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Erschienen in: International Orthopaedics 6/2006

01.12.2006 | Original Paper

Comparison of the degenerative changes in weight-bearing joints following cementing or grafting techniques in giant cell tumour patients: medium-term results

verfasst von: K. Szalay, I. Antal, J. Kiss, M. Szendroi

Erschienen in: International Orthopaedics | Ausgabe 6/2006

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Abstract

The aim of this retrospective study was to compare and assess the effect of bone grafting and cementing techniques – two common applications used in the treatment of subchondral giant cell tumours of bone (GCTs) – on the development of degenerative changes in the weight-bearing joints of the lower extremity. Eighty patients were included in this follow-up study, 44 of whom underwent curettage followed by bone grafting, and 36 who had curettage followed by cementation. At the 24-month post-operative examination, significantly less degenerative change was found in patients with bone cement than in those with bone grafting. At the 50-month and later (range: 50–148 months) post-operative examination, however, no significant differences were found between the two groups, indicating that there was a significant acceleration of degenerative changes in the cemented group after the 24-month follow-up.
Literatur
1.
Zurück zum Zitat Bini SA, Gill K, Johnston JO (1995) Giant cell tumor of bone. Curettage and cement reconstruction. Clin Ortop 321:245–250 Bini SA, Gill K, Johnston JO (1995) Giant cell tumor of bone. Curettage and cement reconstruction. Clin Ortop 321:245–250
2.
Zurück zum Zitat Blackley HR, Wunder JS, Davis AM, White LM, Kandel R, Bell RS (1999) Treatment of giant-cell tumors of long bones with curettage and bone-grafting. J Bone Jt Surg Am 81:811–820 Blackley HR, Wunder JS, Davis AM, White LM, Kandel R, Bell RS (1999) Treatment of giant-cell tumors of long bones with curettage and bone-grafting. J Bone Jt Surg Am 81:811–820
3.
Zurück zum Zitat Campanacci M (1976) Giant cell tumor and chondrosarcoma. Grading, treatment and results. Cancer Res 54:257–261 Campanacci M (1976) Giant cell tumor and chondrosarcoma. Grading, treatment and results. Cancer Res 54:257–261
4.
Zurück zum Zitat Campanacci M, Giunti A, Olmi R (1975) Giant-cell tumours of bone. A study of 209 cases with long term follow-up. Ital J Orthop Traumatol 1:249–277 Campanacci M, Giunti A, Olmi R (1975) Giant-cell tumours of bone. A study of 209 cases with long term follow-up. Ital J Orthop Traumatol 1:249–277
5.
Zurück zum Zitat Chen TH, Su YP, Chen WM (2005) Giant cell tumors of the knee: subchondral bone integrity affects the outcome. Int Orthop 29:30–34PubMedCrossRef Chen TH, Su YP, Chen WM (2005) Giant cell tumors of the knee: subchondral bone integrity affects the outcome. Int Orthop 29:30–34PubMedCrossRef
6.
Zurück zum Zitat Dreinhofer KE, Rydholm A, Bauer HC, Kreicbergs A (1995) Giant-cell tumours with fractue at diagnosis. J Bone Jt Surg Br 77:189–193 Dreinhofer KE, Rydholm A, Bauer HC, Kreicbergs A (1995) Giant-cell tumours with fractue at diagnosis. J Bone Jt Surg Br 77:189–193
7.
Zurück zum Zitat Enneking WF (1987) Modification of the system for functional evaluation of surgical management of musculoskeletal tumors. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 626–639 Enneking WF (1987) Modification of the system for functional evaluation of surgical management of musculoskeletal tumors. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 626–639
8.
Zurück zum Zitat Frassica FJ, Gorski JP, Pritchard DJ, Sim FH, Chao EYS (1993) A comparative analysis of subchondral replacement with polymethylmethacrylate or autologous bone graft in dogs. Clin Orthop Rel Res 293: 339–378 Frassica FJ, Gorski JP, Pritchard DJ, Sim FH, Chao EYS (1993) A comparative analysis of subchondral replacement with polymethylmethacrylate or autologous bone graft in dogs. Clin Orthop Rel Res 293: 339–378
9.
Zurück zum Zitat Hisatome T, Yasunaga Y, Ikuta Y, Fujimoto Y (2002) Effects on articular cartilage of subchondral replacement with polymethylmethacrylate and calcium phosphate cement. J Biomed Mater Res 59:490–498PubMedCrossRef Hisatome T, Yasunaga Y, Ikuta Y, Fujimoto Y (2002) Effects on articular cartilage of subchondral replacement with polymethylmethacrylate and calcium phosphate cement. J Biomed Mater Res 59:490–498PubMedCrossRef
10.
Zurück zum Zitat Hollinger JO, Battistone GC (1986) Biodegradable bone repair materials. Synthetic polymers and ceramics. Clin Ortop 207:290–305 Hollinger JO, Battistone GC (1986) Biodegradable bone repair materials. Synthetic polymers and ceramics. Clin Ortop 207:290–305
11.
