nach oben

Knee Surgery, Sports Traumatology, Arthroscopy

Erschienen in:

01.05.2007 | Knee

Meniscus allograft transplantation: a current concepts review

verfasst von: James H. Lubowitz, Peter C. M. Verdonk, John B. Reid III, René Verdonk

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 5/2007

Einloggen, um Zugang zu erhalten

Abstract

Meniscus allotransplantation represents the biological solution for the symptomatic, meniscus-deficient patient who has not developed advanced osteoarthritis. A growing body of evidence suggests that pain relief and functional improvement may reliably be achieved at short- and medium-term follow-up, and even, in some cases, at long-term (>10 years) follow-up. Future research must address the issue of optimal timing of the procedure and whether meniscal transplantation results in demonstrable long-term benefits, especially with regard to protection of articular cartilage.

Fairbank TJ (1948) Knee joint changes after meniscectomy. J Bone Joint Surg Br 30B:664–670PubMed

Cole BJ, Carter TR, Rodeo SA (2003) Allograft meniscal transplantation: background, techniques, and results. Instr Course Lect 52:383–396PubMed

Locht RC, Gross AE, Langer F (1984) Late osteochondral resurfacing for tibial plateau fractures. J Bone Joint Surg Am 66:328–335PubMed

Milachowski KA, Weismeier K, Wirth CJ (1989) Homologous meniscal transplantation: Experimental and clinical results. Int Orthop 13:1–11PubMed

Levy IM, Torzilli PA, Warren RF (1982) The effect of medial meniscectomy on anterior-posterior motion of the knee. J Bone Joint Surg Am 64:883–888PubMed

Helfet AJ (1959) Mechanism of derangements of the medial semilunar cartilage and their management. J Bone Joint Surg Br 41:319–336PubMed

Levy IM, Torzilli PA, Gould JD, Warren RF (1989) The effect of lateral meniscectomy on motion of the knee. J Bone Joint Surg Am 71:401–406PubMed

MacConaill MA (1931) The function of intra-articular fibrocartilages, with special reference to the knee and inferior radiolunar joints. J Anat 66:210–227

Simon WH, Friedenberg S, Richardson S (1973) Joint congruence: a correlation of joint congruence and thickness of articular cartilage in dogs. J Bone Joint Surg Am 55:1614–1620PubMed

10.

Walker PS, Erkman MJ (1975) The role of the menisci in force transmission across the knee. Clin Orthop 109:184–192PubMed

11.

Simonian PT, Sussmann PS, van Trommel M, Wickiewicz TL, Warren RF (1997) Popliteomeniscal fasciculi and lateral meniscal stability. Am J Sports Med 25:849–853PubMed

12.

Staubli HU, Birrer S (1990) The popliteus tendon and its fascicles at the popliteal hiatus: gross anatomy and functional arthroscopic evaluation with and without anterior cruciate ligament deficiency. Arthroscopy 6:209–220PubMedCrossRef

13.

Thompson WO, Thaete FL, Fu FH, Dye SF (1991) Tibial meniscal dynamics using three-dimensional reconstruction of magnetic resonance images. Am J Sports Med 19:210–216PubMed

14.

Arnoczky SP, McDevitt CA (2000) The meniscus: structure, function, repair and replacement. In: Buckwalter JA, Einhorn TA, Simon SR (eds) Orthopaedic basic science: biology and biomechanics of the musculoskeletal system. 2nd ed American Academy of Orthopaedic Surgeons, Rosemont, pp 531–545

15.

Arnoczky SP, Warren RF (1982) Microvasculature of the human meniscus. Am J Sports Med 10:90–95PubMed

16.

Fithian DC, Kelly MA, Mow VC (1990) Material properties and structure–function relationships in the menisci. Clin Orthop 252:19–31PubMed

17.

Favenesi JA, Shaffer JC, Mow VC (1983) Biphasic mechanical properties of knee meniscus. Trans Orthop Res Soc 7:264–265

18.

Rijk PC (2004a) Meniscal allograft transplantation—part I: background, results, graft selection and preservation, and surgical considerations. Arthroscopy 20:728–743

19.

Rodeo SA (2001) Meniscal allografts—where do we stand? Am J Sports Med 29:246–261PubMed

20.

Arnoczky SP, DiCarlo EF, O’Brien SJ, Warren RF (1992) Cellular repopulation of deep-frozen meniscal autografts: an experimental study in the dog. Arthroscopy 8:428–436PubMedCrossRef

21.

