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Erschienen in: Abdominal Radiology 5/2005

01.10.2005

Conventional enteroclysis with complementary MR enteroclysis: a combination of small bowel imaging

verfasst von: U. Korman, S. Kurugoglu, G. Ogut

Erschienen in: Abdominal Radiology | Ausgabe 5/2005

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Excerpt

In recent years, there have been important improvements in different technologies and procedures to evaluate small bowel diseases. Among these new technologies and procedures: push enteroscopy, capsule endoscopy, magnetic resonance enteroclysis (MRE), and computed tomographic enteroclysis (CTE) have provided competitive and/or complementary modalities compared with classic conventional small bowel through and conventional enteroclysis (CE) examinations [110]. As very well appreciated, all modalities have their own advantages and disadvantages and indications and limitations. Despite these technologic advances, radiologic workup remains the first stage in the diagnosis of small bowel diseases and CE is the gold standard in the evaluation of mucosal pathologies, morphologic changes, and luminal and functional abnormalities [11]. However, in some cases, the effectiveness of CE decreases due to overlapping bowel loops. In addition, pathologic changes may not be limited to the small bowel wall. Although CE provides indirect findings concerning the wall and perienteric structures, complementary imaging is often needed in cases in which the pathologic changes go beyond the small bowel wall. Cross-sectional imaging methods such as computed tomography (CT) and magnetic resonance imaginig (MRI) are not affected by overlapping bowel loops, provide sufficient information about mural pathologies, and determine the extraluminal extension of the disease and surrounding structures. Multidetector-row CT (MDCT) and MRI have become successful alternative cross-sectional imaging modalities for more detailed small bowel examinations [1218]. MRI has multiplanar imaging capacity and excellent soft tissue contrast without any radiation exposure. In addition, with improved breath-hold, fast and ultrafast imaging sequences, high performance gradient coils, and dedicated abdominal phased array coils, image quality of gastrointestinal MRI has improved and the timing handicap has been overcome [1522]. MDCT shares the same advantages as MRI but radiation poses well-known risks [10, 1214, 18]. This report discusses the technique and findings of the combination of CE and MRE in the evaluation of different small bowel diseases. …
Literatur
2.
Zurück zum Zitat Taylor AC, Buttigieg RJ, McDonald IG, Desmond PV. Prospective assessment of the diagnostic and therapeutic impact of small bowel pushes enteroscopy. Endoscopy 2003;35:951–956CrossRefPubMed Taylor AC, Buttigieg RJ, McDonald IG, Desmond PV. Prospective assessment of the diagnostic and therapeutic impact of small bowel pushes enteroscopy. Endoscopy 2003;35:951–956CrossRefPubMed
3.
Zurück zum Zitat Adler DG, Knipschield M, Gostout C. A prospective comparison of capsule endoscopy and push enteroscopy in patients with GI bleeding of obscure origin. Gastrointest Endosc 2004;59:492–498CrossRefPubMed Adler DG, Knipschield M, Gostout C. A prospective comparison of capsule endoscopy and push enteroscopy in patients with GI bleeding of obscure origin. Gastrointest Endosc 2004;59:492–498CrossRefPubMed
4.
Zurück zum Zitat Schreyer AG, Golder S, Seitz J, Herfarth H. New diagnostic avenues in inflammatory bowel diseases. Capsule endoscopy, magnetic resonance imaging and virtual enteroscopy. Dig Dis 2003;21:129–137CrossRefPubMed Schreyer AG, Golder S, Seitz J, Herfarth H. New diagnostic avenues in inflammatory bowel diseases. Capsule endoscopy, magnetic resonance imaging and virtual enteroscopy. Dig Dis 2003;21:129–137CrossRefPubMed
5.
Zurück zum Zitat Delvaux M, Fassler I, Gay G. Clinical usefulness of the endoscopic video capsule as the initial intestinal investigation in patients with obscure digestive bleeding: validation of a diagnostic strategy based on the patient outcome after 12 months. Endoscopy 2004;36:1067–1073CrossRefPubMed Delvaux M, Fassler I, Gay G. Clinical usefulness of the endoscopic video capsule as the initial intestinal investigation in patients with obscure digestive bleeding: validation of a diagnostic strategy based on the patient outcome after 12 months. Endoscopy 2004;36:1067–1073CrossRefPubMed
6.
