Skip to main content
Erschienen in: Skeletal Radiology 6/2007

01.06.2007 | Case Report

Solitary intramuscular myxoma with monostotic fibrous dysplasia as a rare variant of Mazabraud’s syndrome

verfasst von: Makoto Endo, Akira Kawai, Eisuke Kobayashi, Yuki Morimoto, Umio Yamaguchi, Fumihiko Nakatani, Hirokazu Chuman, Kunihiko Seki, Yasuo Beppu

Erschienen in: Skeletal Radiology | Ausgabe 6/2007

Einloggen, um Zugang zu erhalten

Abstract

The rare coexistence of intramuscular myxoma (IM) and fibrous dysplasia (FD) is known as Mazabraud’s syndrome. IM tends to occur multifocally and is associated most frequently with polyostotic FD in Mazabraud’s syndrome. We present an extremely rare combination of a solitary IM and monostotic FD as a variant of Mazabraud’s syndrome, and discuss the importance of recognizing this rare coexistence for appropriate management of the patient.
Literatur
1.
Zurück zum Zitat Henschen F. Fall von ostitis Fibrosa mit multiplen Tumoren in der umgebenden Muskulatur. Verh Dtsch Ges Pathol 1926;21:93–7. Henschen F. Fall von ostitis Fibrosa mit multiplen Tumoren in der umgebenden Muskulatur. Verh Dtsch Ges Pathol 1926;21:93–7.
2.
Zurück zum Zitat Mazabraud A, Semat P, Roze R. A propos de I’association de fibromyxomes des tissus molle a la dysplasie fibreuse des os. Presse Med 1967;75:2223–8.PubMed Mazabraud A, Semat P, Roze R. A propos de I’association de fibromyxomes des tissus molle a la dysplasie fibreuse des os. Presse Med 1967;75:2223–8.PubMed
3.
Zurück zum Zitat Wirth WA, Leavitt D, Enzinger FM. Multiple intramuscular myxomas. Another extraskeletal manifestation of fibrous dysplasia. Cancer 1971;27:1167–73.CrossRef Wirth WA, Leavitt D, Enzinger FM. Multiple intramuscular myxomas. Another extraskeletal manifestation of fibrous dysplasia. Cancer 1971;27:1167–73.CrossRef
4.
Zurück zum Zitat Segev Z, Reiner S. Intramuscular myxoma associated with fibrous dysplasia of adjacent bone. Harefuah 1985;108:493–4.PubMed Segev Z, Reiner S. Intramuscular myxoma associated with fibrous dysplasia of adjacent bone. Harefuah 1985;108:493–4.PubMed
5.
Zurück zum Zitat Sundaram M, McDonald DJ, Merenda G. Intramuscular myxoma: a rare but important association with fibrous dysplasia of bone. Am J Roentgenol 1989;153:107–8.CrossRef Sundaram M, McDonald DJ, Merenda G. Intramuscular myxoma: a rare but important association with fibrous dysplasia of bone. Am J Roentgenol 1989;153:107–8.CrossRef
6.
Zurück zum Zitat Gober GA, Nicholas RW. Case report 800: skeletal fibrous dysplasia associated with intramuscular myxoma (Mazabraud’s syndrome). Skelet Radiol 1993;22:452–5.CrossRef Gober GA, Nicholas RW. Case report 800: skeletal fibrous dysplasia associated with intramuscular myxoma (Mazabraud’s syndrome). Skelet Radiol 1993;22:452–5.CrossRef
7.
Zurück zum Zitat Prayson MA, Leeson MC. Soft-tissue myxomas and fibrous dysplasia of bone. A case report and review of the literature. Clin Orthop Relat Res 1993;222–8. Prayson MA, Leeson MC. Soft-tissue myxomas and fibrous dysplasia of bone. A case report and review of the literature. Clin Orthop Relat Res 1993;222–8.
8.
Zurück zum Zitat Aoki T, Kouho H, Hisaoka M, Hashimoto H, Nakata H, Sakai A. Intramuscular myxoma with fibrous dysplasia: a report of two cases with a review of the literature. Pathol Int 1995;45:165–71.CrossRef Aoki T, Kouho H, Hisaoka M, Hashimoto H, Nakata H, Sakai A. Intramuscular myxoma with fibrous dysplasia: a report of two cases with a review of the literature. Pathol Int 1995;45:165–71.CrossRef
9.
