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Erschienen in: Intensive Care Medicine 2/2015

01.02.2015 | Original

The association between ICU level of care and mortality in the Netherlands

verfasst von: Georg Heinrich Kluge, Sylvia Brinkman, Giel van Berkel, Johannes van der Hoeven, Crétien Jacobs, Yvonne E. M. Snel, John P. W. Vogelaar, Nicolette F. de Keizer, Emiel S. Boon

Erschienen in: Intensive Care Medicine | Ausgabe 2/2015

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Abstract

Purpose

The relationship between the number of patients admitted to an intensive care unit (ICU) volume and mortality is currently the subject of debate. After implementation of a national guideline in 2006, all Dutch ICUs have been classified into three levels based on ICU size, patient volume, ventilation days, and staffing. The goal of this study is to investigate the association between ICU level and mortality of ICU patients in the Netherlands.

Methods

We analyzed data from 132,159 patients admitted to 87 ICUs between January 1, 2009 and October 1, 2011. Logistic GEE analyses were performed to assess the influence of ICU level on in-hospital mortality and 90-day mortality in the total ICU population and in different ICU subgroups while adjusting for severity of illness by APACHE IV.

Results

No significant differences were found in the adjusted in-hospital mortality of the total ICU population and in different subgroups admitted to level 1, 2 and 3 ICUs. In-hospital mortality in level 2 and 3 ICUs as opposed to level 1 ICUs was 1.06 (0.93–1.22) and 1.10 (0.94–1.29), respectively, and 90-day mortality was 0.92 (0.80–1.06) and 1.01 (0.88–1.17).