Zurück zum Zitat Maieron A, Hubner D, Blaha B, et al. Multicenter retrospective evaluation of capsule endoscopy in clinical routine. Endoscopy 2004;36:864–868CrossRefPubMed Maieron A, Hubner D, Blaha B, et al. Multicenter retrospective evaluation of capsule endoscopy in clinical routine. Endoscopy 2004;36:864–868CrossRefPubMed
7.
Zurück zum Zitat Kovacs TO, Jensen DM. Recent advances in the endoscopic diagnosis and therapy of upper gastrointestinal, small intestinal and colonic bleeding. Med Clin North Am 2002;86:1319–1356CrossRefPubMed Kovacs TO, Jensen DM. Recent advances in the endoscopic diagnosis and therapy of upper gastrointestinal, small intestinal and colonic bleeding. Med Clin North Am 2002;86:1319–1356CrossRefPubMed
8.
Zurück zum Zitat Brizi MG, Minordi LM, Mirk P, et al. The state of the art of small bowel imaging: combine the old with the new. Rays 2002;27:51–65PubMed Brizi MG, Minordi LM, Mirk P, et al. The state of the art of small bowel imaging: combine the old with the new. Rays 2002;27:51–65PubMed
9.
Zurück zum Zitat Liangpunsakul S, Chadalawada V, Rex DK, et al. Wireless capsule endoscopy detects small bowel ulcers in patients with normal results from state of the art enteroclysis. Am J Gastroenterol 2003;98:1295–1298CrossRefPubMed Liangpunsakul S, Chadalawada V, Rex DK, et al. Wireless capsule endoscopy detects small bowel ulcers in patients with normal results from state of the art enteroclysis. Am J Gastroenterol 2003;98:1295–1298CrossRefPubMed
10.
Zurück zum Zitat Hara AK, Leighton JA, Sharma VK, Fleishner DE. Small bowel: preliminary comparison of capsule endoscopy with barium study and CT. Radiology 2004;230:260–265PubMed Hara AK, Leighton JA, Sharma VK, Fleishner DE. Small bowel: preliminary comparison of capsule endoscopy with barium study and CT. Radiology 2004;230:260–265PubMed
11.
Zurück zum Zitat Herlinger H, Maglinte DT, Yao T. Enteroclysis. Technique and variations. In: Herlinger H, Maglinte DT, Birnbaum BA (eds). Clinical imaging of the small intestine. New York: Springer-Verlag; 1999:95–123 Herlinger H, Maglinte DT, Yao T. Enteroclysis. Technique and variations. In: Herlinger H, Maglinte DT, Birnbaum BA (eds). Clinical imaging of the small intestine. New York: Springer-Verlag; 1999:95–123
12.
Zurück zum Zitat Horton KM, Fishman EK. The current status of multidetector row CT and three-dimensional imaging of the small bowel. Radiol Clin North Am 2003;41:199–212CrossRefPubMed Horton KM, Fishman EK. The current status of multidetector row CT and three-dimensional imaging of the small bowel. Radiol Clin North Am 2003;41:199–212CrossRefPubMed
13.
Zurück zum Zitat Maglinte DD, Bender GN, Heitkamp DE, et al. Multidetector-row helical CT enteroclysis. Radiol Clin North Am 2003;41:249–262CrossRefPubMed Maglinte DD, Bender GN, Heitkamp DE, et al. Multidetector-row helical CT enteroclysis. Radiol Clin North Am 2003;41:249–262CrossRefPubMed
14.
Zurück zum Zitat Boudiaf M, Jaff A, Soyer P, et al. Small-bowel diseases: prospective evaluation of multi-detector row helical CT enteroclysis in 107 consecutive patients. Radiology 2004;233:338–344PubMed Boudiaf M, Jaff A, Soyer P, et al. Small-bowel diseases: prospective evaluation of multi-detector row helical CT enteroclysis in 107 consecutive patients. Radiology 2004;233:338–344PubMed
15.