Zurück zum Zitat Fujii K, Inoue M, Araki Y, Ishida O. Multiple intramuscular myxomas associated with polyostotic fibrous dysplasia. Eur J Radiol 1996;22:152–4.CrossRef Fujii K, Inoue M, Araki Y, Ishida O. Multiple intramuscular myxomas associated with polyostotic fibrous dysplasia. Eur J Radiol 1996;22:152–4.CrossRef
10.
Zurück zum Zitat Court-Payen M, Ingemann Jensen L, Bjerregaard B, Schwarz Lausten G, Skjoldbye B. Intramuscular myxoma and fibrous dysplasia of bone-Mazabraud’s syndrome. A case report. Acta Radiol 1997;38:368–71.PubMed Court-Payen M, Ingemann Jensen L, Bjerregaard B, Schwarz Lausten G, Skjoldbye B. Intramuscular myxoma and fibrous dysplasia of bone-Mazabraud’s syndrome. A case report. Acta Radiol 1997;38:368–71.PubMed
11.
Zurück zum Zitat Szendroi M, Rahoty P, Antal I, Kiss J. Fibrous dysplasia associated with intramuscular myxoma (Mazabraud’s syndrome): a long-term follow-up of three cases. J Cancer Res Clin Oncol 1998;124:401–6.CrossRef Szendroi M, Rahoty P, Antal I, Kiss J. Fibrous dysplasia associated with intramuscular myxoma (Mazabraud’s syndrome): a long-term follow-up of three cases. J Cancer Res Clin Oncol 1998;124:401–6.CrossRef
12.
Zurück zum Zitat Cabral CE, Guedes P, Fonseca T, Rezende JF, Cruz LC Jr, Smith J. Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud’s syndrome. Skelet Radiol 1998;27:278–82.CrossRef Cabral CE, Guedes P, Fonseca T, Rezende JF, Cruz LC Jr, Smith J. Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud’s syndrome. Skelet Radiol 1998;27:278–82.CrossRef
13.
Zurück zum Zitat Walker RE, Schwartz RK, Gale DR. Musculoskeletal case of the day. Mazabraud’s syndrome (intramuscular myxomas associated with fibrous dysplasia of bone). Am J Roentgenol 1999;173:797, 800–2.CrossRef Walker RE, Schwartz RK, Gale DR. Musculoskeletal case of the day. Mazabraud’s syndrome (intramuscular myxomas associated with fibrous dysplasia of bone). Am J Roentgenol 1999;173:797, 800–2.CrossRef
14.
Zurück zum Zitat Lopez-Ben R, Pitt MJ, Jaffe KA, Siegal GP. Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud’s syndrome. Skelet Radiol 1999;28:522–6.CrossRef Lopez-Ben R, Pitt MJ, Jaffe KA, Siegal GP. Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud’s syndrome. Skelet Radiol 1999;28:522–6.CrossRef
15.
Zurück zum Zitat Okamoto S, Hisaoka M, Ushijima M, Nakahara S, Toyoshima S, Hashimoto H. Activating Gs(alpha) mutation in intramuscular myxomas with and without fibrous dysplasia of bone. Virchows Arch 2000;437:133–7.CrossRef Okamoto S, Hisaoka M, Ushijima M, Nakahara S, Toyoshima S, Hashimoto H. Activating Gs(alpha) mutation in intramuscular myxomas with and without fibrous dysplasia of bone. Virchows Arch 2000;437:133–7.CrossRef
16.
Zurück zum Zitat Faivre L, Nivelon-Chevallier A, Kottler ML, Robinet C, Khau Van Kien P, Lorcerie B, Munnich A, Maroteaux P, Cormier-Daire V, LeMerrer M. Mazabraud syndrome in two patients: clinical overlap with McCune-Albright syndrome. Am J Med Genet 2001;99:132–6.CrossRef Faivre L, Nivelon-Chevallier A, Kottler ML, Robinet C, Khau Van Kien P, Lorcerie B, Munnich A, Maroteaux P, Cormier-Daire V, LeMerrer M. Mazabraud syndrome in two patients: clinical overlap with McCune-Albright syndrome. Am J Med Genet 2001;99:132–6.CrossRef
17.
Zurück zum Zitat Iwasko N, Steinbach LS, Disler D, Pathria M, Hottya GA, Kattapuram S, et al. Imaging findings in Mazabraud’s syndrome: seven new cases. Skelet Radiol 2002;31:81–7.CrossRef Iwasko N, Steinbach LS, Disler D, Pathria M, Hottya GA, Kattapuram S, et al. Imaging findings in Mazabraud’s syndrome: seven new cases. Skelet Radiol 2002;31:81–7.CrossRef
18.
Zurück zum Zitat Nguyen BD, Ram PC. Mazabraud’s syndrome with sarcomatous transformation: scintigraphic and radiologic imaging. Clin Nucl Med 2005;30:829–30.CrossRef Nguyen BD, Ram PC. Mazabraud’s syndrome with sarcomatous transformation: scintigraphic and radiologic imaging. Clin Nucl Med 2005;30:829–30.CrossRef
