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Intensive Care Medicine

Erschienen in:

01.10.2015 | Original

Effect of a quality improvement program on weaning from mechanical ventilation: a cluster randomized trial

verfasst von: Bo Zhu, Zhiqiang Li, Li Jiang, Bin Du, Qi Jiang, Meiping Wang, Ran Lou, Xiuming Xi

Erschienen in: Intensive Care Medicine | Ausgabe 10/2015

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Abstract

Purpose

To evaluate the efficacy of a quality improvement (QI) program for protocol-directed weaning from mechanical ventilation.

Methods

This was a prospective, cluster randomized controlled trial. The study consisted of a baseline phase and a QI phase. Fourteen intensive care units (ICUs) in Beijing, China, were randomized into the QI group and non-QI group. The QI group received a QI program to improve the compliance with protocol-directed weaning during the QI phase.

Results

A total of 444 patients were enrolled in the non-QI group (193 for the baseline, 251 for the QI phase) and 440 in the QI group (199 for the baseline, 241 for the QI phase). During the QI phase in the QI group, compared with the non-QI group, total duration of mechanical ventilation decreased from 7.0 to 3.0 days (p = 0.003), the time before the first weaning attempt decreased from 3.63 to 1.96 days (p = 0.003), length of ICU stay decreased from 10.0 to 6.0 days (p = 0.004), length of hospital stay decreased from 23.0 to 19.0 days (p < 0.001). These differences were also significant in the QI group when the QI phase was compared with the baseline phase. In addition, there was a significant reduction in the percentage of mechanical ventilation exceeding 21 days (p = 0.001) when the baseline phase was compared with the QI phase in the QI group.

Conclusions

The QI program involving protocol-directed weaning is associated with beneficial clinical outcomes in mechanically ventilated patients.

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Titel: Effect of a quality improvement program on weaning from mechanical ventilation: a cluster randomized trial
verfasst von: Bo Zhu
Zhiqiang Li
Li Jiang
Bin Du
Qi Jiang
Meiping Wang
Ran Lou
Xiuming Xi
Publikationsdatum: 01.10.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 10/2015
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-015-3958-z

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Effect of a quality improvement program on weaning from mechanical ventilation: a cluster randomized trial

Abstract

Purpose

Methods

Results

Conclusions

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Springer Medizin

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Conclusions

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