Skip to main content
Erschienen in: Neuroradiology 12/2003

01.12.2003 | Diagnostic Neuroradiology

Magnetic resonance imaging of sequelae of central pontine myelinolysis in chronic alcohol abusers

verfasst von: Akira Uchino, Takefumi Yuzuriha, Masaru Murakami, Koichi Endoh, Shigeto Hiejima, Hiroshi Koga, Sho Kudo

Erschienen in: Neuroradiology | Ausgabe 12/2003

Einloggen, um Zugang zu erhalten

Abstract

Central pontine myelinolysis (CPM) is one of the serious neurological complications of alcoholism. This study evaluated magnetic resonance images of sequelae of CPM. Approximately 600 alcoholic patients were examined by a 1.0-T magnetic resonance imaging device, and 11 patients were retrospectively found to have a central pontine lesion, a presumed sequela of CPM. The lesions had various shapes and most were cavitary. In 3 of the 11 patients bilateral symmetrical oval lesions were faintly visible in the middle cerebellar peduncles. These middle cerebellar peduncular lesions were diagnosed as having Wallerian degeneration of the pontocerebellar tract secondary to CPM.
Literatur
1.
Zurück zum Zitat Adams RD, Victor M, Mancall EL (1959) Central pontine myelinolysis. A hitherto undescribed disease occurring in alcoholic and malnourished patients. Arch Neurol Psychiatry 81:154–172 Adams RD, Victor M, Mancall EL (1959) Central pontine myelinolysis. A hitherto undescribed disease occurring in alcoholic and malnourished patients. Arch Neurol Psychiatry 81:154–172
2.
Zurück zum Zitat Miller GM, Baker HL Jr, Okazaki H, Whisnant JP (1988) Central pontine myelinolysis and its imitators: MR findings. Radiology 168:795–802PubMed Miller GM, Baker HL Jr, Okazaki H, Whisnant JP (1988) Central pontine myelinolysis and its imitators: MR findings. Radiology 168:795–802PubMed
3.
Zurück zum Zitat Gocht A, Colmant HJ (1987) Central pontine and extrapontine myelinolysis: a report of 58 cases. Clin Neuropathol 6:262–270PubMed Gocht A, Colmant HJ (1987) Central pontine and extrapontine myelinolysis: a report of 58 cases. Clin Neuropathol 6:262–270PubMed
4.
Zurück zum Zitat Koci TM, Chiang F, Chow P, Wang A, Chiu LC, Itabashi H, Mehringer CM (1990) Thalamic extrapontine lesions in central pontine myelinolysis. Am J Neuroradiol 11:1229–1233PubMed Koci TM, Chiang F, Chow P, Wang A, Chiu LC, Itabashi H, Mehringer CM (1990) Thalamic extrapontine lesions in central pontine myelinolysis. Am J Neuroradiol 11:1229–1233PubMed
5.
Zurück zum Zitat Bourgouin PM, Chalk C, Richardson J, Duang H, Vezina JL (1995) Subcortical white matter lesions in osmotic demyelination syndrome. Am J Neuroradiol 16:1495–1497PubMed Bourgouin PM, Chalk C, Richardson J, Duang H, Vezina JL (1995) Subcortical white matter lesions in osmotic demyelination syndrome. Am J Neuroradiol 16:1495–1497PubMed
6.
Zurück zum Zitat Mangat KS, Sherlala K (2002) Cerebellar peduncle myelinolysis: case report. Neuroradiology 44:768–769CrossRefPubMed Mangat KS, Sherlala K (2002) Cerebellar peduncle myelinolysis: case report. Neuroradiology 44:768–769CrossRefPubMed
7.
Zurück zum Zitat Ohuchi T, Kuru Y, Ri K, Hayashi T, Yasuda R, Honda S, Maki S (1998) Wallerian degeneration of the pontocerebellar tracts and cerebellar atrophy following pontine bleeding. Rinsho Hoshasen 43:449–455 Ohuchi T, Kuru Y, Ri K, Hayashi T, Yasuda R, Honda S, Maki S (1998) Wallerian degeneration of the pontocerebellar tracts and cerebellar atrophy following pontine bleeding. Rinsho Hoshasen 43:449–455
8.
Zurück zum Zitat Gallucci M, Amicarelli I, Rossi A, Stratta P, Masciocchi C, Zobel BB, Casacchia M, Passariello R (1989) MR imaging of white matter lesions in uncomplicated chronic alcoholism. J Comput Assist Tomogr 13:395–398PubMed Gallucci M, Amicarelli I, Rossi A, Stratta P, Masciocchi C, Zobel BB, Casacchia M, Passariello R (1989) MR imaging of white matter lesions in uncomplicated chronic alcoholism. J Comput Assist Tomogr 13:395–398PubMed
9.