19.
Zurück zum Zitat Silver WP, Harrelson JM, Scully SP. Intramuscular myxoma: a clinicopathologic study of 17 patients. Clin Orthop Relat Res 2002;191–7.CrossRef Silver WP, Harrelson JM, Scully SP. Intramuscular myxoma: a clinicopathologic study of 17 patients. Clin Orthop Relat Res 2002;191–7.CrossRef
20.
Zurück zum Zitat Nielsen G, Stenman G. Intramuscular myxoma. In: Fletcher CDM, Unni KK, Mertens F (eds) World Health Organization classification of tumours pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002. p. 186–7. Nielsen G, Stenman G. Intramuscular myxoma. In: Fletcher CDM, Unni KK, Mertens F (eds) World Health Organization classification of tumours pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002. p. 186–7.
21.
Zurück zum Zitat Siegal G, Cin PD, Araujo ES. Fibrous dysplasia. In: Fletcher CDM, Unni KK, Mertens F (eds) World Health Organization classification of tumours pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002. p. 341–2. Siegal G, Cin PD, Araujo ES. Fibrous dysplasia. In: Fletcher CDM, Unni KK, Mertens F (eds) World Health Organization classification of tumours pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002. p. 341–2.
22.
Zurück zum Zitat Harris WH, Dudley HR, Barry RJ. The natural history of fibrous dysplasia. J Bone Jt Surg Am 1962;44:207–33.CrossRef Harris WH, Dudley HR, Barry RJ. The natural history of fibrous dysplasia. J Bone Jt Surg Am 1962;44:207–33.CrossRef
23.
Zurück zum Zitat Cohen MM Jr. Fibrous dysplasia is a neoplasm. Am J Med Genet 2001;98:290–3.CrossRef Cohen MM Jr. Fibrous dysplasia is a neoplasm. Am J Med Genet 2001;98:290–3.CrossRef
24.
Zurück zum Zitat Dal Cin P, Sciot R, Brys P, de Wever I, Dorfman H, Fletchera CD, et al. Recurrent chromosome aberrations in fibrous dysplasia of the bone: a report of the CHAMP study group. CHromosomes And MorPhology. Cancer Genet Cytogenet 2000;122:30–2.CrossRef Dal Cin P, Sciot R, Brys P, de Wever I, Dorfman H, Fletchera CD, et al. Recurrent chromosome aberrations in fibrous dysplasia of the bone: a report of the CHAMP study group. CHromosomes And MorPhology. Cancer Genet Cytogenet 2000;122:30–2.CrossRef
25.
Zurück zum Zitat Bancroft LW, Kransdorf MJ, Menke DM, O’Connor MI, Foster WC. Intramuscular myxoma: characteristic MR imaging features. Am J Roentgenol 2002;178:1255–9.CrossRef Bancroft LW, Kransdorf MJ, Menke DM, O’Connor MI, Foster WC. Intramuscular myxoma: characteristic MR imaging features. Am J Roentgenol 2002;178:1255–9.CrossRef
26.
Zurück zum Zitat Jhala DN, Eltoum I, Carroll AJ, Lopez-Ben R, Lopez-Terrada D, Rao PH, et al. Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud’s syndrome: a case report emphasizing the cytological and cytogenetic findings. Hum Pathol 2003;34:1354–7.CrossRef Jhala DN, Eltoum I, Carroll AJ, Lopez-Ben R, Lopez-Terrada D, Rao PH, et al. Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud’s syndrome: a case report emphasizing the cytological and cytogenetic findings. Hum Pathol 2003;34:1354–7.CrossRef
Metadaten
Titel
Solitary intramuscular myxoma with monostotic fibrous dysplasia as a rare variant of Mazabraud’s syndrome
verfasst von
Makoto Endo
Akira Kawai
Eisuke Kobayashi
Yuki Morimoto
Umio Yamaguchi
Fumihiko Nakatani
Hirokazu Chuman
Kunihiko Seki
Yasuo Beppu
Publikationsdatum
01.06.2007
Verlag
Springer Berlin Heidelberg
Erschienen in
Skeletal Radiology / Ausgabe 6/2007
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-006-0234-x

Weitere Artikel der Ausgabe 6/2007

Skeletal Radiology 6/2007 Zur Ausgabe

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.