Zurück zum Zitat Umschaden HW, Szolar D, Gasser J, et al. Small-bowel disease: comparison of MR enteroclysis images with conventional enteroclysis and surgical findings. Radiology 2000;215:717–725PubMed Umschaden HW, Szolar D, Gasser J, et al. Small-bowel disease: comparison of MR enteroclysis images with conventional enteroclysis and surgical findings. Radiology 2000;215:717–725PubMed
16.
Zurück zum Zitat Maglinte DT, Siegelman ES, Kelvin FM. MR enteroclysis: the future of small-bowel imaging? Radiology 2000;215:639–641PubMed Maglinte DT, Siegelman ES, Kelvin FM. MR enteroclysis: the future of small-bowel imaging? Radiology 2000;215:639–641PubMed
18.
Zurück zum Zitat Schmidt S, Lepori D, Meuwly JY, et al. Prospective comparison of MR enteroclysis with multidetector spiral-CT enteroclysis: interobserver agreement and sensitivity by means of “sign-by-sign” correlation. Eur Radiol 2003;13:1303–1311PubMed Schmidt S, Lepori D, Meuwly JY, et al. Prospective comparison of MR enteroclysis with multidetector spiral-CT enteroclysis: interobserver agreement and sensitivity by means of “sign-by-sign” correlation. Eur Radiol 2003;13:1303–1311PubMed
19.
Zurück zum Zitat Marcos HB, Semelka RC. Evaluation of Crohn’s disease using half-Fourier RARE and gadolinium-enhanced SGE sequences: initial results. Magn Reson Imaging 2000;18:263–268CrossRefPubMed Marcos HB, Semelka RC. Evaluation of Crohn’s disease using half-Fourier RARE and gadolinium-enhanced SGE sequences: initial results. Magn Reson Imaging 2000;18:263–268CrossRefPubMed
20.
Zurück zum Zitat Ernst O, Asselah T, Caplan X, et al. Breath-hold fast spin echo MR imaging of Crohn’s disease. AJR 1998;170:127–128PubMed Ernst O, Asselah T, Caplan X, et al. Breath-hold fast spin echo MR imaging of Crohn’s disease. AJR 1998;170:127–128PubMed
21.
Zurück zum Zitat Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, et al. MR enteroclysis protocol comparison between 3D FLASH with fat saturation after intravenous gadolinium injection and true FISP sequences. Eur Radiol 2001;11:908–911CrossRefPubMed Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, et al. MR enteroclysis protocol comparison between 3D FLASH with fat saturation after intravenous gadolinium injection and true FISP sequences. Eur Radiol 2001;11:908–911CrossRefPubMed
22.
Zurück zum Zitat Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, Prassopoulos P. MR enteroclysis: technical considerations and clinical applications. Eur Radiol 2002;12:2651–2658PubMed Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, Prassopoulos P. MR enteroclysis: technical considerations and clinical applications. Eur Radiol 2002;12:2651–2658PubMed
23.
Zurück zum Zitat Herlinger HA. A modified technique for the double contrast small bowel enema. Gastrointest Radiol 1978;3:200–207CrossRef Herlinger HA. A modified technique for the double contrast small bowel enema. Gastrointest Radiol 1978;3:200–207CrossRef
24.
Zurück zum Zitat Herlinger HA. Small bowel (section VII). In: Gore RM, Levine MS, eds. Textbook of gastrointestinal radiology. Philadelphia: WB Saunders, 1994:704–890 Herlinger HA. Small bowel (section VII). In: Gore RM, Levine MS, eds. Textbook of gastrointestinal radiology. Philadelphia: WB Saunders, 1994:704–890
25.
Zurück zum Zitat Gourtsoyiannis NC (ed). Radiological imaging of the small intestine. Heidelberg: Springer-Verlag, 2002 Gourtsoyiannis NC (ed). Radiological imaging of the small intestine. Heidelberg: Springer-Verlag, 2002
26.
Zurück zum Zitat Herlinger HA, Maglinte D (eds). Clinical radiology of the small intestine. Philadelphia: WB Saunders, 1989 Herlinger HA, Maglinte D (eds). Clinical radiology of the small intestine. Philadelphia: WB Saunders, 1989
27.
