nach oben

International Urogynecology Journal

Erschienen in:

01.08.2013 | Review Article

Interstitial cystitis/bladder pain syndrome: diagnosis and management

verfasst von: I. Offiah, S. B. McMahon, B. A. O’Reilly

Erschienen in: International Urogynecology Journal | Ausgabe 8/2013

Einloggen, um Zugang zu erhalten

Abstract

Introduction and hypothesis

The bladder pain syndrome (BPS) is a spectrum of urological symptoms characterised by bladder pain with typical cystoscopic features. Diagnosis and management of this syndrome may be difficult. There is no evidence-based management approach for the diagnosis or treatment of BPS. The objective of this study was to critically review and summarise the evidence relating to the diagnosis and treatment of the bladder pain syndrome.

Methods

A review of published data on the diagnosis and treatment of the BPS was performed. Our search was limited to English-language articles, on the “diagnosis”, and “management” or “treatment” of “interstitial cystitis” and the “bladder pain syndrome” in “humans.”

Results

Frequency, urgency and pain on bladder filling are the most common symptoms of BPS. All urodynamic volumes are reduced in patients with BPS. Associated conditions include psychological distress, depression, history of sexual assault, irritable bowel syndrome and fibromyalgia. Cystoscopy remains the test for definitive diagnosis, with visualisation of haemorrhage on cystoreduction. A multidisciplinary treatment approach is essential in the management of this condition. Orally administered amitriptyline is an efficacious medical treatment for BPS. Intravesical hyaluronic acid and local anaesthetic, with/without hydrodistension are among new treatment strategies. Sacral or pudendal neuromodulation is effective, minimally invasive and safe. Surgery is reserved for refractory cases.

Conclusions

There remains a paucity of evidence for the diagnosis and treatment of BPS. We encountered significant heterogeneity in the assessment of symptoms, duration of treatment and follow up of patients in our literature review.

Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2003) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society. Urology 61(1):37–49PubMedCrossRef

Hunner GL (1915) A rare type of bladder ulcer in women: report of cases. Boston Med Surg J 172:660–664CrossRef

Hanno P, Lin A, Nordling J, Nyberg L, van Ophoven A, Ueda T et al (2010) Bladder pain syndrome committee of the international consultation on incontinence. Neurourol Urodyn 29(1):191–198PubMedCrossRef

Parsons JK, Parsons CL (2004) The historical origins of interstitial cystitis. J Urol 71(1):20–22CrossRef

Gillenwater JY, Wein AJ (1988) Summary of the national institute of arthritis, diabetes, digestive and kidney diseases workshop on interstitial cystitis, national institutes of health, Bethesda, Maryland. J Urol 140:203–206PubMed

van de Merwe JP, Nordling J, Bouchelouche P et al (2008) Diagnostic criteria, classification, and nomenclature for painful bladder syndrome/interstitial cystitis: an ESSIC proposal. Eur Urol 53(1):60–67PubMedCrossRef

Rovner ES. Interstitial cystitis. Medscape Reference. May 2011. Cited from http://emedicine.medscape.com/article/2055505-overview#a0156

Leppilahti M, Tammela TLJ, Huhtala H, Auvinen A (2002) Prevalence of symptoms related to interstitial cystitis in women: a population based study in Finland. J Urol 168(1):139–143PubMedCrossRef

Rosenberg MT, Hazzard M (2005) Prevalence of interstitial cystitis symptoms in women: a population based study in the primary care office. J Urol 174(6):2231–2234PubMedCrossRef

10.

World Health Organization (1999) 1st International Consultation on Incontinence. Plymbridge Distributors, Plymouth

11.

Ito T, Ueda T, Honma Y, Takei M (2007) Recent trends in patient characteristics and therapeutic choices for interstitial cystitis: analysis of 282 Japanese patients. Int J Urol 14(12):1068–1070PubMedCrossRef

12.

Clemens JQ, Calhoun EA, Litwin MS, Walker-Corkery E, Markossian T, Kusek JW et al (2010) A survey of primary care physician practices in the diagnosis and management of women with interstitial cystitis/painful bladder syndrome. Urology 76(2):323–328PubMedCrossRef

13.