Day B, Mackenzie WG, Shim SS, Leung G (1985) The vascular and nerve supply of the human meniscus. Arthroscopy 1:58–62PubMedCrossRef

22.

Zimny ML, Albright DL, Dabeziew E (1988) Mechanoreceptors in the human medial meniscus. Acta Anat 133:35–40PubMedCrossRef

23.

Jackson DW, Whelan J, Simon TM (1993) Cell survival after transplantation of fresh meniscal allografts: DNA probe analysis in a goat model. Am J Sports Med 21:540–550PubMed

24.

Verdonk R (1997) Alternative treatment for meniscal injuries. J Bone Joint Surg 79B:866–873

25.

Verdonk R, Van Daele P, Claus B et al (1994) Viable meniscus transplantation (in German). Orthopade 23(2):153–159PubMed

26.

Arnoczky SP, Milachowski KA (1990) Meniscal allografts: where do we stand? In: Ewing JW (ed) Articular cartilage and knee joint function: basic science and arthroscopy. Raven, New York, pp 129–136

27.

Siegel MG, Roberts CS (1993a) Meniscal allografts. Clin Sports Med 12:59–80

28.

Brown KL, Cruess RL (1982) Bone and cartilage transplantation in orthopaedic surgery. A review. J Bone Joint Surg Am 64:270–279PubMed

29.

Khoury MA, Goldberg VM, Stevenson S (1994) Demonstration of HLA and ABH antigens in fresh and frozen human menisci by immunohistochemistry. J Orthop Res 12:751–757PubMed

30.

Milachowski KA, Weismeier K, Erhardt W, Remberger K (1987) Transplantation of the meniscus: an experimental study in sheep. Sportverletzung Sportschaden 1:20–24PubMedCrossRef

31.

Garrett JC, Stevensen RN (1991) Meniscal transplantation in the human knee. A preliminary report. Arthroscopy 7:57–62PubMedCrossRef

32.

Jackson DW, Windler GE, Simon TM (1990a) Intraarticular reaction associated with the use of freeze-dried, ethylene oxide-sterilized bone-patella tendon-bone allografts in the reconstruction of the anterior cruciate ligament. Am J Sports Med 18:1–11

33.

Rijk PC (2004b) Meniscal allograft transplantation—part II: alternative treatments, effects on articular cartilage, and future directions. Arthroscopy 20:851–859

34.

Rodeo SA, Seneviratne A, Suzuki K, Felker K, Wickiewicz TL, Warren RF (2000) Histological analysis of human meniscal allografts: a preliminary report. J Bone Joint Surg Am 82:1071–1082PubMed

35.

Jackson DW, McDevitt CA, Simon TM, Arnoczky SP, Atwell EA, Silvino NJ (1992) Meniscal transplantation using fresh and cryopreserved allografts: an experimental study in goats. Am J Sports Med 20:644–656PubMed

36.

Noyes FR, Barber-Westin SD (1995) Irradiated meniscus allografts in the human knee: a two to five year follow-up study. Orthop Trans 19:417

37.

Alhalki MM, Hull ML, Howell SM (2000a) Contact mechanics of the medial tibial plateau after implantation of a medial meniscal allograft. A human cadaveric study. Am J Sports Med 28:370–376

38.

Noyes FR, Barber-Westin SD, Rankin M (2005) Meniscal transplantation in symptomatic patients less than fifty-years old. J Bone Joint Surg Am 87:149–165PubMed

39.

Bos GD, Goldberg VM, Zika JM, Heiple KG, Powell AE (1983) Immune responses of rats to frozen bone allografts. J Bone Joint Surg Am 65:239–246PubMed

40.

Stevenson S (1987) The immune response to osteochondral allografts in dogs. J Bone Joint Surg Am 69:573–582PubMed

41.

Wada Y (1993) Meniscal transplantation using fresh and cryopreserved allografts. An experimental study in the genetically defined rat. J Jpn Orthop Assoc 67:677–683

42.

Zukor DJ, Cameron JC, Brooks PJ et al (1990) The fate of human meniscal allografts. In: Ewing JW (ed) Articular cartilage and knee joint function. Raven, New York, pp 147–152

43.

Hamlet W, Liu SH, Yang R (1997) Destruction of a cryopreserved meniscal allograft: a case for acute rejection. Arthroscopy 13:517–521PubMedCrossRef

44.

van Arkel ERA, van den Berg-Loonen EM, van Wersch JW, de Boer HH (1997) Human leukocyte antigen sensitization after cryopreserved human meniscal transplantations. Transplantation 64:531–533PubMed

45.

