Erschienen in:
22.11.2017 | Understanding the Disease
Understanding the role of host immune responses in invasive candidiasis
verfasst von:
Jigar V. Desai, Frank L. van de Veerdonk, Michail S. Lionakis
Erschienen in:
Intensive Care Medicine
|
Ausgabe 8/2018
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Excerpt
Invasive candidiasis is the most common nosocomial bloodstream mycosis in the ICU affecting > 250,000 individuals annually worldwide [
1]. It is most often caused by
Candida albicans, a commensal yeast of mucosal surfaces, although infections by non-
albicans species, including
C. glabrata,
C. tropicalis and
C. parapsilosis are increasing [
1]. The recent global emergence of
C. auris raises public health concerns because of the species’ multidrug-resistance and resilience to antiseptics, its misidentification by routine microbiological techniques, and its persistence on human skin and hospital environment that causes hospital-associated horizontal transmission and outbreaks [
2]. …