Clemens JQ, Joyce GF, Wise M, Payne CK (2007) Interstitial cystitis and painful bladder syndrome. J Urol 177(6):2042–2049PubMedCrossRef

14.

Pang X, Marchand J, Sant GR, Kream RM, Theorides TC (1995) Increased number of substance P positive nerve fibres in interstitial cystitis. Br J Urol 75(6):744–750PubMedCrossRef

15.

Harrington DS, Fall M, Johansson SL (1990) Interstitial cystitis: bladder mucosa lymphocyte immunophenotyping and peripheral blood flow cystometry analysis. J Urol 144(4):868–871PubMed

16.

Parsons CL (2007) The role of the urinary epithelium in the pathogenesis of interstitial cystitis/prostatitis/urethritis. Urology 69(4):9–16PubMedCrossRef

17.

Keay S, Kleinberg M, Zhang CO, Hise MK, Warren JW (2000) Bladder epithelial cells from patients with interstitial cystitis produce an inhibitor of heparin-binding epidermal growth factor-like growth factor production. J Urol 164(6):2112–2118PubMedCrossRef

18.

Patel R, Calhoun EA, Meenan RT, O’Keeffe Rosetti MC, Kimes T, Clemens JQ (2008) Incidence and clinical characteristics of interstitial cystitis in the community. Int Urogynecol J Pelvic Floor Dysfunct 19(8):1093–1096PubMedCrossRef

19.

Clemens JQ, Bogart LM, Liu K, Pham C, Suttorp M, Berry SH (2011) Perceptions of “urgency” in women with interstitial cystitis/bladder pain syndrome or overactive bladder. Neurol Urodyn 30(3):402–405CrossRef

20.

Shorter B, Lesser M, Moldwin RM, Kushner L (2007) Effect of comestibles on symptoms of interstitial cystitis. J Urol 178(1):145–152PubMedCrossRef

21.

Rackow BW, Novi JM, Arya LA, Pfeifer SM (2009) Interstitial cystitis is an etiology of chronic pelvic pain in young women. J Pediatr Adolesc Gynecol 22(3):181–185PubMedCrossRef

22.

Warren JW, Langenberg P, Greenberg P, Diggs C, Jacobs S, Wesselmann U (2008) Sites of pain from interstitial cystitis/painful bladder syndrome. J Urol 180(4):1373–1377PubMedCrossRef

23.

Paulson JD, Paulson JN (2011) Anterior vaginal wall tenderness (AVWT) as a physical symptom in chronic pelvic pain. JSLS 15(1):6–9PubMedCrossRef

24.

Taneja R (2010) Intravesical lignocaine in the diagnosis of bladder pain syndrome. Int Urogynecol J 21(3):321–324PubMedCrossRef

25.

Altman D, Lundholm C, Milsom I, Peeker R, Fall M, Iliadou AN et al (2011) The genetic and environmental contribution to the occurrence of bladder pain syndrome: an empirical approach in a nationwide population sample. Eur Urol 59(2):280–285PubMedCrossRef

26.

Li GZ, Zhang N, Du P, Yang Y, Wu SL, Xiao YX et al (2010) Risk factors for interstitial cystitis/painful bladder syndrome in patients with lower urinary tract symptoms: a Chinese multi-centre study. Chin Med J 123(20):2842–2846PubMed

27.

Tettamanti G, Nyman-Illadou A, Pedersen NL, Bellocco R, Milsom I, Altman D (2011) Influence of smoking, coffee, and tea consumption on bladder pain syndrome in female twins. Urology 77(6):1313–1317PubMedCrossRef

28.

Droz J, Howard FM (2011) Use of the short-form McGill pain questionnaire as a diagnostic tool in women with chronic pelvic pain. J Minim Invasive Gynecol 18(2):211–217PubMedCrossRef

29.

Nickel JC, Shoskes D, Irvine-Bird K (2009) Clinical phenotyping of women with interstitial cystitis/painful bladder syndrome: a key to classification and potentially improved management. J Urol 182(1):155–160PubMedCrossRef

30.