Buck BE, Resnick L, Shah SM, Malinin TI (1990) Human immunodeficiency virus cultured from bone. Implications for transplantation. Clin Orthop 251:249–253PubMed

46.

Nemzek JA, Arnoczky SP, Swenson CL (1994) Retroviral transmission by the transplantation of connective-tissue allografts: an experimental study. J Bone Joint Surg Am 76:1036–1041PubMed

47.

Conway B, Tomford W, Mankin HJ, Hirsch MS, Schooley RT (1991) Radiosensitivity of HIV-I: potential application to sterilization of bone allografts. AIDS 5:608–609PubMed

48.

Yahai L, Zukor D (1994) Irradiated meniscal allotransplants of rabbits: study of the mechanical properties at six months post-operation. Acta Orthop Belg 60:210–215

49.

Jackson DW, Windler GE, Simon TM (1990b) Intra-articular reaction associated with the use of freeze-dried, ethylene oxide-sterilized bone patella tendon-bone allografts in the reconstruction of the anterior cruciate ligament. Am J Sports Med 18:1–11

50.

Barber FA (1994) Accelerated rehabilitation for meniscus repairs. Arthroscopy 10:206–210PubMedCrossRef

51.

Johnson DL, Bealle D (1999) Meniscal allograft transplantation. Clin Sports Med 18:93–108PubMed

52.

Dye SF, Chew MH (1993) The use of scintigraphy to detect increased osseous metabolic activity about the knee. J Bone Joint Surg Am 75:1388–1406

53.

Potter HG, Linklater JM, Allen AA, Hannafin JA, Haas SB (1998a) Magnetic resonance imaging of articular cartilage in the knee. An evaluation with use of fast-spin-echo imaging. J Bone Joint Surg Am 81:1349–1350

54.

Garrett JC (1993) Meniscal transplantation: a review of 43 cases with 2- to 7- year follow-up. Sports Med Arthrosc Rev 1:164–167

55.

Aagaard H, Jorgenssen U, Bojsen-Moller F (1999) Reduced degenerative articular cartilage changes after meniscal allograft transplantation in sheep. Knee Surg Sports Traumatol Arthrosc 7:184–191PubMed

56.

Siegel MG, Roberts CS (1993b) Meniscal allografts. Clin Sports Med 12:59–80

57.

Cole BJ, Cohen B (2000) Chondral injuries of the knee. A contemporary view of cartilage restoration. Orthop Spec Ed 6:71–76

58.

Goble EM (2004) Arthroscopic meniscus transplantation: plug and slot technique. In: Miller M, Cole BJ (eds) Textbook of arthroscopy. WB Saunders, Philadelphia, pp 536–546

59.

Rosenberg TD, Paulos LE, Parker RD et al (1988) The forty-five-degree posteroanterior flexion weight-bearing radiograph of the knee. J Bone Joint Surg Am 70:1479–1483PubMed

60.

Potter HG, Linklater JM, Allen AA et al (1998b) Magnetic resonance imaging of articular cartilage in the knee. An evaluation with use of fast-spin-echo imaging. J Bone Joint Surg Am 80:1276–1284

61.

Berlet GC, Fowler PJ (1998) The anterior horn of the medial meniscus. An anatomic study of its insertion. Am J Sports Med 26:540–543PubMed

62.

Verdonk R, Kohn D (1999) Harvest and conservation of meniscal allografts. Scand J Med Sci Sports 9:158–159PubMedCrossRef

63.

Wilcox TR, Goble EM, Doucette SA (1996) Goble technique of meniscus transplantation. Am J Knee Surg 9:37–42PubMed

64.

Kohn D (1994) Meniscus transplantation. In: Fu FH (ed) Advances in operative orthopaedics. Mosby-Year Book, Chicago, 2:49–76

65.

Johnson DL, Swenson TM, Livesay GA, Aizawa H, Fu FH, Harner CD (1995) Insertion-site anatomy of the human menisci: gross, arthroscopic, and topographical anatomy as a basis for meniscal transplantation. Arthroscopy 11:386–394PubMedCrossRef

66.

Garrett JC (1992) Meniscal transplantation. In: Aichroth PC, Canon WD, Patel DV (eds) Knee surgery: current practice. Raven, New York, pp 95–103

67.

Johnson DL, Swenson TM, Harner CD (1994) Meniscal reconstruction using allograft tissue: an arthroscopic technique. Oper Tech Sports Med 2:223–231

68.

