Skip to main content
Erschienen in: Abdominal Radiology 7/2015

01.10.2015 | Review Article

Quantitative assessment of solid renal masses by contrast-enhanced ultrasound with time–intensity curves: how we do it

verfasst von: Kevin G. King, Mittul Gulati, Harshawn Malhi, Darryl Hwang, Inderbir S. Gill, Phillip M. Cheng, Edward G. Grant, Vinay A. Duddalwar

Erschienen in: Abdominal Radiology | Ausgabe 7/2015

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To discuss the evaluation of the enhancement curve over time of the major renal cell carcinoma (RCC) subtypes, oncocytoma, and lipid-poor angiomyolipoma, to aid in the preoperative differentiation of these entities. Differentiation of these lesions is important, given the different prognoses of the subtypes, as well as the desire to avoid resecting benign lesions.

Methods

We discuss findings from CT, MR, and US, but with a special emphasis on contrast-enhanced ultrasound (CEUS). CEUS technique is described, as well as time–intensity curve analysis.

Results

Examples of each of the major RCC subtypes (clear cell, papillary, and chromophobe) are shown, as well as examples of oncocytoma and lipid-poor angiomyolipoma. For each lesion, the time–intensity curve of enhancement on CEUS is reviewed, and correlated with the enhancement curve over time reported for multiphase CT and MR.

