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Skeletal Radiology

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01.02.2007 | Review Article

Langerhans cell histiocytosis

verfasst von: Kevin Bradford Hoover, Daniel I. Rosenthal, Henry Mankin

Erschienen in: Skeletal Radiology | Ausgabe 2/2007

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Abstract

Langerhans cell histiocytosis (LCH) is a complex disease entity comprised of three distinct clinical syndromes that demonstrate indistinguishable histology. These syndromes are: eosinophilic granuloma, which is predominantly osseous or pulmonary; Hand-Schûller-Christian’s disease, which involves multiple organ systems and, most typically, the skull base; and Letterer-Siwe’s disease, the most severe disease manifestation, which typically involves the abdominal viscera. This article reviews our current understanding of Langerhans cell histiocytosis by discussing the history, histology, etiology, and treatment of the disease. It focuses on the radiographic findings and imaging modalities that are the most useful in disease diagnosis and management.

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Titel: Langerhans cell histiocytosis
verfasst von: Kevin Bradford Hoover
Daniel I. Rosenthal
Henry Mankin
Publikationsdatum: 01.02.2007
Verlag: Springer-Verlag
Erschienen in: Skeletal Radiology / Ausgabe 2/2007
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-006-0193-2

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