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03.05.2017 | Review

The ICM research agenda on extracorporeal life support

verfasst von: Alain Combes, Dan Brodie, Yih-Sharng Chen, Eddy Fan, José P. S. Henriques, Carol Hodgson, Philipp M. Lepper, Pascal Leprince, Kunihiko Maekawa, Thomas Muller, Sebastian Nuding, Dagmar M. Ouweneel, Antoine Roch, Matthieu Schmidt, Hiroo Takayama, Alain Vuylsteke, Karl Werdan, Laurent Papazian

Erschienen in: Intensive Care Medicine | Ausgabe 9/2017

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Abstract

Purpose

This study aimed to concisely describe the current standards of care, major recent advances, common beliefs that have been contradicted by recent trials, areas of uncertainty, and clinical studies that need to be performed over the next decade and their expected outcomes with regard to extracorporeal membrane oxygenation (ECMO).

Methods

Narrative review based on a systematic analysis of the medical literature, national and international guidelines, and expert opinion.

Results

The use of venovenous ECMO (VV-ECMO) is increasing in the most severe forms of acute lung injury. In patients with cardiogenic shock, short-term veno-arterial ECMO (VA-ECMO) provides both pulmonary and circulatory support. Technological improvements and recently published studies suggest that ECMO is able to improve patients’ outcomes. There are, however, many uncertainties regarding the real benefits of this technique both in hemodynamic and respiratory failure, the territorial organization to deliver ECMO, the indications and the use of concomitant treatments.

Conclusions

Although there have been considerable advances regarding the use of ECMO in critically ill patients, the risk/benefit ratio remains underinvestigated. ECMO indications, organization of ECMO delivery, and use of adjuvant therapeutics need also to be explored. Ongoing and future studies may be able to resolve these issues.

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Titel: The ICM research agenda on extracorporeal life support
verfasst von: Alain Combes
Dan Brodie
Yih-Sharng Chen
Eddy Fan
José P. S. Henriques
Carol Hodgson
Philipp M. Lepper
Pascal Leprince
Kunihiko Maekawa
Thomas Muller
Sebastian Nuding
Dagmar M. Ouweneel
Antoine Roch
Matthieu Schmidt
Hiroo Takayama
Alain Vuylsteke
Karl Werdan
Laurent Papazian
Publikationsdatum: 03.05.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 9/2017
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4803-3

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

The ICM research agenda on extracorporeal life support

Abstract

Purpose

Methods

Results

Conclusions

Neu im Fachgebiet AINS

Hinter dieser Appendizitis steckte ein Erreger

Ärztliche Empathie hilft gegen Rückenschmerzen

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

Stereotaktische Radiatio schlägt konventionelle Bestrahlung

Update AINS

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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Intensive care medicine research agenda on cardiac arrest

The intensive care medicine clinical research agenda in paediatrics

The intensive care medicine research agenda in nutrition and metabolism

Neu im Fachgebiet AINS

Hinter dieser Appendizitis steckte ein Erreger

Ärztliche Empathie hilft gegen Rückenschmerzen

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

Stereotaktische Radiatio schlägt konventionelle Bestrahlung

Update AINS