Shaffer B, Kennedy S, Klimkiewicz J, Yao L (2000) Preoperative sizing of meniscal allografts in meniscus transplantation. Am J Sports Med 28:524–533PubMed

69.

Haut TL, Hull ML, Howell SM (2000) Use of roentgenography and magnetic resonance imaging to predict meniscal geometry determined with a three-dimensional coordinate digitizing system. J Orthop Res 18:228–237PubMed

70.

Pollard ME, Kang Q, Berg EE (1995) Radiographic sizing for meniscal transplantation. Arthroscopy 11:684–687PubMedCrossRef

71.

Chen MI, Branch TP, Hutton WC (1996) Is it important to secure the horns during lateral meniscal transplantation? A cadaveric study. Arthroscopy 12:174–181PubMedCrossRef

72.

Paletta GA Jr, Manning T, Snell E, Parker R, Bergfeld J (1997) The effect of allograft meniscal replacement on intraarticular contact area and pressures in the human knee: a biomechanical study. Am J Sports Med 25:692–698PubMed

73.

Alhalki MM, Howell SM, Hull ML (1999) How three methods for fixing a medial meniscal autograft affect tibial contact mechanics. Am J Sports Med 27:320–328PubMed

74.

Verdonk PCM, Demurie A, Almqvist KF, Veys EM, Verbruggen G, Verdonk R (2006) Transplantation of viable meniscal allograft. J Bone Joint Surg Am 88(1 Suppl 1):109–118PubMed

75.

Kohn D, Moreno B (1995) Meniscus insertion anatomy as a basis for meniscus replacement: a morphological cadaveric study. Arthroscopy 11:96–103PubMedCrossRef

76.

Kuhn JE, Wojtys EM (1996) Allograft meniscal transplantation. Clin Sports Med 15:537–556PubMed

77.

Goble EM, Kohn D, Verdonk R, Kane SM (1999) Meniscal substitutes-human experience. Scand J Med Sci Sports 9:146–157PubMedCrossRef

78.

Cameron JC, Saha S (1997) Meniscal allograft transplantation for unicompartmental arthritis of the knee. Clin Orthop 337:164–171PubMed

79.

Rath E, Richmond JC, Yassir W, Albright JD, Gundogan F (2001) Meniscal allograft transplantation. Two-to-eight-year results. Am J Sports Med 29:410–414PubMed

80.

Shelton WR, Dukes AD (1994) Meniscus replacement with bone anchors: a surgical technique. Arthroscopy 10:324–327PubMedCrossRef

81.

Mikic ZD, Brankov MZ, Tubic MV, Lazetic AB (1993) Allograft meniscus transplantation in the dog. Acta Orthop Scand 64:329–332PubMedCrossRef

82.

Rijk PC, Van Noorden CJF (2002) Structural analysis of meniscal allografts after immediate and delayed transplantation in rabbits. Arthroscopy 18:995–1001PubMedCrossRef

83.

Stollsteimer GT, Shelton WR, Dukes A, Bomboy AL (2000) Meniscal allograft transplantation: a 1-to-5 year follow-up of 22 patients. Arthroscopy 16:343–347PubMedCrossRef

84.

Fritz JM, Irrgang JJ, Harner CD (1996) Rehabilitation following allograft meniscal transplantation: a review of the literature and case study. J Orthop Sports Phys Ther 24:98–106PubMed

85.

Anderson DR, Gershuni DH, Nakhostine M, Danzig LA (1993) The effects of non-weight-bearing and limited motion on the tensile properties of the meniscus. Arthroscopy 9:440–445PubMedCrossRef

86.

Dowdy PA, Miniaci A, Arnoczky SP, Fowler PJ, Boughner DR (1995) The effect of cast immobilization on meniscal healing: an experimental study in the dog. Am J Sports Med 23:721–728PubMed

87.

Van Arkel ERA, Goei R, de Ploeg I, de Boer HH (2000) Meniscal allografts: evaluation with magnetic resonance imaging and correlation with arthroscopy. Arthroscopy 16:517–521PubMed

88.

Alford W, Cole BJ (2005) The indications and technique for meniscal transplant. Orthop Clin N Am 36:468–484

89.

Verdonk PCM, Demurie A, Almqvist KF, Veys EM, Verbruggen, Verdonk R (2005) Transplantation of viable meniscal allograft: survivorship analysis and clinical outcome of one hundred cases. J Bone Joint Surg Am 87:715–724PubMed

90.