Conclusions

Preoperative differentiation of the most common solid renal masses is important, and the time–intensity curves of these lesions show some distinguishing features that can aid in this differentiation. The use of CEUS is increasing, and as a modality it is especially well suited to the evaluation of the time–intensity curve.
Literatur
2.
Zurück zum Zitat Kutikov A, Fossett LK, Ramchandani P, et al. (2006) Incidence of benign pathologic findings at partial nephrectomy for solitary renal mass presumed to be renal cell carcinoma on preoperative imaging. Urology 68(4):737–740CrossRefPubMed Kutikov A, Fossett LK, Ramchandani P, et al. (2006) Incidence of benign pathologic findings at partial nephrectomy for solitary renal mass presumed to be renal cell carcinoma on preoperative imaging. Urology 68(4):737–740CrossRefPubMed
3.
Zurück zum Zitat Remzi M, Ozsoy M, Klingler HC, et al. (2006) Are small renal tumors harmless? Analysis of histopathological features according to tumors 4 cm or less in diameter. J Urol 176(3):896–899CrossRefPubMed Remzi M, Ozsoy M, Klingler HC, et al. (2006) Are small renal tumors harmless? Analysis of histopathological features according to tumors 4 cm or less in diameter. J Urol 176(3):896–899CrossRefPubMed
4.
Zurück zum Zitat Fujii Y, Komai Y, Saito K, et al. (2008) Incidence of benign pathologic lesions at partial nephrectomy for presumed RCC renal masses: Japanese dual-center experience with 176 consecutive patients. Urology 72(3):598–602CrossRefPubMed Fujii Y, Komai Y, Saito K, et al. (2008) Incidence of benign pathologic lesions at partial nephrectomy for presumed RCC renal masses: Japanese dual-center experience with 176 consecutive patients. Urology 72(3):598–602CrossRefPubMed
5.
Zurück zum Zitat Jeon HG, Lee SR, Kim KH, et al. (2010) Benign lesions after partial nephrectomy for presumed renal cell carcinoma in masses 4 cm or less: prevalence and predictors in Korean patients. Urology 76(3):574–579CrossRefPubMed Jeon HG, Lee SR, Kim KH, et al. (2010) Benign lesions after partial nephrectomy for presumed renal cell carcinoma in masses 4 cm or less: prevalence and predictors in Korean patients. Urology 76(3):574–579CrossRefPubMed
6.
Zurück zum Zitat Sasiwimonphan K, Takahashi N, Leibovich BC, et al. (2012) Small (<4 cm) renal mass: differentiation of angiomyolipoma without visible fat from renal cell carcinoma utilizing MR imaging. Radiology 263(1):160–168CrossRefPubMed Sasiwimonphan K, Takahashi N, Leibovich BC, et al. (2012) Small (<4 cm) renal mass: differentiation of angiomyolipoma without visible fat from renal cell carcinoma utilizing MR imaging. Radiology 263(1):160–168CrossRefPubMed
7.
Zurück zum Zitat Hindman N, Ngo L, Genega EM, et al. (2012) Angiomyolipoma with minimal fat: can it be differentiated from clear cell renal cell carcinoma by using standard MR techniques? Radiology 265(2):468–477PubMedCentralCrossRefPubMed Hindman N, Ngo L, Genega EM, et al. (2012) Angiomyolipoma with minimal fat: can it be differentiated from clear cell renal cell carcinoma by using standard MR techniques? Radiology 265(2):468–477PubMedCentralCrossRefPubMed
8.
Zurück zum Zitat Prasad SR, Humphrey PA, Catena JR, et al. (2006) Common and uncommon histologic subtypes of renal cell carcinoma: imaging spectrum with pathologic correlation. Radiographics 26(6):1795–1806CrossRefPubMed Prasad SR, Humphrey PA, Catena JR, et al. (2006) Common and uncommon histologic subtypes of renal cell carcinoma: imaging spectrum with pathologic correlation. Radiographics 26(6):1795–1806CrossRefPubMed
9.
