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Intensive Care Medicine

Erschienen in:

01.11.2014 | Review

Mechanisms of the effects of prone positioning in acute respiratory distress syndrome

verfasst von: C. Guerin, L. Baboi, J. C. Richard

Erschienen in: Intensive Care Medicine | Ausgabe 11/2014

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Abstract

Introduction

Prone positioning has been used for many years in patients with acute respiratory distress syndrome (ARDS). The initial reason for prone positioning in ARDS patients was improvement in oxygenation. It was later shown that mechanical ventilation in the prone position can be less injurious to the lung and hence the primary reason to use prone positioning is prevention of ventilator-induced lung injury (VILI).

Material and methods

A large body of physiologic benefits of prone positioning in ARDS patients accumulated but these failed to translate into clinical benefits. More recently, meta-analyses and randomized controlled trial in a specific subgroup of ARDS patients demonstrated that prone positioning can improve survival. This review covers the effects of prone positioning on oxygenation, respiratory mechanics, and VILI.

Conclusions

We conclude with the effects of prone positioning on patient outcome, in particular on survival.

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Titel: Mechanisms of the effects of prone positioning in acute respiratory distress syndrome
verfasst von: C. Guerin
L. Baboi
J. C. Richard
Publikationsdatum: 01.11.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 11/2014
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-014-3500-8

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