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Osteoporosis International

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01.10.2011 | Review

Relationship between serum RANKL and RANKL in bone

verfasst von: D. M. Findlay, G. J. Atkins

Erschienen in: Osteoporosis International | Ausgabe 10/2011

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Abstract

It is now well accepted that the molecule receptor activator of NFκB ligand (RANKL) and osteoprotegerin play key roles in regulating physiological and pathological bone turnover. There are a large number of published reports of circulating RANKL levels in both health and pathology. However, interpretation of these data has been elusive, and the relationship between circulating RANKL and RANKL levels in bone is still not clear. This review explores this subject, documenting the possible origins of circulating RANKL and suggesting additional information that is required before serum RANKL levels can provide useful diagnostic or research information.

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Titel: Relationship between serum RANKL and RANKL in bone
verfasst von: D. M. Findlay
G. J. Atkins
Publikationsdatum: 01.10.2011
Verlag: Springer-Verlag
Erschienen in: Osteoporosis International / Ausgabe 10/2011
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-011-1740-9

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