Zurück zum Zitat Crumley SM, Divatia M, Truong L, et al. (2013) Renal cell carcinoma: Evolving and emerging subtypes. World J Clin Cases 1(9):262–275PubMedCentralPubMed Crumley SM, Divatia M, Truong L, et al. (2013) Renal cell carcinoma: Evolving and emerging subtypes. World J Clin Cases 1(9):262–275PubMedCentralPubMed
10.
Zurück zum Zitat Shuch B, Amin A, Armstrong AJ, et al. (2015) Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity. Eur Urol 67(1):85–97CrossRefPubMed Shuch B, Amin A, Armstrong AJ, et al. (2015) Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity. Eur Urol 67(1):85–97CrossRefPubMed
11.
Zurück zum Zitat Ng CS, Wood CG, Silverman PM, et al. (2008) Renal cell carcinoma: diagnosis, staging, and surveillance. Am J Roentgenol 191(4):1220–1232CrossRef Ng CS, Wood CG, Silverman PM, et al. (2008) Renal cell carcinoma: diagnosis, staging, and surveillance. Am J Roentgenol 191(4):1220–1232CrossRef
12.
Zurück zum Zitat Gerst S, Hann LE, Li D, et al. (2011) Evaluation of renal masses with contrast-enhanced ultrasound: initial experience. Am J Roentgenol 197(4):897–906CrossRef Gerst S, Hann LE, Li D, et al. (2011) Evaluation of renal masses with contrast-enhanced ultrasound: initial experience. Am J Roentgenol 197(4):897–906CrossRef
13.
Zurück zum Zitat Jinzaki M, Tanimoto A, Mukai M, et al. (2000) Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathologic findings and tumor angiogenesis. J Comput Assist Tomogr 24(6):835–842CrossRefPubMed Jinzaki M, Tanimoto A, Mukai M, et al. (2000) Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathologic findings and tumor angiogenesis. J Comput Assist Tomogr 24(6):835–842CrossRefPubMed
14.
Zurück zum Zitat MacLennan GT, Bostwick DG (1995) Microvessel density in renal cell carcinoma: lack of prognostic significance. Urology 46(1):27–30CrossRefPubMed MacLennan GT, Bostwick DG (1995) Microvessel density in renal cell carcinoma: lack of prognostic significance. Urology 46(1):27–30CrossRefPubMed
17.
Zurück zum Zitat Correas JM, Bridal L, Lesavre A, et al. (2001) Ultrasound contrast agents: properties, principles of action, tolerance, and artifacts. Eur Radiol 11(8):1316–1328CrossRefPubMed Correas JM, Bridal L, Lesavre A, et al. (2001) Ultrasound contrast agents: properties, principles of action, tolerance, and artifacts. Eur Radiol 11(8):1316–1328CrossRefPubMed
18.
Zurück zum Zitat McArthur C, Baxter GM (2012) Current and potential renal applications of contrast-enhanced ultrasound. Clin Radiol 67(9):909–922CrossRefPubMed McArthur C, Baxter GM (2012) Current and potential renal applications of contrast-enhanced ultrasound. Clin Radiol 67(9):909–922CrossRefPubMed
19.
Zurück zum Zitat Wei K, Mulvagh SL, Carson L, et al. (2008) The safety of definity and optison for ultrasound image enhancement: a retrospective analysis of 78,383 administered contrast doses. J Am Soc Echocardiogr 21(11):1202–1206CrossRefPubMed Wei K, Mulvagh SL, Carson L, et al. (2008) The safety of definity and optison for ultrasound image enhancement: a retrospective analysis of 78,383 administered contrast doses. J Am Soc Echocardiogr 21(11):1202–1206CrossRefPubMed
20.
Zurück zum Zitat Main ML, Goldman JH, Grayburn PA (2007) Thinking outside the “box”—the ultrasound contrast controversy. J Am Coll Cardiol 50(25):2434–2437CrossRefPubMed Main ML, Goldman JH, Grayburn PA (2007) Thinking outside the “box”—the ultrasound contrast controversy. J Am Coll Cardiol 50(25):2434–2437CrossRefPubMed
21.
Zurück zum Zitat Main ML, Hibberd MG, Ryan A, et al. (2014) Acute mortality in critically ill patients undergoing echocardiography with or without an ultrasound contrast agent. JACC Cardiovasc Imaging 7(1):40–48CrossRefPubMed Main ML, Hibberd MG, Ryan A, et al. (2014) Acute mortality in critically ill patients undergoing echocardiography with or without an ultrasound contrast agent. JACC Cardiovasc Imaging 7(1):40–48CrossRefPubMed
