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Erschienen in: Urolithiasis 3/2009

01.06.2009 | Original Paper

Effects of calcium supplementation on body weight reduction in overweight calcium stone formers

verfasst von: Viviane Barcellos Menon, Alessandra Calábria Baxmann, Leila Froeder, Lígia Araújo Martini, Ita Pfeferman Heilberg

Erschienen in: Urolithiasis | Ausgabe 3/2009

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Abstract

A randomized, placebo-controlled trial was conducted in overweight calcium stone-forming (CSF) patients, to evaluate the effect of calcium supplementation associated with a calorie-restricted diet on body weight (BW) and fat reduction and its potential changes upon serum and urinary parameters. Fifteen patients were placed on a hypocaloric diet for 3 months, supplemented with either calcium carbonate (CaCO3, n = 8) or placebo (n = 7), 500 mg bid. Blood and 24-h urine samples were collected and body composition was assessed at baseline and after the intervention. At the end of the study, final BW was significantly lower vs baseline in both CaCO3 (74 ± 14 vs. 80 ± 14 kg, P = 0.01) and placebo groups (80 ± 10 vs. 87 ± 9 kg, P = 0.02) but the mean percentage of loss of body weight and body fat did not differ between CaCO3 and placebo (7.0 ± 2.0 vs. 8.0 ± 3.0%, P = 0.40 and 13.0 ± 7.0 vs. 13.0 ± 10.0%; P = 0.81, respectively). After CaCO3 or placebo, no significant differences versus baseline were observed for urinary parameters in both CaCO3 and placebo, except for a higher mean urinary citrate in placebo group. These data suggest that increasing calcium intake by calcium carbonate supplementation did not contribute to a further reduction of BW and fat in overweight CSF patients submitted to a hypocaloric diet nor altered urinary lithogenic parameters.
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Metadaten
Titel
Effects of calcium supplementation on body weight reduction in overweight calcium stone formers
verfasst von
Viviane Barcellos Menon
Alessandra Calábria Baxmann
Leila Froeder
Lígia Araújo Martini
Ita Pfeferman Heilberg
Publikationsdatum
01.06.2009
Verlag
Springer-Verlag
Erschienen in
Urolithiasis / Ausgabe 3/2009
Print ISSN: 2194-7228
Elektronische ISSN: 2194-7236
DOI
https://doi.org/10.1007/s00240-009-0187-3

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