Fenton BW, Palmieri PA, Fanning J (2008) Receiver operating characteristic curves of symptom scores in the diagnosis of interstitial cystitis/painful bladder syndrome. J Minim Invasive Gynecol 15(5):601–604PubMedCrossRef

31.

Kushner L, Moldwin RM (2006) Efficacy of questionnaires used to screen for interstitial cystitis. J Urol 176(2):587–592PubMedCrossRef

32.

Brewer ME, White WM, Klein FA, Waters WB (2007) Validity of pelvic pain, urgency, and frequency questionnaire in patients with interstitial cystitis/painful bladder syndrome. Urology 70(4):646–649PubMedCrossRef

33.

Fukui Y, Kato M, Inoue Y, Matsubara A, Itoh K (2009) A metabonomic approach identifies human urinary phenylacetyglutamine as a novel marker of interstitial cystitis. J Chromatogr B Analyt Technol Biomed Life Sci 877(30):3806–3812PubMedCrossRef

34.

Liu HT, Tyagi P, Chancellor MB, Kuo HC (2010) Urinary nerve growth factor but not prostaglandin E2 increases in patients with interstitial cystitis/bladder pain syndrome and detrusor overactivity. BJU Int 106(11):1681–1685PubMedCrossRef

35.

Jacobs BL, Smaldone MC, Tyagi V, Philips BJ, Jackman SV, Leng WW et al (2010) Increased nerve growth factor in neurogenic overactive bladder and interstitial cystitis patients. Can J Urol 17(1):4989–4994PubMed

36.

Alp BF, Akyol I, Adayener C, Senkul T, Gultepe M, Baykal K et al (2009) The significance of potassium chloride sensitivity test and urinary uronic acid level in the diagnosis of chronic pelvic pain syndrome. Int Urol Nephrol 41(3):483–489PubMedCrossRef

37.

Kuromitsu S, Yokota H, Hiramoto M, Morita S, Mita H, Yamada T (2008) Increased concentration of neutrophil elastase in urine from patients with interstitial cystitis. Scand J Urol Nephrol 42(5):455–461PubMedCrossRef

38.

Daha LK, Lazar D, Simak R, Pflüger H (2007) Is there a relation between urinary interleukin-6 levels and symptoms before and after intra-vesical glycosaminoglycan substitution therapy in patients with bladder pain syndrome/interstitial cystitis? Int Urogynecol J Pelvic Floor Dysfunct 18(12):1449–1452PubMedCrossRef

39.

Hosseini A, Ehren I, Wiklund NP (2004) Nitric oxide as an objective marker for evaluation of treatment response in patients with classic interstitial cystitis. J Urol 172(6 Pt 1):2261–2265PubMedCrossRef

40.

Sastry DN, Hunter KM, Whitemore KE (2010) Urodynamic testing and interstitial cystitis/painful bladder syndrome. Int Urogynecol J 21(2):157–161PubMedCrossRef

41.

Kim SH, Kim TB, Kim SW, Oh SJ (2009) Urodynamic findings of the painful bladder syndrome/interstitial cystitis: a comparison with idiopathic overactive bladder. J Urol 181(6):2550–2554PubMedCrossRef

42.

Sahinkanat T, Guven A, Ekerbicer H, Aral M (2008) Prevalence of positive potassium sensitivity test which is an indicator of bladder epithelial permeability dysfunction in a fixed group of Turkish women. Urol Int 80(1):52–56PubMedCrossRef

43.

Sairanen J, Tammela TL, Leppilahti M, Onali M, Forsell T, Ruutu M (2007) Potassium sensitivity test (PST) as a measurement of treatment efficacy of painful bladder syndrome/interstitial cystitis: a prospective study with cyclosporine a and pentosan polysulfate sodium. Neurol Urodyn 26(2):267–270CrossRef

44.

Parsons CL, Greenberger M, Gabal L, Bidair M, Barme G (1998) The role of urinary potassium in the pathogenesis and diagnosis of interstitial cystitis. J Urol 159(6):186206CrossRef

45.

Brunstein R, Shapiro E, Kaye J & Moldwin R (2008) The role of cystoscopy in the diagnosis of Hunner’s ulcer disease. J Urol 180(4):1383–1386CrossRef

46.