Zurück zum Zitat Ho VB, Fitz CR, Yoder CC, Geyer CA (1993) Resolving MR features in osmotic myelinolysis (central pontine and extrapontine myelinolysis). Am J Neuroradiol 14:163–167PubMed Ho VB, Fitz CR, Yoder CC, Geyer CA (1993) Resolving MR features in osmotic myelinolysis (central pontine and extrapontine myelinolysis). Am J Neuroradiol 14:163–167PubMed
10.
Zurück zum Zitat Korogi Y, Takahashi M, Shinzato J, Sakamoto Y, Mitsuzaki K, Hirai T, Yoshizumi K (1993) MR findings in two presumed cases of mild central pontine myelinolysis. Am J Neuroradiol 14:651–654PubMed Korogi Y, Takahashi M, Shinzato J, Sakamoto Y, Mitsuzaki K, Hirai T, Yoshizumi K (1993) MR findings in two presumed cases of mild central pontine myelinolysis. Am J Neuroradiol 14:651–654PubMed
11.
Zurück zum Zitat Yuh WTC, Simonson TM, D'Alessandro MP, Smith KS, Hunsicker LG (1995) Temporal changes of MR findings in central pontine myelinolysis. Am J Neuroradiol 16:975–977PubMed Yuh WTC, Simonson TM, D'Alessandro MP, Smith KS, Hunsicker LG (1995) Temporal changes of MR findings in central pontine myelinolysis. Am J Neuroradiol 16:975–977PubMed
12.
Zurück zum Zitat McGraw P, Edwards-Brown MK (1998) Reversal of MR findings of central pontine myelinolysis. J Comput Assist Tomogr 22:989–991CrossRefPubMed McGraw P, Edwards-Brown MK (1998) Reversal of MR findings of central pontine myelinolysis. J Comput Assist Tomogr 22:989–991CrossRefPubMed
13.
Zurück zum Zitat Niehaus L, Kulozik A, Lehmann R (2001) Reversible central pontine and extrapontine myelinolysis in a 16-year-old girl. Childs Nerv Syst 17:294–296PubMed Niehaus L, Kulozik A, Lehmann R (2001) Reversible central pontine and extrapontine myelinolysis in a 16-year-old girl. Childs Nerv Syst 17:294–296PubMed
14.
Zurück zum Zitat Chu K, Kang DW, Ko SB, Kim M (2001) Diffusion-weighted MR findings of central pontine and extrapontine myelinolysis. Acta Neurol Scand 104:385–388CrossRefPubMed Chu K, Kang DW, Ko SB, Kim M (2001) Diffusion-weighted MR findings of central pontine and extrapontine myelinolysis. Acta Neurol Scand 104:385–388CrossRefPubMed
15.
Zurück zum Zitat Laubenberger J, Schneider B, Ansorge O, Goetz F, Haussinger D, Volk B, Langer M (1996) Central pontine myelinolysis: clinical presentation and radiologic findings. Eur Radiol 6:177–183PubMed Laubenberger J, Schneider B, Ansorge O, Goetz F, Haussinger D, Volk B, Langer M (1996) Central pontine myelinolysis: clinical presentation and radiologic findings. Eur Radiol 6:177–183PubMed
16.
Zurück zum Zitat Menger H, Jorg J (1999) Outcome of central pontine and extrapontine myelinolysis (n=44). J Neurol 246:700–705PubMed Menger H, Jorg J (1999) Outcome of central pontine and extrapontine myelinolysis (n=44). J Neurol 246:700–705PubMed
17.
Zurück zum Zitat Norenberg MD (1983) A hypothesis of osmotic endothelial injury. A pathogenetic mechanism in central pontine myelinolysis. Arch Neurol 40:66–69PubMed Norenberg MD (1983) A hypothesis of osmotic endothelial injury. A pathogenetic mechanism in central pontine myelinolysis. Arch Neurol 40:66–69PubMed
18.
Zurück zum Zitat Lien YH, Shapiro JI, Chan L (1991) Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia. Implications for the pathogenesis of central pontine myelinolysis. J Clin Invest 88:303–309PubMed Lien YH, Shapiro JI, Chan L (1991) Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia. Implications for the pathogenesis of central pontine myelinolysis. J Clin Invest 88:303–309PubMed
Metadaten
Titel
Magnetic resonance imaging of sequelae of central pontine myelinolysis in chronic alcohol abusers
verfasst von
Akira Uchino
Takefumi Yuzuriha
Masaru Murakami
Koichi Endoh
Shigeto Hiejima
Hiroshi Koga
Sho Kudo
Publikationsdatum
01.12.2003
Verlag
Springer-Verlag
Erschienen in
Neuroradiology / Ausgabe 12/2003
Print ISSN: 0028-3940
Elektronische ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-003-1095-9

Weitere Artikel der Ausgabe 12/2003

Neuroradiology 12/2003 Zur Ausgabe

Acknowledgement to our Referees

Acknowledgement to Referees

Society News

December 2003

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.