Erschienen in:
01.08.2015 | Case Report
68Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer
verfasst von:
Matthias Eiber, Stephan G. Nekolla, Tobias Maurer, Gregor Weirich, Hans-Jürgen Wester, Markus Schwaiger
Erschienen in:
Abdominal Radiology
|
Ausgabe 6/2015
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Abstract
Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a 68Gallium-labeled ligand of the prostate-specific membrane antigen (68Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results.
Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric 68Ga-PSMA PET/MR by combining molecular and structural information.