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Erschienen in: International Urogynecology Journal 8/2014

01.08.2014 | Original Article

Women’s perspective: intra-detrusor botox versus sacral neuromodulation for overactive bladder symptoms after unsuccessful anticholinergic treatment

verfasst von: Pooja Balchandra, Lynne Rogerson

Erschienen in: International Urogynecology Journal | Ausgabe 8/2014

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Abstract

Introduction and hypothesis

Comprehension of women’s perspective and reasons for their choice between intra-detrusor botox (botox) and sacral neuromodulation (SNM) after failed anticholinergic treatment for overactive bladder syndrome (OAB) have not been evaluated and reported in the literature. Our voluntary service evaluation survey aimed to determine reasons behind individual patient choice.

Methods

All women were counseled in detail regarding the two treatment options available after failed anticholinergic treatment as per the hospital trust policy. Once the decision-making process was completed, they were asked to highlight one or more of the 12 questions within the survey that influenced their decision-making process.

Results

Fifty patients, with a mean age of 61.66 years (range 38–82 years) participated in our voluntary survey. Seventy-four per cent chose Botox and 26 % chose SNM. In the botox group 54.05 % disliked the thought of a foreign body in the back with SNM; 45.94 % quoted shorter waiting times and 43.24 % said that the quicker onset of benefit (within 3–5 days) with botox compared with SNM (up to 2 weeks) helped to influence their decision towards botox. In the SNM group 61.53 % were averse to the potential need for botox to be repeated at variable intervals; 46.15 % chose SNM to avoid the risk of urinary retention associated with botox.

