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Intensive Care Medicine

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01.10.2014 | What's New in Intensive Care

What’s new in diagnosis and antimicrobial therapy of febrile neutropenic patients with lung infiltrates?

verfasst von: C. Rieger, S. Barlow, G. Maschmeyer

Erschienen in: Intensive Care Medicine | Ausgabe 10/2014

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Excerpt

In recent years, antineoplastic treatment regimens in hematological patients have intensified. This has led to a significant increase in intensive care unit (ICU) admissions due to severe infectious complications. Among these patients, pulmonary infiltrates are among the most common findings associated with febrile episodes. The increasing availability of high-resolution and multislice computed tomography (CT) has rendered the conventional chest radiograph more or less obsolete for diagnosing lung infiltrates in febrile neutropenic patients. Microbiological, serological, and histopathological diagnostics complement clinical and imaging findings on which therapeutic management is based. …

Heussel CP, Kauczor HU, Heussel G et al (1997) Early detection of pneumonia in febrile neutropenic patients: use of thin section CT. Am J Roentgenol 169:1347–1353CrossRef

Heussel CP, Kauczor HU, Heussel GE et al (1999) Pneumonia in febrile neutropenic patients and in bone marrow and blood stem-cell transplant recipients: use of high resolution computed tomography. J Clin Oncol 17:796–805PubMed

Greene RE, Schlamm HT, Oestmann JW et al (2007) Imaging findings in acute invasive pulmonary aspergillosis: clinical significance of the halo sign. Clin Infect Dis 44:373–379PubMedCrossRef

De Pauw B, Walsh TJ, Donnelly JP et al (2008) Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) consensus group. Clin Infect Dis 46:1813–1821PubMedCrossRefPubMedCentral

Stanzani M, Battista G, Sassi C et al (2012) Computed tomographic pulmonary angiography for diagnosis of invasive mold diseases in patients with hematological malignancies. Clin Infect Dis 54:610–616PubMedCrossRef

Patel NR, Lee PS, Kim JH et al (2005) The influence of diagnostic bronchoscopy on clinical outcomes comparing adult autologous and allogeneic bone marrow transplant patients. Chest 127:1388–1396PubMedCrossRef

Johnson GL, Sarker SJ, Hill K et al (2013) Significant decline in galactomannan signal during storage of clinical serum samples. Int J Mol Sci 14:12970–12977PubMedCrossRefPubMedCentral

Buchheidt D, Baust C, Skladny H et al (2001) Detection of Aspergillus species in blood and bronchoalveolar lavage samples from immunocompromised patients by means of 2-step polymerase chain reaction: clinical results. Clin Infect Dis 33:428–457PubMedCrossRef

Ascioglou S, Rex JH, de Pauw B et al (2002) Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 34:7–14CrossRef

10.

Shah AA, Hazen KC (2013) Diagnostic accuracy of histopathologic and cytopathologic examination of Aspergillus species. Am J Clin Pathol 139:55–61PubMedCrossRef

11.

Limper AH, Knox KS, Sarosi GA et al (2011) An official American Thoracic Society statement: treatment of fungal infections in adult pulmonary and critical care patients. Am J Respir Crit Care Med 183:96–128PubMedCrossRef

12.

Mousset S, Buchheidt D, Heinz W et al (2014) Treatment of invasive fungal infections in cancer patients—updated recommendations of the infectious diseases working party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Ann Hematol 93:13–32PubMedCrossRefPubMedCentral

13.

Maschmeyer G, Carratalà J, Buchheidt D et al (2014) Diagnosis and antimicrobial therapy of lung infiltrates in febrile neutropenic patients (allogeneic SCT excluded)—updated guidelines of the infectious diseases working party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO). Ann Oncol in press

14.

Vardakas KZ, Tansarli GS, Bliziotis IA et al (2013) β-Lactam plus aminoglycoside or fluoroquinolone combination versus β-lactam monotherapy for Pseudomonas aeruginosa infections: a meta-analysis. Int J Antimicrob Agents 41:301–310PubMedCrossRef

15.

Azoulay E, Mokart D, Pène F et al (2013) Outcomes of critically ill patients with hematologic malignancies: prospective multicenter data from France and Belgium–a groupe de recherche respiratoire en réanimation onco-hématologique study. J Clin Oncol 31:2810–2818PubMedCrossRef

Titel: What’s new in diagnosis and antimicrobial therapy of febrile neutropenic patients with lung infiltrates?
verfasst von: C. Rieger
S. Barlow
G. Maschmeyer
Publikationsdatum: 01.10.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 10/2014
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-014-3368-7

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