Aihara K, Hiayama A, Tanaka N, Fujimoto K, Yoshida K, Hirao Y (2009) Hydrodistension under local anesthesia for patients with suspected painful bladder syndrome/interstitial cystitis: safety, diagnostic potential and therapeutic efficacy. Int J Urol 16(12):947–952PubMedCrossRef

47.

Geurts N, Van Dyck J, Wyndaele JJ (2011) Bladder pain syndrome: do the different morphological and cystoscopic features correlate? Scand J Neurol Urodyn 45(1):20–23CrossRef

48.

Shie JH, Kuo HC (2011) Higher levels of cell apoptosis and abnormal E-cadherin expression in the urothelium are associated with inflammation in patients with interstitial cystitis/painful bladder syndrome. BJU 108(2):136–141

49.

Hauser PJ, Dozmorov MG, Bane BL, Slobodov G, Culkin DJ, Hurst RE (2008) Abnormal expression of differentiation related proteins and proteoglycan core proteins in the urothelium of patients with interstitial cystitis. J Urol 179(2):764–769PubMedCrossRef

50.

Kutlu O, Akkaya E, Koksal IT, Bassorgun IC, Ciftcioglu MA, Sanlioglu S et al (2010) Importance of TNF-related apoptosis-inducing ligand in pathogenesis of interstitial cystitis. Int Urol Nephrol 42(2):393–399PubMedCrossRef

51.

Gamper M, Viereck V, Geissbúhler V, Eberhard J, Binder J, Moll C et al (2009) Gene expression profile of bladder tissue of patients with ulcerative interstitial cystitis. BMC Genomics 10:199PubMedCrossRef

52.

Koskela LR, Thiel T, Ehrén I, De Verdier PJ, Wiklund NP (2008) Localization and expression of inducible nitric oxide synthase in biopsies from patients with interstitial cystitis. J Urol 180(2):737–741PubMedCrossRef

53.

Liu HT, Tyagi P, Chancellor MB, Kuo HC (2009) Urinary nerve growth factor level is increased in patients with interstitial cystitis/bladder pain syndrome and decreased in responders to treatment. BJU Int 104(10):1476–1481PubMedCrossRef

54.

Tseng-Rogenski S, Liebert M (2009) Interleukin-8 is essential for normal urothelial cell survival. Am J Physiol Renal Physiol 297(3):816–821CrossRef

55.

Saban R, Saban MR, Maier J, Fowler B, Tengowski M, Davis CA et al (2008) Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients. Am J Physiol Renal Physiol 295(6):1613–1623CrossRef

56.

Canter MP, Graham CA, Heit MH, Blackwell LS, Wilkey DW, Klein JB et al (2008) Proteomic techniques identify urine proteins that differentiate patients with interstitial cystitis from asymptomatic control subjects. Am J Obstet Gynecol 198(5):553, e1–e6PubMedCrossRef

57.

Yamada T, Nishimura M, Mita H (2007) Increased number of apoptotic endothelial cells in bladder of interstitial cystitis patients. World J Urol 25(4):407–413PubMedCrossRef

58.

Zeng Y, Wu XX, Homma Y, Yoshimura N, Iwaki H, Kageyama S et al (2007) Uroplakin III-dlta4 messenger RNA as a promising marker to identify nonulcerative interstitial cystitis. J Urol 178(4):1322–1327PubMedCrossRef

59.

Parsons CL, Stein P, Zupkas P, Chenoweth M, Argade SP, Proctor JG et al (2007) Defective Tamm-Horsfall protein in patients with interstitial cystitis. J Urol 178(6):2665–2670PubMedCrossRef

60.

Watkins KE, Eberhart N, Hilton L, Suttorp KJ, Hepner KA, Clemens JQ et al (2011) Depressive disorders and panic attacks in women with bladder pain syndrome/interstitial cystitis: a population-based sample. Gen Hosp Psychiatry 33(2):143–149PubMedCrossRef

61.

Clemens JQ, Brown SO, Calhoun EA (2008) Mental health diagnoses in patients with interstitial cystitis/painful bladder syndrome and chronic pelvic pain syndrome: a case study. J Urol 180(4):1378–1382PubMedCrossRef

62.