Zurück zum Zitat Hopp SG, Dahners LE, Gilbert JA (1989) A study of the mechanical strength of long bone defects treated with various autograft substitutes. An experimental investigation in the rabbit. J Orthop Res 7:579–584PubMedCrossRef Hopp SG, Dahners LE, Gilbert JA (1989) A study of the mechanical strength of long bone defects treated with various autograft substitutes. An experimental investigation in the rabbit. J Orthop Res 7:579–584PubMedCrossRef
12.
Zurück zum Zitat Johnston JO (1987) Treatment of a giant cell tumor by aggressive curettage and packing with bone cement. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 512–515 Johnston JO (1987) Treatment of a giant cell tumor by aggressive curettage and packing with bone cement. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 512–515
13.
Zurück zum Zitat Labs K, Perka C, Schmidt RG (2001) Treatment of stages 2 and 3 giant-cell tumor. Arch Orthop Trauma Surg 121:83–86PubMedCrossRef Labs K, Perka C, Schmidt RG (2001) Treatment of stages 2 and 3 giant-cell tumor. Arch Orthop Trauma Surg 121:83–86PubMedCrossRef
14.
Zurück zum Zitat Liu HS, Wang JW (1998) Treatment of giant cell tumor of bone: a comparison of local curettage and wide resection. Chang Keng I Hsuey 21:37–43 Liu HS, Wang JW (1998) Treatment of giant cell tumor of bone: a comparison of local curettage and wide resection. Chang Keng I Hsuey 21:37–43
15.
Zurück zum Zitat Malawer M, Bickels J, Meller I, Buch RG, Henshaw RM, Kollender Y (1999) Cryosurgery in the treatment of giant cell tumor. Clin Ortop 359:176–188CrossRef Malawer M, Bickels J, Meller I, Buch RG, Henshaw RM, Kollender Y (1999) Cryosurgery in the treatment of giant cell tumor. Clin Ortop 359:176–188CrossRef
16.
Zurück zum Zitat McGough RL, Rutledge J, Lewis V, Lin PP, Yasko AW (2005) Impact severity of local recurrence in giant cell tumor of bone. Clin Orthop Rel Res 438:116–122 McGough RL, Rutledge J, Lewis V, Lin PP, Yasko AW (2005) Impact severity of local recurrence in giant cell tumor of bone. Clin Orthop Rel Res 438:116–122
17.
Zurück zum Zitat Ozaki T, Hillmann A, Lindner N, Winkelmann W (1997) Cementation of primary aneurysmal bone cysts. Clin Orthop Rel Res 337:240–248 Ozaki T, Hillmann A, Lindner N, Winkelmann W (1997) Cementation of primary aneurysmal bone cysts. Clin Orthop Rel Res 337:240–248
18.
Zurück zum Zitat Radin EL, Martin RB, Burr DB, Caterson B, Boyd RD, Goodwin C (1984) Effects of mechanical loading on the tissues of the rabbit knee. J Orthop Res 2:221–234PubMedCrossRef Radin EL, Martin RB, Burr DB, Caterson B, Boyd RD, Goodwin C (1984) Effects of mechanical loading on the tissues of the rabbit knee. J Orthop Res 2:221–234PubMedCrossRef
19.
Zurück zum Zitat Radin EL, Rose RM (1986) Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 213:34–40PubMed Radin EL, Rose RM (1986) Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 213:34–40PubMed
20.
Zurück zum Zitat Turcotte RE, Wunder JS, Isler MH, Bell RS, Schachar N, Masri BA, Moreau G, Davis AM (2002) Giant cell tumor of long bone: a Canadian Sarcoma Group study. Clin Orthop Rel Res 397:248–258 Turcotte RE, Wunder JS, Isler MH, Bell RS, Schachar N, Masri BA, Moreau G, Davis AM (2002) Giant cell tumor of long bone: a Canadian Sarcoma Group study. Clin Orthop Rel Res 397:248–258
21.
Zurück zum Zitat Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short form health survey (SF-36). Med Care 30:473–483PubMedCrossRef Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short form health survey (SF-36). Med Care 30:473–483PubMedCrossRef
22.
Zurück zum Zitat Welch RD, Berry BH, Crawford K, Zhang H, Zobitz M, Bronson D, Krishnan S (2002) Subchondral defects in caprine femora augmented with in situ setting hydroxyapatite cement, polymethylmethacrylate, or autogenous bone graft: biomechanical and histomorhological analysis after two-years. J Orthop Res 20:464–472PubMedCrossRef Welch RD, Berry BH, Crawford K, Zhang H, Zobitz M, Bronson D, Krishnan S (2002) Subchondral defects in caprine femora augmented with in situ setting hydroxyapatite cement, polymethylmethacrylate, or autogenous bone graft: biomechanical and histomorhological analysis after two-years. J Orthop Res 20:464–472PubMedCrossRef
Metadaten
Titel
Comparison of the degenerative changes in weight-bearing joints following cementing or grafting techniques in giant cell tumour patients: medium-term results
verfasst von
K. Szalay
I. Antal
J. Kiss
M. Szendroi
Publikationsdatum
01.12.2006
Verlag
Springer-Verlag
Erschienen in
International Orthopaedics / Ausgabe 6/2006
Print ISSN: 0341-2695
Elektronische ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-006-0190-z

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