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Erschienen in: Intensive Care Medicine 5/2013

01.05.2013 | Editorial

From protective ventilation to super-protective ventilation for acute respiratory distress syndrome

verfasst von: Marcus J. Schultz, Nicole P. Juffermans, Michael A. Matthay

Erschienen in: Intensive Care Medicine | Ausgabe 5/2013

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Excerpt

For a long time, critical care physicians understood that positive pressure mechanical ventilation was a life-saving strategy in patients with acute respiratory failure, especially in patients with acute respiratory distress syndrome, originally described in 1967 [1]. However, the harmful effects of the traditional use of higher tidal volumes and higher airway pressures were not recognized until more than 30 years later when the beneficial effects of ventilation with a lower tidal volume (6 ml/kg predicted body weight, PBW) and a plateau airway pressure <30 cmH2O were established in the landmark NHLBI ARDS Network trial in 2000 [2]. Some clinicians and investigators were slow to accept these findings, but subsequent trials and a meta-analysis convincingly confirmed the reduction in mortality by using lung-protective ventilator settings in patients with ARDS [3]. Currently, lung protective ventilation is considered standard of care for ARDS [46]. …
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Metadaten
Titel
From protective ventilation to super-protective ventilation for acute respiratory distress syndrome
verfasst von
Marcus J. Schultz
Nicole P. Juffermans
Michael A. Matthay
Publikationsdatum
01.05.2013
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 5/2013
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-012-2805-8

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