Skip to main content
Erschienen in: Pediatric Cardiology 5/2016

26.02.2016 | Original Article

Aiming to Preserve Pulmonary Valve Function in Tetralogy of Fallot Repair: Comparing a New Approach to Traditional Management

verfasst von: Danielle Gottlieb Sen, Marc Najjar, Betul Yimaz, Stéphanie M. Levasseur, Bindu Kalessan, Jan M. Quaegebeur, Emile A. Bacha

Erschienen in: Pediatric Cardiology | Ausgabe 5/2016

Einloggen, um Zugang zu erhalten

Abstract

Pulmonary valve (PV) incompetence following transannular patch (TAP) repair of tetralogy of Fallot (TOF) results in long-term morbidity and mortality. Valve-sparing repairs have recently gained recognition; however, they may be associated with residual pulmonary stenosis (PS) in patients with small PV z scores. We sought to determine whether a repair that increases the PV annulus and augments the valve leaflet with a biomaterial would result in annular growth and in longer duration of valve competence compared with TAP. Eighty patients (median age 136 days, range 4–350) who underwent surgical repair of TOF between 2010 and 2014 were included in the study. Patients were divided into three groups based on the PV intervention: balloon dilation/valvotomy (n = 29), valve-sparing transannular repair (VSTAR) (n = 19) and TAP (n = 32). Intraoperative, early postoperative and midterm follow-up echocardiographic data (median 19 months, range 1–59) were obtained. The primary outcomes were the presence and severity of pulmonary regurgitation and/or PS. Compared with TAP, VSTAR patients demonstrated significantly less severe PR with 100 % freedom of severe PR immediately post-op (vs. 0 % in TAP), 60 % at 6 months and 20 % at 20 months. There were no differences in PS between VSTAR and TAP at follow-up. A subgroup analysis of the VSTAR group was performed. PV z scores were calculated and fit to a random effects model. Patient data fit the model closely, predicting a reproducible increase in valve annulus size over time. With better short-term and comparable midterm results, VSTAR may be appropriate for TOF repair in patients with small PV that would conventionally require a TAP.
Literatur
1.
Zurück zum Zitat Anagnostopoulos P, Azakie A, Natarajan S et al (2007) Pulmonary valve cusp augmentation with autologous pericardium may improve early outcome for tetralogy of Fallot. J Thorac Cardiovasc Surg 133(3):640–647CrossRefPubMed Anagnostopoulos P, Azakie A, Natarajan S et al (2007) Pulmonary valve cusp augmentation with autologous pericardium may improve early outcome for tetralogy of Fallot. J Thorac Cardiovasc Surg 133(3):640–647CrossRefPubMed
2.
Zurück zum Zitat Attanawanich S, Ngodgnamthaweesuk M (2012) Pulmonary cusp augmentation in repair of tetralogy of Fallot. Asian Cardiovasc Thorac Ann 21(1):9–13CrossRef Attanawanich S, Ngodgnamthaweesuk M (2012) Pulmonary cusp augmentation in repair of tetralogy of Fallot. Asian Cardiovasc Thorac Ann 21(1):9–13CrossRef
4.
Zurück zum Zitat Bautista-Hernandez V, Cardenas I, Martinez-Bendayan I et al (2013) Valve-sparing tetralogy of Fallot repair with intraoperative dilation of the pulmonary valve. Pediatr Cardiol 34:918–923CrossRefPubMed Bautista-Hernandez V, Cardenas I, Martinez-Bendayan I et al (2013) Valve-sparing tetralogy of Fallot repair with intraoperative dilation of the pulmonary valve. Pediatr Cardiol 34:918–923CrossRefPubMed
5.
Zurück zum Zitat Brown JW, Ruzmetov M, Vijay P et al (2007) Right ventricular outflow tract reconstruction with a polytetrafluoroethylene monocusp valve: a twelve-year experience. J Thorac Cardiovasc Surg 133:1336–1343CrossRefPubMed Brown JW, Ruzmetov M, Vijay P et al (2007) Right ventricular outflow tract reconstruction with a polytetrafluoroethylene monocusp valve: a twelve-year experience. J Thorac Cardiovasc Surg 133:1336–1343CrossRefPubMed
6.
7.
Zurück zum Zitat Horton KD, Meece RW, Hill JC (2009) Assessment of the right ventricle by echocardiography: a primer for cardiac sonographers. J Am Soc Echocardiogr 22:776–792CrossRefPubMed Horton KD, Meece RW, Hill JC (2009) Assessment of the right ventricle by echocardiography: a primer for cardiac sonographers. J Am Soc Echocardiogr 22:776–792CrossRefPubMed
