiell IG, Clement CM, Brehaut J, Taljaard M, Kelly AM, Mason S, Kellermann A, Perry JJ (2008) International survey of emergency physicians’ awareness and use of the Canadian cervical-spine rule and the Canadian computed tomography head rule. Acad Emerg Med 15:1256–1261PubMedCrossRef
14.
15.
Zurück zum Zitat Boehnert MU, Zimmermann H, Exadaktylos AK (2009) O knowledge, where art thou? Evidence and suspected appendicitis. J Eval Clin Pract 15:1177–1179PubMedCrossRef Boehnert MU, Zimmermann H, Exadaktylos AK (2009) O knowledge, where art thou? Evidence and suspected appendicitis. J Eval Clin Pract 15:1177–1179PubMedCrossRef
16.
Zurück zum Zitat Katz DA, Williams GC, Brown RL, Aufderheide TP, Bogner M, Rahko PS, Selker HP (2005) Emergency physicians’ fear of malpractice in evaluating patients with possible acute cardiac ischemia. Ann Emerg Med 46:525–533PubMedCrossRef Katz DA, Williams GC, Brown RL, Aufderheide TP, Bogner M, Rahko PS, Selker HP (2005) Emergency physicians’ fear of malpractice in evaluating patients with possible acute cardiac ischemia. Ann Emerg Med 46:525–533PubMedCrossRef
17.
18.
Zurück zum Zitat Mello MM, Chandra A, Gawande AA, Studdert DM (2010) National costs of the medical liability system. Health Aff (Millwood) 29:1569–1577CrossRef Mello MM, Chandra A, Gawande AA, Studdert DM (2010) National costs of the medical liability system. Health Aff (Millwood) 29:1569–1577CrossRef
20.
Zurück zum Zitat Asch DA, Jedrziewski MK, Christakis NA (1997) Response rates to mail surveys published in medical journals. J Clin Epidemiol 50:1129–1136PubMedCrossRef Asch DA, Jedrziewski MK, Christakis NA (1997) Response rates to mail surveys published in medical journals. J Clin Epidemiol 50:1129–1136PubMedCrossRef
Metadaten
Titel
Ordering CT pulmonary angiography to exclude pulmonary embolism: defense versus evidence in the emergency room
verfasst von
Martin Rohacek
Janet Buatsi
Zsolt Szucs-Farkas
Birgit Kleim
Heinz Zimmermann
Aristomenis Exadaktylos
Christoforos Stoupis
Publikationsdatum
01.08.2012
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 8/2012
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-012-2595-z

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