22.
Zurück zum Zitat Xue LY, Lu Q, Huang BJ, et al. (2014) Contrast-enhanced ultrasonography for evaluation of cystic renal mass: in comparison to contrast-enhanced CT and conventional ultrasound. Abdom Imaging 39(6):1274–1283CrossRefPubMed Xue LY, Lu Q, Huang BJ, et al. (2014) Contrast-enhanced ultrasonography for evaluation of cystic renal mass: in comparison to contrast-enhanced CT and conventional ultrasound. Abdom Imaging 39(6):1274–1283CrossRefPubMed
23.
Zurück zum Zitat Aoki S, Hattori R, Yamamoto T, et al. (2011) Contrast-enhanced ultrasound using a time–intensity curve for the diagnosis of renal cell carcinoma. BJU Int 108(3):349–354CrossRefPubMed Aoki S, Hattori R, Yamamoto T, et al. (2011) Contrast-enhanced ultrasound using a time–intensity curve for the diagnosis of renal cell carcinoma. BJU Int 108(3):349–354CrossRefPubMed
24.
Zurück zum Zitat Cai Y, Du L, Li F, Gu J, Bai M (2014) Quantification of enhancement of renal parenchymal masses with contrast-enhanced ultrasound. Ultrasound Med Biol 40(7):1387–1393CrossRefPubMed Cai Y, Du L, Li F, Gu J, Bai M (2014) Quantification of enhancement of renal parenchymal masses with contrast-enhanced ultrasound. Ultrasound Med Biol 40(7):1387–1393CrossRefPubMed
25.
Zurück zum Zitat Young JR, Margolis D, Sauk S, et al. (2013) Clear cell renal cell carcinoma: discrimination from other renal cell carcinoma subtypes and oncocytoma at multiphasic multidetector CT. Radiology 267(2):444–453CrossRefPubMed Young JR, Margolis D, Sauk S, et al. (2013) Clear cell renal cell carcinoma: discrimination from other renal cell carcinoma subtypes and oncocytoma at multiphasic multidetector CT. Radiology 267(2):444–453CrossRefPubMed
26.
Zurück zum Zitat Cheville JC, Lohse CM, Zincke H, Weaver AL, Blute ML (2003) Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol 27(5):612–624CrossRefPubMed Cheville JC, Lohse CM, Zincke H, Weaver AL, Blute ML (2003) Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol 27(5):612–624CrossRefPubMed
27.
Zurück zum Zitat Olshan AF, Kuo TM, Meyer AM, et al. (2013) Racial difference in histologic subtype of renal cell carcinoma. Cancer Med 2(5):744–749PubMedCentralPubMed Olshan AF, Kuo TM, Meyer AM, et al. (2013) Racial difference in histologic subtype of renal cell carcinoma. Cancer Med 2(5):744–749PubMedCentralPubMed
28.
29.
Zurück zum Zitat Hagenkord JM, Gatalica Z, Jonasch E, Monzon FA (2011) Clinical genomics of renal epithelial tumors. Cancer Genet 204(6):285–297CrossRefPubMed Hagenkord JM, Gatalica Z, Jonasch E, Monzon FA (2011) Clinical genomics of renal epithelial tumors. Cancer Genet 204(6):285–297CrossRefPubMed
30.
31.
Zurück zum Zitat Polascik TJ, Bostwick DG, Cairns P (2002) Molecular genetics and histopathologic features of adult distal nephron tumors. Urology 60(6):941–946CrossRefPubMed Polascik TJ, Bostwick DG, Cairns P (2002) Molecular genetics and histopathologic features of adult distal nephron tumors. Urology 60(6):941–946CrossRefPubMed
32.
Zurück zum Zitat Sheir KZ, El-Azab M, Mosbah A, El-Baz M, Shaaban AA (2005) Differentiation of renal cell carcinoma subtypes by multislice computerized tomography. J Urol 174(2):451–455CrossRefPubMed Sheir KZ, El-Azab M, Mosbah A, El-Baz M, Shaaban AA (2005) Differentiation of renal cell carcinoma subtypes by multislice computerized tomography. J Urol 174(2):451–455CrossRefPubMed
33.
Zurück zum Zitat Kim JK, Kim TK, Ahn HJ, et al. (2002) Differentiation of subtypes of renal cell carcinoma on helical CT scans. Am J Roentgenol 178(6):1499–1506CrossRef Kim JK, Kim TK, Ahn HJ, et al. (2002) Differentiation of subtypes of renal cell carcinoma on helical CT scans. Am J Roentgenol 178(6):1499–1506CrossRef