Zurück zum Zitat Sands BE. From symptom to diagnosis: clinical distinctions among various forms of intestinal inflammation. Gastroenterology 2004;126:1518–32CrossRefPubMed Sands BE. From symptom to diagnosis: clinical distinctions among various forms of intestinal inflammation. Gastroenterology 2004;126:1518–32CrossRefPubMed
28.
Zurück zum Zitat Lomas DJ, Graves MJ. Small bowel MRI using water as a contrast medium. Br J Radiol 1999;72:994–997PubMed Lomas DJ, Graves MJ. Small bowel MRI using water as a contrast medium. Br J Radiol 1999;72:994–997PubMed
29.
Zurück zum Zitat Schreyer AG, Geissler A, Albrich H, et al. Abdominal MRI after enteroclysis or with oral contrast in patients with suspected or proven Crohn’s disease. Clin Gastroenterol Hepatol 2004;2:491–497CrossRefPubMed Schreyer AG, Geissler A, Albrich H, et al. Abdominal MRI after enteroclysis or with oral contrast in patients with suspected or proven Crohn’s disease. Clin Gastroenterol Hepatol 2004;2:491–497CrossRefPubMed
30.
Zurück zum Zitat Maccioni F, Viscido A, Marini M, Caprilli R. MRI evaluation of Crohn’s disease of the small and large bowel with the use of negative superparamagnetic oral contrast agents. Abdom Imaging 2002;27:384–393CrossRefPubMed Maccioni F, Viscido A, Marini M, Caprilli R. MRI evaluation of Crohn’s disease of the small and large bowel with the use of negative superparamagnetic oral contrast agents. Abdom Imaging 2002;27:384–393CrossRefPubMed
31.
Zurück zum Zitat Rieber A, Aschoff A, Nussle K, et al. MRI in the diagnosis of small bowel disease: use of positive and negative oral contrast media in combination with enteroclysis. Eur Radiol 2000;10:1377–1382CrossRefPubMed Rieber A, Aschoff A, Nussle K, et al. MRI in the diagnosis of small bowel disease: use of positive and negative oral contrast media in combination with enteroclysis. Eur Radiol 2000;10:1377–1382CrossRefPubMed
32.
Zurück zum Zitat Rieber A, Nussle K, Reinshagen M, et al. MRI of the abdomen with positive oral contrast agents for the diagnosis of inflammatory small bowel disease. Abdom Imaging 2002;27:394–399CrossRefPubMed Rieber A, Nussle K, Reinshagen M, et al. MRI of the abdomen with positive oral contrast agents for the diagnosis of inflammatory small bowel disease. Abdom Imaging 2002;27:394–399CrossRefPubMed
33.
Zurück zum Zitat Boraschi P, Braccini G, Gigoni R, et al. MR Enteroclysis using iron oxide particles (ferristene) as an endoluminal contrast agent: an open phase III trial. Magn Reson Imaging 2004;22:1085–1095CrossRefPubMed Boraschi P, Braccini G, Gigoni R, et al. MR Enteroclysis using iron oxide particles (ferristene) as an endoluminal contrast agent: an open phase III trial. Magn Reson Imaging 2004;22:1085–1095CrossRefPubMed
34.
Zurück zum Zitat Engelholm L, DeToeuf J, Herlinger H, Maglinte DD. Crohn’s disease of the small bowel. In: Herlinger H, Maglinte DD (eds). Clinical radiology of the small intestine. Philadelphia: WB Saunders, 1989:295–234 Engelholm L, DeToeuf J, Herlinger H, Maglinte DD. Crohn’s disease of the small bowel. In: Herlinger H, Maglinte DD (eds). Clinical radiology of the small intestine. Philadelphia: WB Saunders, 1989:295–234
35.
Zurück zum Zitat Prassopoulos P, Papanikolaou N, Grammatikakis J, et al. MR enteroclysis imaging of Crohn disease. Radiographics 2001;21:161–172PubMed Prassopoulos P, Papanikolaou N, Grammatikakis J, et al. MR enteroclysis imaging of Crohn disease. Radiographics 2001;21:161–172PubMed
36.