Conclusion

The botox group seemed more likely to need quicker results with easy access to the treatment modality, whilst the SNM group seemed keener to focus on a more permanent option with a known interval for the repeat procedure. The difference in patient choice was found to be statistically significant.
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Literatur
1.
Zurück zum Zitat Arnold J, McLeod N, Thani-Gasalam R, Rashid P (2012) Overactive bladder syndrome—management and treatment options. Aust Fam Physician 41(11):878–883PubMed Arnold J, McLeod N, Thani-Gasalam R, Rashid P (2012) Overactive bladder syndrome—management and treatment options. Aust Fam Physician 41(11):878–883PubMed
2.
Zurück zum Zitat Dmochowski R, Chapple C, Nitti VW et al (2010) Efficacy and safety of onabotulinumtoxinA for idiopathic overactive bladder: a double-blind, placebo controlled, randomized, dose ranging trial. J Urol 184(6):2416–2422PubMedCrossRef Dmochowski R, Chapple C, Nitti VW et al (2010) Efficacy and safety of onabotulinumtoxinA for idiopathic overactive bladder: a double-blind, placebo controlled, randomized, dose ranging trial. J Urol 184(6):2416–2422PubMedCrossRef
3.
Zurück zum Zitat Giarenis I, Cardozo L (2013) Management of refractory overactive bladder. Minerva Ginecol 65(1):41–52PubMed Giarenis I, Cardozo L (2013) Management of refractory overactive bladder. Minerva Ginecol 65(1):41–52PubMed
4.
Zurück zum Zitat Abrams P, Blaivas JG, Fowler CJ et al (2003) The role of neuromodulation in the management of urinary urge incontinence. BJU Int 91(4):355–359PubMedCrossRef Abrams P, Blaivas JG, Fowler CJ et al (2003) The role of neuromodulation in the management of urinary urge incontinence. BJU Int 91(4):355–359PubMedCrossRef
5.
Zurück zum Zitat Kantartzis K, Shepherd J (2012) Sacral neuromodulation and intravesical botulinum toxin for refractory overactive bladder. Curr Opin Obstet Gynecol 24(5):331–336PubMedCrossRef Kantartzis K, Shepherd J (2012) Sacral neuromodulation and intravesical botulinum toxin for refractory overactive bladder. Curr Opin Obstet Gynecol 24(5):331–336PubMedCrossRef
6.
7.
Zurück zum Zitat Chapple C, Sievert KD, MacDiarmid S et al (2013) OnabotulinumtoxinA 100 U significantly improves all idiopathic overactive bladder symptoms and quality of life in patients with overactive bladder and urinary incontinence: a randomised, double-blind, placebo-controlled trial. Eur Urol 64(2):249–256PubMedCrossRef Chapple C, Sievert KD, MacDiarmid S et al (2013) OnabotulinumtoxinA 100 U significantly improves all idiopathic overactive bladder symptoms and quality of life in patients with overactive bladder and urinary incontinence: a randomised, double-blind, placebo-controlled trial. Eur Urol 64(2):249–256PubMedCrossRef
8.
Zurück zum Zitat Digesu GA, Panayi D, Hendricken C, Camarata M, Fernando R, Khullar V (2011) Women’s perspective of botulinum toxin treatment for overactive bladder symptoms. Int Urogynecol J 22(4):425–431PubMedCrossRef Digesu GA, Panayi D, Hendricken C, Camarata M, Fernando R, Khullar V (2011) Women’s perspective of botulinum toxin treatment for overactive bladder symptoms. Int Urogynecol J 22(4):425–431PubMedCrossRef
9.
Zurück zum Zitat Kalsi V, Apostolidis A, Gonzales G, Elneil S, Dasgupta P, Fowler C (2008) Early effect on the overactive bladder symptoms following botulinum neurotoxin type A injections for detrusor overactivity. Eur Urol 54(1):181–187PubMedCrossRef Kalsi V, Apostolidis A, Gonzales G, Elneil S, Dasgupta P, Fowler C (2008) Early effect on the overactive bladder symptoms following botulinum neurotoxin type A injections for detrusor overactivity. Eur Urol 54(1):181–187PubMedCrossRef
10.
Zurück zum Zitat Khan S, Kessler TM, Apostolidis A et al (2009) What a patient with refractory idiopathic detrusor overactivity should know about botulinum neurotoxin type a injection. J Urol 181(4):1773–1778PubMedCrossRef Khan S, Kessler TM, Apostolidis A et al (2009) What a patient with refractory idiopathic detrusor overactivity should know about botulinum neurotoxin type a injection. J Urol 181(4):1773–1778PubMedCrossRef
11.
Zurück zum Zitat Arlandis S, Castro D, Errando C et al (2011) Cost-effectiveness of sacral neuromodulation compared to botulinum neurotoxin a or continued medical management in refractory overactive bladder. Value Health 14(2):219–228PubMedCrossRef Arlandis S, Castro D, Errando C et al (2011) Cost-effectiveness of sacral neuromodulation compared to botulinum neurotoxin a or continued medical management in refractory overactive bladder. Value Health 14(2):219–228PubMedCrossRef
12.
Zurück zum Zitat Cameron AP, Anger JT, Madison R, Saigal CS, Clemens JQ; Urologic Diseases in America Project (2013) Battery explantation after sacral neuromodulation in the Medicare population. Neurourol Urodyn 32(3):238–241PubMedCrossRef Cameron AP, Anger JT, Madison R, Saigal CS, Clemens JQ; Urologic Diseases in America Project (2013) Battery explantation after sacral neuromodulation in the Medicare population. Neurourol Urodyn 32(3):238–241PubMedCrossRef
13.
Zurück zum Zitat Jadav AM, Wadhawan H, Jones GL, Wheldon LW, Radley SC, Brown SR (2013) Does sacral nerve stimulation improve global pelvic function in women? Colorectal Dis 15(7):848–857PubMedCrossRef Jadav AM, Wadhawan H, Jones GL, Wheldon LW, Radley SC, Brown SR (2013) Does sacral nerve stimulation improve global pelvic function in women? Colorectal Dis 15(7):848–857PubMedCrossRef
Metadaten
Titel
Women’s perspective: intra-detrusor botox versus sacral neuromodulation for overactive bladder symptoms after unsuccessful anticholinergic treatment
verfasst von
Pooja Balchandra
Lynne Rogerson
Publikationsdatum
01.08.2014
Verlag
Springer London
Erschienen in
International Urogynecology Journal / Ausgabe 8/2014
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-014-2360-7

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