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Experimental Brain Research

Erschienen in:

01.06.2009 | Review

Migraine: where and how does the pain originate?

verfasst von: Karl Messlinger

Erschienen in: Experimental Brain Research | Ausgabe 1/2009

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Abstract

Migraine is a complex neurological disease with a genetic background. Headache is the most prominent and clinically important symptom of migraine but its origin is still enigmatic. Numerous clinical, histochemical, electrophysiological, molecular and genetical approaches form a puzzle of findings that slowly takes shape. The generation of primary headaches like migraine pain seems to be the consequence of multiple pathophysiological changes in meningeal tissues, the trigeminal ganglion, trigeminal brainstem nuclei and descending inhibitory systems, based on specific characteristics of the trigeminovascular system. This contribution reviews the current discussion of where and how the migraine pain may originate and outlines the experimental work to answer these questions.

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Titel: Migraine: where and how does the pain originate?
verfasst von: Karl Messlinger
Publikationsdatum: 01.06.2009
Verlag: Springer-Verlag
Erschienen in: Experimental Brain Research / Ausgabe 1/2009
Print ISSN: 0014-4819
Elektronische ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-009-1756-y

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Migraine: where and how does the pain originate?

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Leitlinien kompakt für die Neurologie

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