nach oben

International Urogynecology Journal

Erschienen in:

01.04.2009 | Original Article

Experimental comparison of abdominal wall repair using different methods of enhancement by small intestinal submucosa graft

verfasst von: Yves Ozog, Maja L. Konstantinovic, Sofie Verschueren, Federico Spelzini, Dirk De Ridder, Jan Deprest

Erschienen in: International Urogynecology Journal | Ausgabe 4/2009

Einloggen, um Zugang zu erhalten

Abstract

Introduction and hypothesis

To assess the biomechanical properties of full-thickness abdominal wall defects, either using Native tissues, with or without Overlay, and by substitution of the Defect by small intestinal submucosa mesh.

Methods

Seventy-two rats were divided into three groups according to repair method (Native, Overlay or Defect). At 7, 14, 30, and 90 days, six rats were sacrificed to measure tensile strength, collagen ingrowth, and host response.

Results

Explants had comparable strength at 30 days, the majority rupturing at the interface. Afterwards, the Native group was more resistant than both small intestine submucosa (SIS) groups with a more organized fibrotic scar on histology at 90 days.

Conclusions

SIS augmentation of native tissue repair does not increase strength. Replacement of abdominal wall by SIS is equally strong when compared to the SIS-augmented group; however, materials preferably rupture at the site of the implant itself.

Birch C, Fynes MM (2002) The role of synthetic and biological prostheses in reconstructive pelvic floor surgery. Curr Opin Obstet Gynecol 14:527–535PubMedCrossRef

De Ridder D (2008) Should we use meshes in the management of vaginal prolapse. Curr Opin Urol 18:377–382PubMedCrossRef

Winters JC (2006) InteXen tissue processing and laboratory study. Int Urogynecol J Pelvic Floor Dysfunct 17 Suppl 1:S34–S38CrossRef

Badylak SF (2004) Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Transpl Immunol 12:367–377PubMedCrossRef

Schwandner O, Stadler F, Dietl O, Wirsching RP, Fuerst A (2008) Initial experience on efficacy in closure of cryptoglandular and Crohn’s transsphincteric fistulas by the use of the anal fistula plug. Int J Colorectal Dis 23:319–324PubMedCrossRef

Badylak SF, Coffey AC, Lantz GC, Tacker WA, Geddes LA (1994) Comparison of the resistance to infection of intestinal submucosa arterial autografts versus polytetrafluoroethylene arterial prostheses in a dog model. J Vasc Surg 19:465–472PubMed

Helton WS, Fisichella PM, Berger R, Horgan S, Espat NJ, Abcarian H (2005) Short-term outcomes with small intestinal submucosa for ventral abdominal hernia. Arch Surg 140:549–560 (discussion, 560–562)PubMedCrossRef

Jones JS, Rackley RR, Berglund R, Abdelmalak JB, DeOrco G, Vasavada SP (2005) Porcine small intestinal submucosa as a percutaneous mid-urethral sling: 2-year results. BJU Int 96:103–106PubMedCrossRef

Chaliha C, Khalid U, Campagna L, Digesu GA, Ajay B, Khullar V (2006) SIS graft for anterior vaginal wall prolapse repair–a case-controlled study. Int Urogynecol J Pelvic Floor Dysfunct 17:492–497PubMedCrossRef

10.

Alponat A, Lakshminarasappa SR, Yavuz N, Goh PM (1997) Prevention of adhesions by Seprafilm, an absorbable adhesion barrier: an incisional hernia model in rats. Am Surg 63:818–819PubMed

11.

Claerhout F, Verbist G, Verbeken E, Konstantinovic M, De Ridder D, Deprest J (2008) Fate of collagen-based implants used in pelvic floor surgery: a 2-year follow-up study in a rabbit model. Am J Obstet Gynecol 198(94):e1–e6PubMed

12.

Konstantinovic ML, Lagae P, Zheng F, Verbeken EK, De Ridder D, Deprest JA (2005) Comparison of host response to polypropylene and non-cross-linked porcine small intestine serosal-derived collagen implants in a rat model. Bjog 112:1554–1560PubMed

13.

Weber AM, Buchsbaum GM, Chen B et al (2004) Basic science and translational research in female pelvic floor disorders: proceedings of an NIH-sponsored meeting. Neurourol Urodyn 23:288–301PubMedCrossRef

14.

Deprest J, Zheng F, Konstantinovic M et al (2006) The biology behind fascial defects and the use of implants in pelvic organ prolapse repair. Int Urogynecol J Pelvic Floor Dysfunct 17:16–25CrossRef

15.

Maher C, Baessler K, Glazener CM, Adams EJ, Hagen S (2008) Surgical management of pelvic organ prolapse in women: a short version Cochrane review. Neurourol Urodyn 27:3–12PubMedCrossRef

16.