Van Arkel ERA, De Boer HH (2002) Survival analysis of human meniscal transplantation. J Bone Joint Surg Br 84:227–231PubMed

91.

Potter HG, Rodeo SA, Wickiewicz TL et al (1996) MR imaging of meniscal allografts: correlation with clinical and arthroscopic outcomes. Radiology 198:509–514PubMed

92.

Szomor ZL, Martin TE, Bonar F, Murrell GAC (2000) The protective effects of meniscal transplantation on cartilage: an experimental study in sheep. J Bone Joint Surg Am 82:80–88PubMed

93.

Messner K (1999) Meniscal regeneration or meniscal transplantation? Scand J Med Sci Sports 9:162–167PubMedCrossRef

94.

Aagaard H, Jorgensen U, Bojsen-Moller F (2003) Immediate versus delayed meniscal allograft transplantation in sheep. Clin Orthop 406:218–227PubMed

95.

Rijk PC, Tigchelaar-Gutter W, Bernoski FP, Van Noorden CJF (2004) Histologic changes of articular cartilage after meniscus replacement in rabbits. Arthroscopy 20:911–917PubMed

96.

Cummins JF, Mansour JN, Howe Z, Allan DG (1997) Meniscal transplantation and degenerative articular change: an experimental study in the rabbit. Arthroscopy 13:485–491PubMedCrossRef

97.

Elliott DM, Jones R, Setton LA, Sully SP, Vail TP, Guilak F (2002) Joint degeneration following meniscal allograft transplantation in a canine model: mechanical properties and semiquantitative histology of articular cartilage. Knee Surg Sports Traumatol Arthrosc 10:109–118PubMed

98.

Verdonk PCM, Verstraete KL, Almqvist KF, De Cuyper K, Veys EM, Verbruggen G, Verdonk R (2006) Meniscal allograft transplantation: long-term clinical results with radiological and magnetic resonance imaging correlations. Knee Surg Sports Traumatol Arthrosc (Epublication ahead of print)

99.

Messner K, Fahlgren A, Persliden J, Andersen BM (2001) Radiographic joint space narrowing and histologic changes in a rabbit meniscectomy model of early knee osteoarthrosis. Am J Sports Med 2:151–160

100.

Thomas RH, Resnick D, Alazraki NP, Daniel D, Greenfield R (1975) Compartmental evaluation of osteoarthritis of the knee. A comparative study of available diagnostic modalities. Radiology 116:585–594PubMed

101.

Christensen SB (1983) Localization of bone-seeking agents in developing experimentally induced osteoarthritis in the knee joint of the rabbit. Scand J Rheumatology 12:343–349

102.

Rijk PC, Van Eck-Smit BLF, Van Noorden CJF (2003) Scintigraphic assessment of rabbit knee joints after meniscal allograft transplantation. Arthroscopy 19:506–510PubMedCrossRef

103.

Bylski-Austrow DI, Meade T, Malumed J et al (1992) Irradiated meniscal allografts: mechanical and histological studies in the goat. Trans Orthop Res Soc 17:175

104.

Paletta GA Jr, Manning T, Snell E, Parker R, Bergfeld J (1997) The effect of allograft meniscal replacement on intraarticular contact area and pressures in the human knee. A biomechanical study. Am J Sports Med 25(5):692–698PubMed

105.

Alhalki MM, Hull ML, Howell SM (2000) Contact mechanics of the medial tibial plateau after implantation of a medial meniscal allograft: a human cadaveric study. Am J Sports Med 28:370–376PubMed

106.

Chen MI, Branch TP, Hutton WC (1996b) Is it important to secure the horns during lateral meniscal transplantation? A cadaveric study. Arthroscopy 12(2):174–81CrossRef

107.

von Lewinski G, Hurschler C, Allmann C, Wirth CJ (2006) The influence of pre-tensioning of meniscal transplants on the tibiofemoral contact area. Knee Surg Sports Traumatol Arthrosc 14(5):425–436

108.

Moon MS, Woo YK, Kin YI (1988) Meniscal regeneration and its effects on articular cartilage in rabbit knees. Clin Orthop 227:298–304PubMed

109.

Elmer RM, Moskowitz RW, Frankel VH (1977) Meniscal regeneration and postmeniscectomy degenerative joint disease. Clin Orthop 124:304–310PubMed

110.

Ghosh P, Taylor TKF, Pettit GD, Horsburgh BA, Bellanger CR (1983) Effect on postoperative immobilization of the regrowth of the knee joint semilunar cartilage: an experimental study. J Orthop Res 1:153–164PubMed

111.

