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Erschienen in: Intensive Care Medicine 10/2014

01.10.2014 | Editorial

Impact of de-escalation on ICU patients’ prognosis

verfasst von: Jan J. De Waele, Matteo Bassetti, Ignacio Martin-Loeches

Erschienen in: Intensive Care Medicine | Ausgabe 10/2014

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Excerpt

De-escalation has been advocated to reduce antibiotic pressure and has become an integrated part of antimicrobial stewardship programs and antimicrobial therapy guidelines [1]. The goal of de-escalation is to reduce the use of broad-spectrum antibiotics when bacterial susceptibility allows this. As such, it has become a necessity as proposed empirical antibiotic therapy for severe infection most often consists of multiple and broad-spectrum antibiotics. The application of de-escalation in real life is rather disappointing and ranges from 13 to 43 % [26] depending on the definition used and context studied. …
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Metadaten
Titel
Impact of de-escalation on ICU patients’ prognosis
verfasst von
Jan J. De Waele
Matteo Bassetti
Ignacio Martin-Loeches
Publikationsdatum
01.10.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Intensive Care Medicine / Ausgabe 10/2014
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-014-3488-0

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