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Prenatal diagnosis of congenital lung malformations

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Abstract

Prenatal diagnosis of congenital lung anomalies has increased in recent years as imaging methods have benefitted from technical improvements. The purpose of this pictorial essay is to illustrate typical imaging findings of a wide spectrum of congenital lung anomalies on prenatal US and MRI. Moreover, we propose an algorithm based on imaging findings to facilitate the differential diagnosis, and suggest a follow-up algorithm during pregnancy and in the immediate postnatal period.

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References

  1. Berrocal T, Madrid C, Novo S et al (2004) Congenital anomalies of the tracheobronchial tree, lung and mediastinum: embryology, radiology and pathology. Radiographics 24:e17

    Article  PubMed  Google Scholar 

  2. Eber E (2007) Antenatal diagnosis of congenital thoracic malformations: early surgery, late surgery or no surgery. Semi Resp Crit Care Med 28:355–366

    Article  Google Scholar 

  3. Vu L, Tsao TJ, Lee H et al (2007) Characteristics of congenital cystic adenomatois malformation associated with noninmune hydrops and outcome. J Pediatr Surg 42:1351–1356

    Article  PubMed  Google Scholar 

  4. Azizkhan RG, Crombleholme TM (2008) Congenital cystic lung disease: contemporary antenatal and postnatal management. Pediatr Surg Int 24:643–657

    Article  PubMed  Google Scholar 

  5. Curran PF, Jelin EB, Rand L et al (2010) Prenatal steroids for microcystic congenital cystic adenomatoid malformation. J Pediatr Surg 45:145–150

    Article  PubMed  Google Scholar 

  6. Stocker JT, Madewell JE, Drake RM (1977) Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum. Hum Pathol 8:155–171

    Article  PubMed  CAS  Google Scholar 

  7. Rosado-de-christenson ML, Stocker JT (1991) Congenital cystic adenomatoid malformation. Radiographics 11:865–886

    PubMed  CAS  Google Scholar 

  8. Stocker JT (2009) Cystic lung disease in infants and children. Fetal Pediatr Pathol 28:155–184

    Article  PubMed  Google Scholar 

  9. Langston C (2003) New concepts in the pathology of congenital lung malformation. Semin Pediatr Surg 12:17–37

    Article  PubMed  Google Scholar 

  10. Büsing KAK, Schaible T, Neff KW (2006) Fetal MRI. Diagnostic in cases of congenital cystadenomatoid malformation of the lung. Radiologe 46:133–138

    Article  PubMed  Google Scholar 

  11. Williams HJ, Johnson KJ (2002) Imaging of congenital cystic lung lesions. Pediatr Resp Rev 3:120–127

    Article  CAS  Google Scholar 

  12. Cannie M, Jani J, de Keyzer F et al (2008) Magnetic resonance imaging of the fetal lung: a pictorial essay. Eur Radiol 18:1364–1374

    Article  PubMed  CAS  Google Scholar 

  13. Daltro P, Werner H, Gasparetto TD et al (2010) Congenital chest malformations: a multimodality approach with emphasis on fetal MR Imaging. Radiographics 30:385–395

    Article  PubMed  Google Scholar 

  14. Crombleholme TM, Coleman B, Hedrick H et al (2002) Cystic adenomatoid malformation volume ratio predicts outcome in prenatally diagnosed cystic adenomatoid malformation of the lung. J Pediatr Surg 37:331–338

    Article  PubMed  Google Scholar 

  15. Epelman M, Kreiger PA, Servaes S et al (2010) Current imaging of prenatally diagnosed congenital lung lesions. Semin Ultrasound CT MRI 31:141–157

    Article  Google Scholar 

  16. Langston C (2003) Intralobar sequestration revisisted. Pediatr Dev Pathol 6:283

    Article  PubMed  Google Scholar 

  17. Biyyam DR, Chapman T, Ferguson MR et al (2010) Congenital lung abnormalities: Embryologic features, prenatal diagnosis and postnatal radiologic-pathologic correlation. Radiographics 30:1721–1738

    Article  PubMed  Google Scholar 

  18. Kunisaki SM, Fauza DO, Nemes LP et al (2006) Bronchial atresia: the hidden pathology within a spectrum of prenatally diagnosed lung masses. J Pediatr Surg 41:61–65

    Article  PubMed  Google Scholar 

  19. Yu-Peng L, Chih-Ping C, Shin-Lin S et al (2010) Fetal cystic lung lesions: evaluation with magnetic resonance imaging. Pediatr Pulmonol 45:592–600

    Google Scholar 

  20. Riedlinger WF, Vargas SO, Jennings RW et al (2006) Bronchial atresia is common to extralobar sequestration, intralobar sequestration, congenital cystic adenomatoid malformation and lobar emphysema. Pediatr Dev Pathol 9:361–373

    Article  PubMed  Google Scholar 

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Correspondence to Leonor Alamo.

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Alamo, L., Gudinchet, F., Reinberg, O. et al. Prenatal diagnosis of congenital lung malformations. Pediatr Radiol 42, 273–283 (2012). https://doi.org/10.1007/s00247-011-2303-0

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  • DOI: https://doi.org/10.1007/s00247-011-2303-0

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