Bogart LM, Suttorp MJ, Elliott MN, Clemens JQ, Berry SH (2011) Prevalence and correlates of sexual dysfunction among women with bladder pain syndrome/interstitial cystitis. Urology 77(3):576–580PubMedCrossRef

63.

Peters KM, Killinger KA, Carrico DJ, Ibrahim IA, Diokno AC, Graziottin A (2007) Sexual function and sexual distress in women with interstitial cystitis: a case–control study. Urology 70(3):543–547PubMedCrossRef

64.

Tietjen GE, Brandes JL, Peterlin BL, Eloff A, Dafer RM, Stein MR et al (2010) Childhood maltreatment and migraines (part III). Association with comorbid pain conditions. Headache 50(1):42–51PubMedCrossRef

65.

Clemens JQ, Meenan RT, O’Keeffe Rosetti MC, Kimes TA, Calhoun EA (2008) Case–control study of medical comorbidities in women with interstitial cystitis. J Urol 179(6):2222–2225PubMedCrossRef

66.

Bassaly R, Tidwell N, Bertolino S, Hoyte L, Downes K, Hart S (2011) Myofascial pain and pelvic floor dysfunction in patients with interstitial cystitis. Int Urogynecol J 22(4):413–418PubMedCrossRef

67.

Nickel JC, Tripp DA, Pontari M, Moldwin R, Mayer R, Carr LK et al (2010) Interstitial cystitis/painful bladder syndrome and associated medical conditions with an emphasis on irritable bowel syndrome, fibromyalgia and chronic fatigue syndrome. J Urol 184(4):1358–1363PubMedCrossRef

68.

Peters KM, Carrico DJ, Kalinowski SE, Ibrahim IA, Diokno AC (2007) Prevalence of pelvic floor dysfunction in patients with interstitial cystitis. Urology 70(1):16–18PubMedCrossRef

69.

Nickel JC, Tripp D, Teal V, Propert KJ, Burks D, Foster HE et al (2007) Sexual function is a determinant of poor quality of life for women with treatment refractory interstitial cystitis. J Urol 177(5):1832–1836PubMedCrossRef

70.

Ginting JV, Tripp DA, Nickel JC, Fitzgerald MP, Mayer R (2011) Spousal support decreases the negative impact of pain on mental quality of life in women with interstitial cystitis/painful bladder syndrome. BJU Int 108(5):713–717PubMed

71.

El Khoudary SR, Talbott EO, Bromberger JT, Chang CC, Songer TJ, Davis EL (2009) Severity of interstitial cystitis symptoms and quality of life in female patients. J Women Health (Larchmt) 18(9):1361–1368CrossRef

72.

Ingber MS, Peters KM, Killinger KA, Carrico DJ, Ibrahim IA, Diokno AC (2008) Dilemmas in diagnosing pelvic pain: multiple pelvic surgeries common in women with interstitial cystitis. Int Urogynecol J Pelvic Floor Dysfunct 19(3):341–345PubMedCrossRef

73.

Stanford E, McMurphy C (2007) There is a low incidence of recurrent bacteriuria in painful bladder syndrome/interstitial cystitis patients followed longitudinally. Int Urogynecol J Pelvic Floor Dysfunct 18(5):551–554PubMedCrossRef

74.

Abrahms P, Cardozo L, Khoury S, Wein A. Incontinence. 4th Edition 2009. 4th International Consultation on Incontinence. July 2008.

75.

Hanno PM, Burks DA, Clemens JQ, Dmochowski RR, Erickson D, Fitzgerald P et al (2011) Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. American Urological Association (AUA). J Urol 185(6):2162–2170PubMedCrossRef

76.

Carrico DJ, Peters KM, Diokno AC (2008) Guided imagery for women with interstitial cystitis: results of a prospective, randomized controlled pilot study. J Altern Complement Med 14(1):53–60PubMedCrossRef

77.

Hertle L, van Ophoven A (2010) Long-term results of amitriptyline treatment for interstitial cystitis. Aktuelle Urol 41 [Suppl 1]:S61–S65PubMedCrossRef

78.

