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Erschienen in: Pediatric Radiology 11/2010

01.11.2010 | Case Report

Contralateral hemimicrencephaly in neonatal hemimegalencephaly

verfasst von: Mark S. Shiroishi, Hollie A. Jackson, Marvin D. Nelson Jr., Stefan Bluml, Ashok Panigrahy

Erschienen in: Pediatric Radiology | Ausgabe 11/2010

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Abstract

Identification of abnormalities in the contralateral hemisphere in patients with hemimegalencephaly is critical in their management. In this report, we present a 5-day-old neonate with hemimegalencephaly who demonstrated an enlarged ipsilateral cerebral hemisphere and diffuse volume loss in the contralateral hemisphere on conventional MR imaging sequences. The ipsilateral frontal white matter demonstrated relatively increased NAA, fractional anistropy, and cerebral blood volume values compared to published normative data. In addition, the white matter of the contralateral hemisphere demonstrated elevated lactate and increased mean diffusivity compared to published normative data, supporting the abnormal conventional MR findings. Advanced MR neuroimaging techniques may help further confirm and characterize abnormalities in the smaller contralateral hemisphere in neonatal hemimegalencephaly.
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Metadaten
Titel
Contralateral hemimicrencephaly in neonatal hemimegalencephaly
verfasst von
Mark S. Shiroishi
Hollie A. Jackson
Marvin D. Nelson Jr.
Stefan Bluml
Ashok Panigrahy
Publikationsdatum
01.11.2010
Verlag
Springer-Verlag
Erschienen in
Pediatric Radiology / Ausgabe 11/2010
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-010-1624-8

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