Conclusion

We demonstrated that ICU level was not associated with significant differences in the case-mix adjusted in-hospital and long-term mortality of ICU patients. This finding is in contrast with some earlier studies suggesting a volume–outcome relationship. Our results may be explained by the successful implementation of nationwide mandatory quality requirements and adequate staffing in all three levels of ICUs over the last years.
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Literatur
1.
Zurück zum Zitat Kanhere MH, Kanhere HA, Cameron A, Maddern GJ (2012) Does patient volume affect clinical outcomes in adult intensive care units? Intensive Care Med 38:741–751PubMedCrossRef Kanhere MH, Kanhere HA, Cameron A, Maddern GJ (2012) Does patient volume affect clinical outcomes in adult intensive care units? Intensive Care Med 38:741–751PubMedCrossRef
2.
Zurück zum Zitat Kahn JM, Linde-Zwirble WT, Wunsch H et al (2008) Potential value of regionalized intensive care for mechanically ventilated medical patients. Am J Respir Crit Care Med 177:285–291PubMedCentralPubMedCrossRef Kahn JM, Linde-Zwirble WT, Wunsch H et al (2008) Potential value of regionalized intensive care for mechanically ventilated medical patients. Am J Respir Crit Care Med 177:285–291PubMedCentralPubMedCrossRef
4.
Zurück zum Zitat Kahn JM, Goss CH, Heagerty PJ, Kramer AA, O’Brien CR, Rubenfeld GD (2006) Hospital volume and the outcomes of mechanical ventilation. New Engl J Med 355:41–50PubMedCrossRef Kahn JM, Goss CH, Heagerty PJ, Kramer AA, O’Brien CR, Rubenfeld GD (2006) Hospital volume and the outcomes of mechanical ventilation. New Engl J Med 355:41–50PubMedCrossRef
5.
Zurück zum Zitat Shahin J, Harrison DA, Rowan KM (2014) Is the volume of mechanically ventilated admissions to UK critical care units associated with improved outcomes? Intensive Care Med 40:353–360PubMedCrossRef Shahin J, Harrison DA, Rowan KM (2014) Is the volume of mechanically ventilated admissions to UK critical care units associated with improved outcomes? Intensive Care Med 40:353–360PubMedCrossRef
6.
Zurück zum Zitat Walkey AJ, Wiener RS (2014) Hospital case volume and outcomes among patients hospitalized with severe sepsis. Am J Respir Crit Care Med 189:548–555PubMedCrossRef Walkey AJ, Wiener RS (2014) Hospital case volume and outcomes among patients hospitalized with severe sepsis. Am J Respir Crit Care Med 189:548–555PubMedCrossRef
7.
Zurück zum Zitat Peelen L, de Keizer NF, Peek N, Scheffer GJ, van der Voort PHJ, de Jonge E (2007) The influence of volume and intensive care unit organisation on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study. Crit Care 11:R40PubMedCentralPubMedCrossRef Peelen L, de Keizer NF, Peek N, Scheffer GJ, van der Voort PHJ, de Jonge E (2007) The influence of volume and intensive care unit organisation on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study. Crit Care 11:R40PubMedCentralPubMedCrossRef
8.
Zurück zum Zitat Cooke CR, Kennedy EH, Wiitala W, Almenoff P, Sales AE, Iwashyna TJ (2012) Despite variation in volume, Veterans Affairs hospitals show consistent outcomes among patients with non-postoperative mechanical ventilation. Crit Care Med 40:2569–2575PubMedCrossRef Cooke CR, Kennedy EH, Wiitala W, Almenoff P, Sales AE, Iwashyna TJ (2012) Despite variation in volume, Veterans Affairs hospitals show consistent outcomes among patients with non-postoperative mechanical ventilation. Crit Care Med 40:2569–2575PubMedCrossRef
9.
Zurück zum Zitat Fernandez R, Altaba S, Cabre L et al (2013) Relationship between volume and survival in closed intensive care units is weak and apparent only in mechanically ventilated patients. Anesthesiology 119:871–879PubMedCrossRef Fernandez R, Altaba S, Cabre L et al (2013) Relationship between volume and survival in closed intensive care units is weak and apparent only in mechanically ventilated patients. Anesthesiology 119:871–879PubMedCrossRef
10.
Zurück zum Zitat Durairaj L, Torner JC, Chriskhilles EA et al (2005) Hospital volume-outcome relationships among medical admissions to ICUs. Chest 128:1682–1689PubMedCrossRef Durairaj L, Torner JC, Chriskhilles EA et al (2005) Hospital volume-outcome relationships among medical admissions to ICUs. Chest 128:1682–1689PubMedCrossRef
11.
Zurück zum Zitat Reinikainen M, Karlsson S, Varpula T et al (2010) Are small hospitals with small intensive care units able to treat patients with severe sepsis? Intensive Care Med 36:673–679PubMedCrossRef Reinikainen M, Karlsson S, Varpula T et al (2010) Are small hospitals with small intensive care units able to treat patients with severe sepsis? Intensive Care Med 36:673–679PubMedCrossRef
12.