Stone KR, Rodkey WG, McKinney LA, Steadman JR (1995) Autogenous replacement of the meniscal cartilage: analysis of results and mechanics of failure. Arthroscopy 11:395–400PubMedCrossRef

112.

Bruns J, Kahrs J, Kampen J, Behrens P, Plitz W (1998) Autologous perichondral tissue for meniscal replacement. J Bone Joint Surg Br 80:918–923PubMed

113.

Kohn D, Wirth CJ, Reiss G, Plitz W, Maschek H, Erhardt W, Wulker N (1992) Medial meniscus replacement by a tendon autograft. Experiments in sheep. J Bone Joint Surg Br 74(6):910–917PubMed

114.

Pressel T, v Lewinski G, Kohn D, Wirth CJ (2005) Der Meniskusersatz mit autologer Quadrizepssehne - eine Langzeitanalyse. Z Orthop Ihre Grenzgeb 143(1):42–47PubMed

115.

Yannas IV (1992) Tissue regeneration by use of collagen-glycosaminoglycan copolymers. Clin Mater 9:179–187PubMed

116.

Yannas IV, Burke JF (1980) Design of artificial skin: 1. design principles. J Biomed Mater Res 14:65–81PubMed

117.

Klompmaker J, Veth RP, Jansen HW, Nielsen HK, De Groot JH, Penning AJ (1996) Meniscal replacement using a porous polymer prosthesis: a preliminary study in the dog. Biomaterials 17:1169–1175PubMed

118.

Stone KR, Rodkey WG, Webber R, McKinney L, Steadman JR (1992) Meniscal regeneration with copolymeric collagen scaffolds. In vitro and in vivo studies evaluated clinically, histologically, and biochemically. Am J Sports Med 20:104–111PubMed

119.

Steadman JR, Rodkey WG (2005) Tissue-engineered collagen meniscus implants: 5- to 6-year feasibility study results. Arthroscopy 21(5):515–525PubMedCrossRef

120.

Van Arkel ERA, De Boer HH (1995) Human meniscal transplantation: preliminary results at 2 to 5-year follow-up. J Bone Joint Surg Br 77:589–595PubMed

121.

Carter TR (1999) Meniscal allograft transplantation. Sports Med Arthrosc Rev 7:51–62

122.

Wirth CJ, Peters G, Milachowski KA, Weismeier KG, Kohn D (2002) Long-term results of meniscal allograft transplantation. Am J Sports Med 30:174–181PubMed

123.

Ryu RK, Dunbar VWH, Morse GG (2002) Meniscal allograft replacement: a 1-year to 6-year experience. Arthroscopy 18:989–994PubMedCrossRef

Titel: Meniscus allograft transplantation: a current concepts review
verfasst von: James H. Lubowitz
Peter C. M. Verdonk
John B. Reid III
René Verdonk
Publikationsdatum: 01.05.2007
Verlag: Springer-Verlag
Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 5/2007
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-006-0216-5

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen.
» Jetzt entdecken

Neu im Fachgebiet Orthopädie und Unfallchirurgie

16.04.2024 | Spondylitis ankylosans | Nachrichten

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Meniscus allograft transplantation: a current concepts review

Abstract

Arthropedia

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Vorsicht mit hohen NSAR-Dosen bei ankylosierender Spondylitis!

Brustkrebs in der Vorgeschichte macht Gelenkersatz komplikationsträchtiger

Zwei neue Alternativen zu TNF-Inhibitoren bei axSpA

Diclofenac-Gel versus Ibuprofen bei akuten Rückenschmerzen

Update Orthopädie und Unfallchirurgie

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 5/2007

Functional outcome and general health status in patients after arthroscopic release in adhesive capsulitis

An unusual cause of locking

The value of magnetic resonance imaging in our current management of ACL and meniscal injuries

Inverse knot: a personal sliding knot for arthrosopic surgery

The effect of surface incongruity of grafted plugs in osteochondral grafting: a report of five cases

Removal of a femoral interference screw that migrated posteriorly, using a posterior trans-septal portal: a case report

Arthropedia

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Vorsicht mit hohen NSAR-Dosen bei ankylosierender Spondylitis!

Brustkrebs in der Vorgeschichte macht Gelenkersatz komplikationsträchtiger

Zwei neue Alternativen zu TNF-Inhibitoren bei axSpA

Diclofenac-Gel versus Ibuprofen bei akuten Rückenschmerzen

Update Orthopädie und Unfallchirurgie