34.
Zurück zum Zitat Sun MR, Ngo L, Genega EM, et al. (2009) Renal cell carcinoma: dynamic contrast-enhanced MR imaging for differentiation of tumor subtypes–correlation with pathologic findings. Radiology 250(3):793–802CrossRefPubMed Sun MR, Ngo L, Genega EM, et al. (2009) Renal cell carcinoma: dynamic contrast-enhanced MR imaging for differentiation of tumor subtypes–correlation with pathologic findings. Radiology 250(3):793–802CrossRefPubMed
35.
Zurück zum Zitat Fan L, Lianfang D, Jinfang X, Yijin S, Ying W (2008) Diagnostic efficacy of contrast-enhanced ultrasonography in solid renal parenchymal lesions with maximum diameters of 5 cm. J Ultrasound Med 27(6):875–885PubMed Fan L, Lianfang D, Jinfang X, Yijin S, Ying W (2008) Diagnostic efficacy of contrast-enhanced ultrasonography in solid renal parenchymal lesions with maximum diameters of 5 cm. J Ultrasound Med 27(6):875–885PubMed
36.
Zurück zum Zitat Xu ZF, Xu HX, Xie XY, et al. (2010) Renal cell carcinoma and renal angiomyolipoma: differential diagnosis with real-time contrast-enhanced ultrasonography. J Ultrasound Med 29(5):709–717PubMed Xu ZF, Xu HX, Xie XY, et al. (2010) Renal cell carcinoma and renal angiomyolipoma: differential diagnosis with real-time contrast-enhanced ultrasonography. J Ultrasound Med 29(5):709–717PubMed
37.
Zurück zum Zitat Lu Q, Xue L, Huang B, et al. (2014) Histotype differentiation of hypo-echoic renal tumors on CEUS: usefulness of enhancement homogeneity and intensity. Abdom Imaging. doi:10.1007/s00261-014-0340-5 Lu Q, Xue L, Huang B, et al. (2014) Histotype differentiation of hypo-echoic renal tumors on CEUS: usefulness of enhancement homogeneity and intensity. Abdom Imaging. doi:10.​1007/​s00261-014-0340-5
38.
Zurück zum Zitat Lu Q, Li CX, Huang BJ, Xue LY, Wang WP (2015) Triphasic and epithelioid minimal fat renal angiomyolipoma and clear cell renal cell carcinoma: qualitative and quantitative CEUS characteristics and distinguishing features. Abdom Imaging 40(2):333–342CrossRefPubMed Lu Q, Li CX, Huang BJ, Xue LY, Wang WP (2015) Triphasic and epithelioid minimal fat renal angiomyolipoma and clear cell renal cell carcinoma: qualitative and quantitative CEUS characteristics and distinguishing features. Abdom Imaging 40(2):333–342CrossRefPubMed
39.
Zurück zum Zitat Vikram R, Ng CS, Tamboli P, et al. (2009) Papillary renal cell carcinoma: radiologic–pathologic correlation and spectrum of disease. Radiographics 29(3):741–754CrossRefPubMed Vikram R, Ng CS, Tamboli P, et al. (2009) Papillary renal cell carcinoma: radiologic–pathologic correlation and spectrum of disease. Radiographics 29(3):741–754CrossRefPubMed
40.
Zurück zum Zitat Ruppert-Kohlmayr AJ, Uggowitzer M, Meissnitzer T, Ruppert G (2004) Differentiation of renal clear cell carcinoma and renal papillary carcinoma using quantitative CT enhancement parameters. Am J Roentgenol 183(5):1387–1391CrossRef Ruppert-Kohlmayr AJ, Uggowitzer M, Meissnitzer T, Ruppert G (2004) Differentiation of renal clear cell carcinoma and renal papillary carcinoma using quantitative CT enhancement parameters. Am J Roentgenol 183(5):1387–1391CrossRef
41.
Zurück zum Zitat Herts BR, Coll DM, Novick AC, et al. (2002) Enhancement characteristics of papillary renal neoplasms revealed on triphasic helical CT of the kidneys. Am J Roentgenol 178(2):367–372CrossRef Herts BR, Coll DM, Novick AC, et al. (2002) Enhancement characteristics of papillary renal neoplasms revealed on triphasic helical CT of the kidneys. Am J Roentgenol 178(2):367–372CrossRef
42.