Zurück zum Zitat Moran JL, Solomon PJ, ANZICS Centre for Outcome and Resource Evaluation of the Australian and New Zealand Intensive Care Society (2012) Mortality and intensive care volume in ventilated patients from 1995 to 2009 in the Australian and New Zealand binational adult patient intensive care database. Crit Care Med 40:800–812PubMedCrossRef Moran JL, Solomon PJ, ANZICS Centre for Outcome and Resource Evaluation of the Australian and New Zealand Intensive Care Society (2012) Mortality and intensive care volume in ventilated patients from 1995 to 2009 in the Australian and New Zealand binational adult patient intensive care database. Crit Care Med 40:800–812PubMedCrossRef
18.
Zurück zum Zitat Zimmerman JE, Kramer AA, McNair DS, Malila FM (2006) Acute Physiology and Chronic Health Evaluation (APACHE) IV: hospital mortality assessment for today’s critically ill patients. Crit Care Med 34:1297–1310PubMedCrossRef Zimmerman JE, Kramer AA, McNair DS, Malila FM (2006) Acute Physiology and Chronic Health Evaluation (APACHE) IV: hospital mortality assessment for today’s critically ill patients. Crit Care Med 34:1297–1310PubMedCrossRef
19.
Zurück zum Zitat Arts D, de Keizer N, Scheffer GJ, De Jonge E (2002) Quality of data collected for severity of illness scores in the Dutch National Intensive Care Evaluation (NICE) registry. Intensive Care Med 28:656–659PubMedCrossRef Arts D, de Keizer N, Scheffer GJ, De Jonge E (2002) Quality of data collected for severity of illness scores in the Dutch National Intensive Care Evaluation (NICE) registry. Intensive Care Med 28:656–659PubMedCrossRef
21.
Zurück zum Zitat Roos LL, Wajda A (1991) Record linkage strategies. Part I: estimating information and evaluating approaches. Methods Inf Med 30:117–123PubMed Roos LL, Wajda A (1991) Record linkage strategies. Part I: estimating information and evaluating approaches. Methods Inf Med 30:117–123PubMed
23.
Zurück zum Zitat Zeger SL, Liang KY (1986) Longitudinal data analysis for discrete and continuous outcomes. Biometrics 42:121–130PubMedCrossRef Zeger SL, Liang KY (1986) Longitudinal data analysis for discrete and continuous outcomes. Biometrics 42:121–130PubMedCrossRef
24.
Zurück zum Zitat R Development Core Team (2011) R: A Language and Environment for Statistical Computing. The R Foundation for Statistical Computing, Vienna. Available online at http://www.R-project.org/ Accessed 18 Oct 2014 R Development Core Team (2011) R: A Language and Environment for Statistical Computing. The R Foundation for Statistical Computing, Vienna. Available online at http://​www.​R-project.​org/​ Accessed 18 Oct 2014
25.
Zurück zum Zitat Brinkman S, Abu-Hanna A, van der Veen A, de Jonge E, de Keizer NF (2012) A comparison of the performance of a model based on administrative data and a model based on clinical data: effect of severity of illness on standardized mortality ratios of intensive care units. Crit Care Med 40:373–378PubMedCrossRef Brinkman S, Abu-Hanna A, van der Veen A, de Jonge E, de Keizer NF (2012) A comparison of the performance of a model based on administrative data and a model based on clinical data: effect of severity of illness on standardized mortality ratios of intensive care units. Crit Care Med 40:373–378PubMedCrossRef
26.
Zurück zum Zitat Milstein A, Galvin RS, Delbanco SF, Salber P, Buck CR Jr (2000) Improving the safety of health care: the Leapfrog initiative. Eff Clin Pract 3:313–316 (Erratum, Eff Clin Pract 2001;4:94)PubMed Milstein A, Galvin RS, Delbanco SF, Salber P, Buck CR Jr (2000) Improving the safety of health care: the Leapfrog initiative. Eff Clin Pract 3:313–316 (Erratum, Eff Clin Pract 2001;4:94)PubMed
28.
Zurück zum Zitat Bellomo R, Stow PJ, Hart GK (2007) Why is there such a difference in outcome between Australian intensive care units and others? Curr Opin Anaesthesiol 20:100–105PubMedCrossRef Bellomo R, Stow PJ, Hart GK (2007) Why is there such a difference in outcome between Australian intensive care units and others? Curr Opin Anaesthesiol 20:100–105PubMedCrossRef
29.
Zurück zum Zitat Wunsch H, Angus DC, Harrison DA et al (2008) Variation in critical care services across North America and Western Europe. Crit Care Med 36:2787–2793PubMedCrossRef Wunsch H, Angus DC, Harrison DA et al (2008) Variation in critical care services across North America and Western Europe. Crit Care Med 36:2787–2793PubMedCrossRef
Metadaten
Titel
The association between ICU level of care and mortality in the Netherlands
verfasst von
Georg Heinrich Kluge
Sylvia Brinkman
Giel van Berkel
Johannes van der Hoeven
Crétien Jacobs
Yvonne E. M. Snel
John P. W. Vogelaar
Nicolette F. de Keizer
Emiel S. Boon
Publikationsdatum
01.02.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Intensive Care Medicine / Ausgabe 2/2015
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-014-3620-1

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