Lee JW, Han DY, Jeong HJ (2010) Bladder pain syndrome treated with triple therapy with gabapentin, amitriptyline, and a non-steroidal anti-inflammatory drug. Int Neurourol J 14(4):256–260PubMedCrossRef

79.

Seshadri P, Emerson L, Morales A (1994) Cimetidine in the treatment of interstitial cystitis. Urology 44(4):614–616PubMedCrossRef

80.

Daha LK, Lazar D, Simak R, Pfluger H (2008) The effects of intravesical pentosanpolysulfate treatment on the symptoms of patients with bladder pain syndrome/interstitial cystitis: preliminary results. Int Urogynecol J Pelvic Floor Dysfunct 19(7):987–990PubMedCrossRef

81.

Davis EL, El Khoudary SR, Talbott EO, Davis J, Regan LJ (2008) Safety and efficacy of the use of intravesical and oral pentosan polysulfate sodium for interstitial cystitis: a randomized double-blind clinical trial. J Urol 179(1):177–185PubMedCrossRef

82.

Engelhardt PF, Morakis N, Daha LK, Esterbauer B, Riedl CR (2011) Long-term results of intravesical hyaluronan therapy in bladder pain syndrome/interstitial cystitis. Int Urogynecol J 22(4):401–405PubMedCrossRef

83.

Cervigni M, Natale F, Nasta L, Padoa A, Voi RL, Porru D (2008) A combined intravesical therapy with hyaluronic acid and chondroitin for refractory painful bladder syndrome/interstitial cystitis. Int Urogynecol J Pelvic Floor Dysfunct 19(7):943–947PubMedCrossRef

84.

Nickel JC, Hanno P, Kumar K, Thomas H (2012) Second multicenter, randomized, double-blind parallel-group evaluation of effectiveness and safety of intravesical sodium chondroitin sulfate compared with inactive vehicle control in subjects with interstitial cystitis/bladder pain syndrome. Urology 79(6):1220–1224PubMedCrossRef

85.

Kuo HC, Chancellor MB (2009) Comparison of intravesical botulinum toxin type a injections plus hydrodistension with hydrodistension alone for the treatment of refractory interstitial cystitis/painful bladder syndrome. BJU Int 104(5):657–661PubMedCrossRef

86.

Nickel JC, Moldwin R, Lee S, Davis EL, Henry RA, Wyllie MG (2009) Intravesical alkalinized lidocaine (PSD597) offers sustained relief from symptoms of interstitial cystitis and painful bladder syndrome. BJU Int 103(7):910–918PubMedCrossRef

87.

Cox M, Klutke JJ, Klutke CG (2009) Assessment of patient outcomes following submucosal injection of triamcinolone for treatment of Hunner’s ulcer subtype interstitial cystitis. Can J Urol 16(2):4536–4540PubMed

88.

Chuang YC, Lee WC, Lee WC, Chiang PH (2009) Intravesical liposome versus oral pentosan polysulfate for interstitial cystitis/painful bladder syndrome. J Urol 182(4):1393–1400PubMedCrossRef

89.

Stav K, Beberashvili I, Lindner A, Leibovici D (2012) Predictors of response to intravesical-sulfoxide cocktail in patients with interstitial cystitis. Urology 80(1):61–65PubMedCrossRef

90.

Propert KJ, Mayer R, Nickel JC, Payne CK, Peters KM, Teal V et al (2008) Followup of patients with interstitial cystitis responsive to treatment with intravesical bacillus Calmette-Guerin or placebo. J Urol 179(2):552–555PubMedCrossRef

91.

Peng CH, Kuo HC (2007) Multiple intravesical instillations of low dose resiniferatoxin in the treatment of refractory interstitial cystitis. Urol Int 78(1):78–81PubMedCrossRef

92.

Barbalias GA, Liatsikos EN, Athanasopoulos A, Nikiforidis G (2000) Interstitial cystitis: bladder training with intravesical oxybutynin. J Urol 163(6):1818–1822PubMedCrossRef

93.

Tanaka T, Nitta Y, Morimoto K, Nishikawa N, Nishihara C, Tamada S et al (2011) Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan. BMC Urol 24:11CrossRef

94.