Zurück zum Zitat Zhang J, Lefkowitz RA, Ishill NM, et al. (2007) Solid renal cortical tumors: differentiation with CT. Radiology 244(2):494–504CrossRefPubMed Zhang J, Lefkowitz RA, Ishill NM, et al. (2007) Solid renal cortical tumors: differentiation with CT. Radiology 244(2):494–504CrossRefPubMed
43.
Zurück zum Zitat Scialpi M, Di Maggio A, Midiri M, et al. (2000) Small renal masses: assessment of lesion characterization and vascularity on dynamic contrast-enhanced MR imaging with fat suppression. Am J Roentgenol 175(3):751–757CrossRef Scialpi M, Di Maggio A, Midiri M, et al. (2000) Small renal masses: assessment of lesion characterization and vascularity on dynamic contrast-enhanced MR imaging with fat suppression. Am J Roentgenol 175(3):751–757CrossRef
44.
Zurück zum Zitat Vera-Badillo FE, Conde E, Duran I (2012) Chromophobe renal cell carcinoma: a review of an uncommon entity. Int J Urol 19(10):894–900CrossRefPubMed Vera-Badillo FE, Conde E, Duran I (2012) Chromophobe renal cell carcinoma: a review of an uncommon entity. Int J Urol 19(10):894–900CrossRefPubMed
45.
Zurück zum Zitat Kim JI, Cho JY, Moon KC, Lee HJ, Kim SH (2009) Segmental enhancement inversion at biphasic multidetector CT: characteristic finding of small renal oncocytoma. Radiology 252(2):441–448CrossRefPubMed Kim JI, Cho JY, Moon KC, Lee HJ, Kim SH (2009) Segmental enhancement inversion at biphasic multidetector CT: characteristic finding of small renal oncocytoma. Radiology 252(2):441–448CrossRefPubMed
46.
Zurück zum Zitat Rosenkrantz AB, Hindman N, Fitzgerald EF, et al. (2010) MRI features of renal oncocytoma and chromophobe renal cell carcinoma. Am J Roentgenol 195(6):W421–W427CrossRef Rosenkrantz AB, Hindman N, Fitzgerald EF, et al. (2010) MRI features of renal oncocytoma and chromophobe renal cell carcinoma. Am J Roentgenol 195(6):W421–W427CrossRef
47.
Zurück zum Zitat O’Malley ME, Tran P, Hanbidge A, Rogalla P (2012) Small renal oncocytomas: is segmental enhancement inversion a characteristic finding at biphasic MDCT? Am J Roentgenol 199(6):1312–1315CrossRef O’Malley ME, Tran P, Hanbidge A, Rogalla P (2012) Small renal oncocytomas: is segmental enhancement inversion a characteristic finding at biphasic MDCT? Am J Roentgenol 199(6):1312–1315CrossRef
48.
Zurück zum Zitat Woo S, Cho JY, Kim SH, et al. (2013) Segmental enhancement inversion of small renal oncocytoma: differences in prevalence according to tumor size. Am J Roentgenol 200(5):1054–1059CrossRef Woo S, Cho JY, Kim SH, et al. (2013) Segmental enhancement inversion of small renal oncocytoma: differences in prevalence according to tumor size. Am J Roentgenol 200(5):1054–1059CrossRef
49.
Zurück zum Zitat Schieda N, Al-Subhi M, Flood TA, El-Khodary M, McInnes MD (2014) Diagnostic accuracy of segmental enhancement inversion for the diagnosis of renal oncocytoma using biphasic computed tomography (CT) and multiphase contrast-enhanced magnetic resonance imaging (MRI). Eur Radiol 24(11):2787–2794CrossRefPubMed Schieda N, Al-Subhi M, Flood TA, El-Khodary M, McInnes MD (2014) Diagnostic accuracy of segmental enhancement inversion for the diagnosis of renal oncocytoma using biphasic computed tomography (CT) and multiphase contrast-enhanced magnetic resonance imaging (MRI). Eur Radiol 24(11):2787–2794CrossRefPubMed
50.
Zurück zum Zitat Gakis G, Kramer U, Schilling D, et al. (2011) Small renal oncocytomas: differentiation with multiphase CT. Eur J Radiol 80(2):274–278CrossRefPubMed Gakis G, Kramer U, Schilling D, et al. (2011) Small renal oncocytomas: differentiation with multiphase CT. Eur J Radiol 80(2):274–278CrossRefPubMed
51.