8.
Zurück zum Zitat Hua Z, Li S, Wang L et al (2011) A new pulmonary valve cusp plasty technique markedly decreases transannular patch rate and improves midterm outcomes of tetralogy of Fallot repair. Eur J Cardiothorac Surg 40:1221–1226PubMed Hua Z, Li S, Wang L et al (2011) A new pulmonary valve cusp plasty technique markedly decreases transannular patch rate and improves midterm outcomes of tetralogy of Fallot repair. Eur J Cardiothorac Surg 40:1221–1226PubMed
9.
Zurück zum Zitat Ito H, Ota N, Murata M et al (2013) Technical modification enabling pulmonary valve-sparing repair of a severely hypoplastic pulmonary annulus in patients with tetralogy of Fallot. Interact Cardiovasc Thorac Surg 16:802–807CrossRefPubMedPubMedCentral Ito H, Ota N, Murata M et al (2013) Technical modification enabling pulmonary valve-sparing repair of a severely hypoplastic pulmonary annulus in patients with tetralogy of Fallot. Interact Cardiovasc Thorac Surg 16:802–807CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Latus H, Gummel K, Rupp S et al (2013) Beneficial effects of residual right ventricular outflow tract obstruction on right ventricular volume and function in patients after repair of tetralogy of Fallot. Pediatr Cardiol 34(2):424–430CrossRefPubMed Latus H, Gummel K, Rupp S et al (2013) Beneficial effects of residual right ventricular outflow tract obstruction on right ventricular volume and function in patients after repair of tetralogy of Fallot. Pediatr Cardiol 34(2):424–430CrossRefPubMed
11.
Zurück zum Zitat Murphy JG, Gersh BJ, Mair DD et al (1993) Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot. N Engl J Med 329(9):593–599CrossRefPubMed Murphy JG, Gersh BJ, Mair DD et al (1993) Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot. N Engl J Med 329(9):593–599CrossRefPubMed
13.
Zurück zum Zitat Sasson L, Houri S, Raucher Sternfeld A et al (2013) Right ventricular outflow tract strategies for repair of tetralogy of Fallot: effect of monocusp valve reconstruction. Eur J Cardiothorac Surg 43(4):743–751. doi:10.1093/ejcts/ezs479 CrossRefPubMed Sasson L, Houri S, Raucher Sternfeld A et al (2013) Right ventricular outflow tract strategies for repair of tetralogy of Fallot: effect of monocusp valve reconstruction. Eur J Cardiothorac Surg 43(4):743–751. doi:10.​1093/​ejcts/​ezs479 CrossRefPubMed
14.
Zurück zum Zitat Stewart R, Backer C, Young L et al (2005) Tetralogy of Fallot: results of a pulmonary valve-sparing strategy. Ann Thorac Surg 80:1431–1439CrossRefPubMed Stewart R, Backer C, Young L et al (2005) Tetralogy of Fallot: results of a pulmonary valve-sparing strategy. Ann Thorac Surg 80:1431–1439CrossRefPubMed
15.
Zurück zum Zitat Sung S, Kim S, Woo JS et al (2003) Pulmonic valve annular enlargement with valve repair in tetralogy of Fallot. Ann Thorac Surg 75:303–305CrossRefPubMed Sung S, Kim S, Woo JS et al (2003) Pulmonic valve annular enlargement with valve repair in tetralogy of Fallot. Ann Thorac Surg 75:303–305CrossRefPubMed
16.
Zurück zum Zitat Valente AM, Gauvreau K, Assenza G et al (2014) Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of Fallot enrolled in the INDICATOR cohort. Heart 100(3):247–253CrossRefPubMed Valente AM, Gauvreau K, Assenza G et al (2014) Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of Fallot enrolled in the INDICATOR cohort. Heart 100(3):247–253CrossRefPubMed
Metadaten
Titel
Aiming to Preserve Pulmonary Valve Function in Tetralogy of Fallot Repair: Comparing a New Approach to Traditional Management
verfasst von
Danielle Gottlieb Sen
Marc Najjar
Betul Yimaz
Stéphanie M. Levasseur
Bindu Kalessan
Jan M. Quaegebeur
Emile A. Bacha
Publikationsdatum
26.02.2016
Verlag
Springer US
Erschienen in
Pediatric Cardiology / Ausgabe 5/2016
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-016-1355-1

Weitere Artikel der Ausgabe 5/2016

Pediatric Cardiology 5/2016 Zur Ausgabe

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.