Zurück zum Zitat Masselli G, Brizi GM, Parrella A, et al. Crohn disease: magnetic resonance enteroclysis. Abdom Imaging 2004;29:326–334CrossRefPubMed Masselli G, Brizi GM, Parrella A, et al. Crohn disease: magnetic resonance enteroclysis. Abdom Imaging 2004;29:326–334CrossRefPubMed
37.
Zurück zum Zitat Koh DM, Miao Y, Chinn RJS, et al. MR Imaging evaluation of the activity of Crohn’s disease. AJR 2001;177:1325–1332PubMed Koh DM, Miao Y, Chinn RJS, et al. MR Imaging evaluation of the activity of Crohn’s disease. AJR 2001;177:1325–1332PubMed
38.
Zurück zum Zitat Maccioni F, Viscido A, Broglia L, et al. Evaluation of Crohn’s disease activity with magnetic resonance imaging. Abdom Imaging 2000;25:219–228CrossRefPubMed Maccioni F, Viscido A, Broglia L, et al. Evaluation of Crohn’s disease activity with magnetic resonance imaging. Abdom Imaging 2000;25:219–228CrossRefPubMed
39.
Zurück zum Zitat Best WR, Becktel JM, Singleton JW, Kern F. Development of a Crohn’s disease activity index: National Cooperative Crohn’s Disease Study. Gastroenterology 1976;70:439–444PubMed Best WR, Becktel JM, Singleton JW, Kern F. Development of a Crohn’s disease activity index: National Cooperative Crohn’s Disease Study. Gastroenterology 1976;70:439–444PubMed
40.
Zurück zum Zitat Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, et al. Assessment of Crohn’s disease activity in the small bowel with MR and conventional enteroclysis: preliminary results. Eur Radiol 2004;14:1017–1024CrossRefPubMed Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, et al. Assessment of Crohn’s disease activity in the small bowel with MR and conventional enteroclysis: preliminary results. Eur Radiol 2004;14:1017–1024CrossRefPubMed
41.
Zurück zum Zitat Shoenut JP, Semelka RJ, Silverman R, et al. Magnetic resonance imaging in inflammatory bowel disease. J Clin Gastroenterol 1993;17:73–78PubMed Shoenut JP, Semelka RJ, Silverman R, et al. Magnetic resonance imaging in inflammatory bowel disease. J Clin Gastroenterol 1993;17:73–78PubMed
42.
Zurück zum Zitat Meyers MA, McGuire PV. Spiral CT demonstration of hypervascularity in Crohn’s disease: vascular jejunization of the ileum or the comb sign. Abdom Imaging 1995;20:327–32CrossRefPubMed Meyers MA, McGuire PV. Spiral CT demonstration of hypervascularity in Crohn’s disease: vascular jejunization of the ileum or the comb sign. Abdom Imaging 1995;20:327–32CrossRefPubMed
43.
Zurück zum Zitat Limberg B, Osswald B. Diagnosis and differential diagnosis of ulcerative colitis and Crohn’s disease by hydrocolonic sonography. Am J Gastroenterol Hepatol 1994;89:1051–57 Limberg B, Osswald B. Diagnosis and differential diagnosis of ulcerative colitis and Crohn’s disease by hydrocolonic sonography. Am J Gastroenterol Hepatol 1994;89:1051–57
44.
Zurück zum Zitat Schwerk WB, Beck K, Raith MM, et al. A prospective evaluation of high resolution sonography in the differential diagnosis of inflammatory bowel disease. Am J Gastroenterol Hepatol 1992;4:173–82 Schwerk WB, Beck K, Raith MM, et al. A prospective evaluation of high resolution sonography in the differential diagnosis of inflammatory bowel disease. Am J Gastroenterol Hepatol 1992;4:173–82
45.
Zurück zum Zitat Makanjuola D. Is it Crohn’s disease or intestinal tuberculosis? CT analysis. Eur J Radiol 1998;28:55–61CrossRefPubMed Makanjuola D. Is it Crohn’s disease or intestinal tuberculosis? CT analysis. Eur J Radiol 1998;28:55–61CrossRefPubMed
46.