Zurück zum Zitat Tamai H, Takiguchi Y, Oka M, et al. (2005) Contrast-enhanced ultrasonography in the diagnosis of solid renal tumors. J Ultrasound Med 24(12):1635–1640PubMed Tamai H, Takiguchi Y, Oka M, et al. (2005) Contrast-enhanced ultrasonography in the diagnosis of solid renal tumors. J Ultrasound Med 24(12):1635–1640PubMed
52.
Zurück zum Zitat Wu Y, Du L, Li F, et al. (2013) Renal oncocytoma: contrast-enhanced sonographic features. J Ultrasound Med 32(3):441–448PubMed Wu Y, Du L, Li F, et al. (2013) Renal oncocytoma: contrast-enhanced sonographic features. J Ultrasound Med 32(3):441–448PubMed
53.
Zurück zum Zitat Halpenny D, Snow A, McNeill G, Torreggiani WC (2010) The radiological diagnosis and treatment of renal angiomyolipoma-current status. Clin Radiol 65(2):99–108CrossRefPubMed Halpenny D, Snow A, McNeill G, Torreggiani WC (2010) The radiological diagnosis and treatment of renal angiomyolipoma-current status. Clin Radiol 65(2):99–108CrossRefPubMed
54.
Zurück zum Zitat Froemming AT, Boland J, Cheville J, Takahashi N, Kawashima A (2013) Renal epithelioid angiomyolipoma: imaging characteristics in nine cases with radiologic-pathologic correlation and review of the literature. Am J Roentgenol 200(2):W178–W186CrossRef Froemming AT, Boland J, Cheville J, Takahashi N, Kawashima A (2013) Renal epithelioid angiomyolipoma: imaging characteristics in nine cases with radiologic-pathologic correlation and review of the literature. Am J Roentgenol 200(2):W178–W186CrossRef
55.
Zurück zum Zitat Jinzaki M, Silverman SG, Akita H, et al. (2014) Renal angiomyolipoma: a radiological classification and update on recent developments in diagnosis and management. Abdom Imaging 39(3):588–604PubMedCentralCrossRefPubMed Jinzaki M, Silverman SG, Akita H, et al. (2014) Renal angiomyolipoma: a radiological classification and update on recent developments in diagnosis and management. Abdom Imaging 39(3):588–604PubMedCentralCrossRefPubMed
56.
Zurück zum Zitat Chaudhry HS, Davenport MS, Nieman CM, Ho LM, Neville AM (2012) Histogram analysis of small solid renal masses: differentiating minimal fat angiomyolipoma from renal cell carcinoma. Am J Roentgenol 198(2):377–383CrossRef Chaudhry HS, Davenport MS, Nieman CM, Ho LM, Neville AM (2012) Histogram analysis of small solid renal masses: differentiating minimal fat angiomyolipoma from renal cell carcinoma. Am J Roentgenol 198(2):377–383CrossRef
57.
Zurück zum Zitat Kim JK, Park SY, Shon JH, Cho KS (2004) Angiomyolipoma with minimal fat: differentiation from renal cell carcinoma at biphasic helical CT. Radiology 230(3):677–684CrossRefPubMed Kim JK, Park SY, Shon JH, Cho KS (2004) Angiomyolipoma with minimal fat: differentiation from renal cell carcinoma at biphasic helical CT. Radiology 230(3):677–684CrossRefPubMed
58.
Zurück zum Zitat Yang CW, Shen SH, Chang YH, et al. (2013) Are there useful CT features to differentiate renal cell carcinoma from lipid-poor renal angiomyolipoma? Am J Roentgenol 201(5):1017–1028CrossRef Yang CW, Shen SH, Chang YH, et al. (2013) Are there useful CT features to differentiate renal cell carcinoma from lipid-poor renal angiomyolipoma? Am J Roentgenol 201(5):1017–1028CrossRef
Metadaten
Titel
Quantitative assessment of solid renal masses by contrast-enhanced ultrasound with time–intensity curves: how we do it
verfasst von
Kevin G. King
Mittul Gulati
Harshawn Malhi
Darryl Hwang
Inderbir S. Gill
Phillip M. Cheng
Edward G. Grant
Vinay A. Duddalwar
Publikationsdatum
01.10.2015
Verlag
Springer US
Erschienen in
Abdominal Radiology / Ausgabe 7/2015
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-015-0468-y

Weitere Artikel der Ausgabe 7/2015

Abdominal Radiology 7/2015 Zur Ausgabe

Classics in Abdominal Imaging

The wall-echo-shadow (WES) sign

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.