Toosie K, Gallego K, Stabile BE, Schaber B, French S, de Virgilio C (2000) Fibrin glue reduces intra-abdominal adhesions to synthetic mesh in a rat ventral hernia model. Am Surg 66:41–45PubMed

17.

Badylak S, Kokini K, Tullius B, Simmons-Byrd A, Morff R (2002) Morphologic study of small intestinal submucosa as a body wall repair device. J Surg Res 103:190–202PubMedCrossRef

18.

Konstantinovic ML, Pille E, Malinowska M, Verbeken E, De Ridder D, Deprest J (2006) Tensile strength and host response towards different polypropylene implant materials used for augmentation of fascial repair in a rat model. Int Urogynecol J Pelvic Floor Dysfunct 18:619–626PubMed

19.

Movat HZ (1955) Demonstration of all connective tissue elements in a single section; pentachrome stains. AMA Arch Pathol 60:289–295PubMed

20.

Zheng F, Lin Y, Verbeken E et al (2004) Host response after reconstruction of abdominal wall defects with porcine dermal collagen in a rat model. Am J Obstet Gynecol 191:1961–1970PubMedCrossRef

21.

Zheng F, Verbeken E, de Ridder D, Deprest J (2005) Improved surgical outcome by modification of porcine dermal collagen implant in abdominal wall reconstruction in rats. Neurourol Urodyn 24:362–368PubMedCrossRef

22.

Spelzini F, Konstantinovic ML, Guelinckx I et al (2006) Tensile strength and host response towards silk and type I polypropylene implants used for augmentation of fascial repair in a rat model. Gynecol Obstet Invest 63:155–162PubMedCrossRef

23.

Damoiseaux JG, Dopp EA, Calame W, Chao D, MacPherson GG, Dijkstra CD (1994) Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology 83:140–147PubMed

24.

Ko R, Kazacos EA, Snyder S, Ernst DM, Lantz GC (2006) Tensile strength comparison of small intestinal submucosa body wall repair. J Surg Res 135:9–17PubMedCrossRef

25.

Clarke KM, Lantz GC, Salisbury SK, Badylak SF, Hiles MC, Voytik SL (1996) Intestine submucosa and polypropylene mesh for abdominal wall repair in dogs. J Surg Res 60:107–14PubMedCrossRef

26.

Badylak S, Kokini K, Tullius B, Whitson B (2001) Strength over time of a resorbable bioscaffold for body wall repair in a dog model. J Surg Res 99:282–287PubMedCrossRef

27.

Badylak SF (2007) The extracellular matrix as a biologic scaffold material. Biomaterials 28:3587–3593PubMedCrossRef

28.

Hilger WS, Walter A, Zobitz ME, Leslie KO, Magtibay P, Cornella J (2006) Histological and biomechanical evaluation of implanted graft materials in a rabbit vaginal and abdominal model. Am J Obstet Gynecol 195:1826–1831PubMedCrossRef

29.

Stone HH, Fabian TC, Turkleson ML, Jurkiewicz MJ (1981) Management of acute full-thickness losses of the abdominal wall. Ann Surg 193:612–618PubMedCrossRef

Titel: Experimental comparison of abdominal wall repair using different methods of enhancement by small intestinal submucosa graft
verfasst von: Yves Ozog
Maja L. Konstantinovic
Sofie Verschueren
Federico Spelzini
Dirk De Ridder
Jan Deprest
Publikationsdatum: 01.04.2009
Verlag: Springer-Verlag
Erschienen in: International Urogynecology Journal / Ausgabe 4/2009
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-008-0793-6

Neu im Fachgebiet Gynäkologie und Geburtshilfe

23.04.2024 | Medikamente in Schwangerschaft und Stillzeit | Nachrichten

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.

Newsletter bestellen

Springer Medizin

Experimental comparison of abdominal wall repair using different methods of enhancement by small intestinal submucosa graft

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Neu im Fachgebiet Gynäkologie und Geburtshilfe

ICI-Therapie in der Schwangerschaft wird gut toleriert

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

Harnwegsinfektprophylaxe: Es geht auch ohne Antibiotika

Update Gynäkologie

Springer Medizin

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2009

Female sexual function following surgery for stress urinary incontinence: tension-free vaginal versus transobturator tape procedure

St. Mark’s incontinence score for assessment of anal incontinence following obstetric anal sphincter injuries (OASIS)

Pharmacotherapy of urinary incontinence

Stress urinary incontinence after transobturator mesh for cystocele repair

Postoperative erosions of the Mersilene® suburethral sling mesh for antiincontinence surgery

Abdul H. Sultan, Ranee Thakar, Dee E. Fenner (eds): Perineal and Anal Sphincter Trauma

Neu im Fachgebiet Gynäkologie und Geburtshilfe

ICI-Therapie in der Schwangerschaft wird gut toleriert

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

Harnwegsinfektprophylaxe: Es geht auch ohne Antibiotika

Update Gynäkologie