Zurück zum Zitat Cirillo LC, Camera L, Della Noce M, et al. Accuracy of enteroclysis in Crohn’s disease of the small bowel: a retrospective study. Eur Radiol 2000;10:1894–1898CrossRefPubMed Cirillo LC, Camera L, Della Noce M, et al. Accuracy of enteroclysis in Crohn’s disease of the small bowel: a retrospective study. Eur Radiol 2000;10:1894–1898CrossRefPubMed
47.
Zurück zum Zitat Korman U, Cantasdemir M, Kurugoglu S, et al. Enteroclysis findings of intestinal Behcet disease: a comparative study with Crohn disease. Abdom Imaging 2003;28:308–312CrossRefPubMed Korman U, Cantasdemir M, Kurugoglu S, et al. Enteroclysis findings of intestinal Behcet disease: a comparative study with Crohn disease. Abdom Imaging 2003;28:308–312CrossRefPubMed
48.
Zurück zum Zitat Antes G. [Barium examinations of the small intestine and the colon in inflammatory bowel disease.] Radiologe 2003;43:9–16CrossRefPubMed Antes G. [Barium examinations of the small intestine and the colon in inflammatory bowel disease.] Radiologe 2003;43:9–16CrossRefPubMed
49.
Zurück zum Zitat Nagi B, Sodhi KS, Kochhar R, et al. Small bowel tuberculosis. Abdom Imaging 2004;29:335–340CrossRefPubMed Nagi B, Sodhi KS, Kochhar R, et al. Small bowel tuberculosis. Abdom Imaging 2004;29:335–340CrossRefPubMed
50.
Zurück zum Zitat Suri S, Gupta S, Suri R. Computed tomography in abdominal tuberculosis. Br J Radiol 1999;72:92–98PubMed Suri S, Gupta S, Suri R. Computed tomography in abdominal tuberculosis. Br J Radiol 1999;72:92–98PubMed
51.
Zurück zum Zitat Zhan J, Xia ZS, Zhong YQ, et al. Clinical analysis of primary small intestinal disease: a report of 309 cases. World J Gastroenterol 20041;10:2585–2587PubMed Zhan J, Xia ZS, Zhong YQ, et al. Clinical analysis of primary small intestinal disease: a report of 309 cases. World J Gastroenterol 20041;10:2585–2587PubMed
52.
Zurück zum Zitat Pekmezci S, Altinli E, Saribeyoglu K, et al. Enteroclysis-guided laparoscopic adhesiolysis in recurrent adhesive small bowel obstructions. Surg Laparosc Endosc Percutan Tech 2002;12:165–170CrossRefPubMed Pekmezci S, Altinli E, Saribeyoglu K, et al. Enteroclysis-guided laparoscopic adhesiolysis in recurrent adhesive small bowel obstructions. Surg Laparosc Endosc Percutan Tech 2002;12:165–170CrossRefPubMed
53.
Zurück zum Zitat Gill SS, Heuman DM, Mihas AA. Small intestinal neoplasms. J Clin Gastroenterol 2001;33:267–282CrossRefPubMed Gill SS, Heuman DM, Mihas AA. Small intestinal neoplasms. J Clin Gastroenterol 2001;33:267–282CrossRefPubMed
54.
Zurück zum Zitat Nagi B, Verma V, Vaiphei K, et al. Primary small bowel tumors: a radiologic–pathologic correlation. Abdom Imaging 2001;26:474–480CrossRefPubMed Nagi B, Verma V, Vaiphei K, et al. Primary small bowel tumors: a radiologic–pathologic correlation. Abdom Imaging 2001;26:474–480CrossRefPubMed
55.
Zurück zum Zitat Ipek T, Korman U, Kayabasi B, Eyuboglu E. Closed perforation of the small intestine showing continuity and the diagnostic role of enteroclysis. Hepatogastroenterology 1997;44:161–163PubMed Ipek T, Korman U, Kayabasi B, Eyuboglu E. Closed perforation of the small intestine showing continuity and the diagnostic role of enteroclysis. Hepatogastroenterology 1997;44:161–163PubMed
Metadaten
Titel
Conventional enteroclysis with complementary MR enteroclysis: a combination of small bowel imaging
verfasst von
U. Korman
S. Kurugoglu
G. Ogut
Publikationsdatum
01.10.2005
Erschienen in
Abdominal Radiology / Ausgabe 5/2005
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-005-0331-7

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