Sairanen J, Tammela TL, Leppilahti M, Multanen M, Paananen I, Lehtoranta K et al (2005) Cyclosporine A and pentosan polysulfate sodium for the treatment of interstitial cystitis: a randomized comparative study. J Urol 174(6):2235–2238PubMedCrossRef

95.

Hsieh CH, Chang ST, Hsieh CJ, Hsu CS, Chang HC, Lin YH (2008) Treatment of interstitial cystitis with hydrodistension and bladder training. Int Urogynecol J Pelvic Floor Dysfunct 19(10):1379–1384PubMedCrossRef

96.

Ghazwani YQ, Elkelini MS, Hassouna MM (2011) Efficacy of sacral neuromodulation in treatment of bladder pain syndrome: long-term follow up. Neurourol Urodyn 30(7):1271–1275PubMed

97.

Gajewski JB, Al-Zahrani AA (2011) The long-term efficacy of sacral neuromodulation in the management of intractable cases of bladder pain syndrome: 14 years of experience in one centre. BJU Int 107(8):1258–1264PubMedCrossRef

98.

Zabihi N, Mourtzinos A, Maher MG, Raz S, Rodriguez LV (2008) Short-term results of bilateral S2-S4 sacral neuromodulation for the treatment of refractory interstitial cystitis, painful bladder syndrome, and chronic pelvic pain. Int Urogynecol J Pelvic Floor Dysfunct 19(4):553–557PubMedCrossRef

99.

Peters KM, Feber KM, Bennett RC (2007) A prospective, single-blind, randomized crossover trial of sacral vs pudendal nerve stimulation for interstitial cystitis. BJU Int 100(4):835–839PubMedCrossRef

100.

O’Reilly BA, Dwyer PL, Hawthorne G, Cleaver S, Thomas E, Rosmilia A et al (2004) Transdermal posterior tibial nerve laser therapy is not effective in women with interstitial cystitis. J Urol 172(5 Pt 1):1880–1883PubMedCrossRef

101.

Kochakarn W, Lertsithichai P, Pummangura W (2007) Bladder substitution by ileal neobladder for women with interstitial cystitis. Int Braz J Urol 33(4):486–492PubMedCrossRef

102.

Rössberger J, Fall M, Jonsson O, Peeker R (2007) Long-term results of reconstructive surgery in patients with bladder pain syndrome/interstitial cystitis: sub-typing is imperative. Urology 70(4):638–642PubMedCrossRef

Titel: Interstitial cystitis/bladder pain syndrome: diagnosis and management
verfasst von: I. Offiah
S. B. McMahon
B. A. O’Reilly
Publikationsdatum: 01.08.2013
Verlag: Springer London
Erschienen in: International Urogynecology Journal / Ausgabe 8/2013
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-013-2057-3

Neu im Fachgebiet Gynäkologie und Geburtshilfe

17.04.2024 | Postoperative nausea and vomiting | Nachrichten

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.

Newsletter bestellen

Springer Medizin

Interstitial cystitis/bladder pain syndrome: diagnosis and management

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Neu im Fachgebiet Gynäkologie und Geburtshilfe

Hochrisiko-Eingriffe für postoperative Übelkeit

Adjuvante Brustkrebstherapie: Doppelt hält besser

Manche Gestagene können das Risiko für Meningeome erhöhen

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Gynäkologie

Springer Medizin

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 8/2013

The urethra is a reliable witness: simplifying the diagnosis of stress urinary incontinence. Reply to Wagenlehner et al.

Small-bowel obstruction and bladder injury due to retropubic sling malposition in the peritoneal cavity

The effect of pelvic organ prolapse severity on improvement in overactive bladder symptoms after pelvic reconstructive surgery

Can urodynamic stress incontinence be diagnosed by ultrasound?

Prospective study of an ultra-lightweight polypropylene Y mesh for robotic sacrocolpopexy

Ray Lee, 1931–2012: surgeon, teacher, mentor, friend

Neu im Fachgebiet Gynäkologie und Geburtshilfe

Hochrisiko-Eingriffe für postoperative Übelkeit

Adjuvante Brustkrebstherapie: Doppelt hält besser

Manche Gestagene können das Risiko für Meningeome erhöhen

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Gynäkologie