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Erschienen in: Abdominal Radiology 5/2012

01.10.2012

Diffusion-weighted MRI: a useful technique to discriminate benign versus malignant ovarian surface epithelial tumors with solid and cystic components

verfasst von: Wenhua Li, Caiting Chu, Yanfen Cui, Ping Zhang, Minjie Zhu

Erschienen in: Abdominal Radiology | Ausgabe 5/2012

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Abstract

Purpose

To evaluate differences in apparent diffusion coefficient (ADC) values for the solid component of benign and malignant ovarian surface epithelial tumors with the goal of differentiating benign versus malignant ovarian tumors preoperatively.

Materials and methods

A total of 127 patients with 131 pelvic masses identified by ultrasound between January 2006 and January 2011 were enrolled in this study. 46 patients were diagnosed with benign tumors, and 85 patients were diagnosed with malignant pathologies. For all of the patients, routine spin-echo MRI and diffusion-weighted imaging were performed. ADC values were determined for all of the masses, and the mean ADC values for the benign and malignant tumors were analyzed using Student’s t test. A P value <0.05 was considered statistically significant.

Results

Mean ADC values associated with malignant ovarian surface epithelial tumors were significantly lower than the mean ADC values of the benign tumors. In addition, the range of ADC values associated with a 95% confidence interval did not overlap between the two groups. ROC analysis indicated that a cutoff ADC value of 1.25 × 10−3 mm2/s was associated with 90.1% sensitivity and 89.9% specificity.

Conclusion

ADC values determined from 1.5 T MR DWI of benign and malignant ovarian masses were found to be significantly different.
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Metadaten
Titel
Diffusion-weighted MRI: a useful technique to discriminate benign versus malignant ovarian surface epithelial tumors with solid and cystic components
verfasst von
Wenhua Li
Caiting Chu
Yanfen Cui
Ping Zhang
Minjie Zhu
Publikationsdatum
01.10.2012
Verlag
Springer US
Erschienen in
Abdominal Radiology / Ausgabe 5/2012
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-011-9814-x

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