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Erschienen in: World Journal of Surgery 11/2009

01.11.2009

Implementing Fast-Track Protocol for Colorectal Surgery: A Prospective Randomized Clinical Trial

verfasst von: Daniela Ionescu, Cornel Iancu, Daniela Ion, Nadim Al-Hajjar, Simona Margarit, Lucian Mocan, Teodora Mocan, Delia Deac, Raluca Bodea, Horatiu Vasian

Erschienen in: World Journal of Surgery | Ausgabe 11/2009

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Abstract

Background

Fast-track protocols are followed by an enhanced recovery, early return to bowel function and to complete nutrition, and a reduced hospital stay. Our study was designed to implement fast-track protocol in our university hospital.

Methods

The 96 consecutive patients with colorectal neoplasm included in the study were randomized in two equal groups: group 1 (FT) included patients undergoing colorectal surgery in a fast-track protocol, and group 2 (C) included patients undergoing colorectal surgery with a conventional care protocol. As with other fast-track protocols, our protocol included carbohydrate fluids load before operation, early mobilization and oral feeding, regular prokinetics, and multimodal postoperative analgesia. Time to restoration of bowel function, to complete mobilization and feeding, length of hospital stay, and incidence of complications and readmissions were monitored.

Results

Time to mobilization, restoring of bowel function, and complete oral feeding were significantly shorter with fast-track protocol (p = 0.001, p = 0.042, and p = 0.01, respectively). Hospital stay also was shorter in the fast-track group (p = 0.001). The incidence of complications did not significantly differ with the study groups.

Conclusions

In our study, fast-track protocol resulted in a shorter time to mobilization, complete feeding, and discharge from hospital. Fast-track protocol did not increase the incidence of complications. However, we consider that our data require further confirmation with powered multicenter national studies.
Literatur
1.
Zurück zum Zitat Kehlet TH, Wilmore DW (2002) Multimodal strategies to improve surgical outcome. Am J Surg 183:630–641PubMedCrossRef Kehlet TH, Wilmore DW (2002) Multimodal strategies to improve surgical outcome. Am J Surg 183:630–641PubMedCrossRef
2.
Zurück zum Zitat Basse L, Raskov HH, Hjort Jakobsen D et al (2002) Accelerated postoperative recovery program after colonic resection improves physical performance, pulmonary function and body composition. Br J Surg 89:446–453PubMedCrossRef Basse L, Raskov HH, Hjort Jakobsen D et al (2002) Accelerated postoperative recovery program after colonic resection improves physical performance, pulmonary function and body composition. Br J Surg 89:446–453PubMedCrossRef
3.
Zurück zum Zitat Basse L, Thorbol JE, Lossl K, Kehlet H (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277PubMedCrossRef Basse L, Thorbol JE, Lossl K, Kehlet H (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277PubMedCrossRef
4.
Zurück zum Zitat Jakobsen DH, Sonne E, Andreasen J, Kehlet TH (2006) Convalescence after colonic surgery with fast-track vs conventional care. Colorectal Dis 8:683–687PubMedCrossRef Jakobsen DH, Sonne E, Andreasen J, Kehlet TH (2006) Convalescence after colonic surgery with fast-track vs conventional care. Colorectal Dis 8:683–687PubMedCrossRef
5.
Zurück zum Zitat Anderson AD, McNaught CE, MacFie J, Tring I, Barker P, Mitchell CJ (2003) Randomized clinical trial of multimodal optimization and standard perioperative surgical care. Br J Surg 90:1497–1504PubMedCrossRef Anderson AD, McNaught CE, MacFie J, Tring I, Barker P, Mitchell CJ (2003) Randomized clinical trial of multimodal optimization and standard perioperative surgical care. Br J Surg 90:1497–1504PubMedCrossRef
6.
Zurück zum Zitat Delaney CP, Zutshi M, Senagore AJ, Remzi FH, Hammel J, Fazio VW (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859PubMedCrossRef Delaney CP, Zutshi M, Senagore AJ, Remzi FH, Hammel J, Fazio VW (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859PubMedCrossRef
7.
8.
Zurück zum Zitat Nygren J, Hausel J, Kehlet H et al (2005) A comparison in five European Centres of case mix clinical management and outcomes following either conventional or fast-track perioperative care in colorectal surgery. Clin Nutr 24:455–461PubMedCrossRef Nygren J, Hausel J, Kehlet H et al (2005) A comparison in five European Centres of case mix clinical management and outcomes following either conventional or fast-track perioperative care in colorectal surgery. Clin Nutr 24:455–461PubMedCrossRef
9.
10.
Zurück zum Zitat Lassen K, Nygren J, Hausel J, Soop M, Andersen J, Kehlet H (2005) Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24:466–477PubMedCrossRef Lassen K, Nygren J, Hausel J, Soop M, Andersen J, Kehlet H (2005) Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24:466–477PubMedCrossRef
11.
Zurück zum Zitat Junghans T, Junghans E, Schwenk W (2007) Results of fast-track rehabilitation in elective colonic surgery. Transfus Altern Transfus Med 9:78–84CrossRef Junghans T, Junghans E, Schwenk W (2007) Results of fast-track rehabilitation in elective colonic surgery. Transfus Altern Transfus Med 9:78–84CrossRef
12.
Zurück zum Zitat Junger M, Herman N, Schoenberg M (2007) Postoperative care in fast-track rehabilitation for elective colonic surgery. Transfus Altern Transfus Med 9:66–77CrossRef Junger M, Herman N, Schoenberg M (2007) Postoperative care in fast-track rehabilitation for elective colonic surgery. Transfus Altern Transfus Med 9:66–77CrossRef
13.
Zurück zum Zitat Scharfenberg M, Rave W, Junghans T, Schwenk W (2007) Fast-track rehabilitation after colonic surgery in elderly patients: is it feasible? Int J Colorectal Dis 22:1469–1474PubMedCrossRef Scharfenberg M, Rave W, Junghans T, Schwenk W (2007) Fast-track rehabilitation after colonic surgery in elderly patients: is it feasible? Int J Colorectal Dis 22:1469–1474PubMedCrossRef
14.
Zurück zum Zitat Basse L, Hijor T, Jakobsen D, Billesbolle P et al (2000) A clinical pathway to accelerate recovery after colonic resection. Am J Surg 232:51–57 Basse L, Hijor T, Jakobsen D, Billesbolle P et al (2000) A clinical pathway to accelerate recovery after colonic resection. Am J Surg 232:51–57
15.
Zurück zum Zitat Wichmann M, Eben R, Angele M, Braundenburg F, Goetz A, Jaunch KW (2007) Fast-track rehabilitation in elective colorectal surgery patients: a prospective clinical imunological single centre study. ANZ J Surg 77:502–507PubMedCrossRef Wichmann M, Eben R, Angele M, Braundenburg F, Goetz A, Jaunch KW (2007) Fast-track rehabilitation in elective colorectal surgery patients: a prospective clinical imunological single centre study. ANZ J Surg 77:502–507PubMedCrossRef
16.
Zurück zum Zitat Gatt M, Anderson ADG, Reddy BS, Hayward-Sampson P, Tring IC, MacFie J (2005) Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. Br J Surg 92:1354–1362PubMedCrossRef Gatt M, Anderson ADG, Reddy BS, Hayward-Sampson P, Tring IC, MacFie J (2005) Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. Br J Surg 92:1354–1362PubMedCrossRef
17.
Zurück zum Zitat Raue W, Hasse O, Junghans T, Scarfenberg M, Muller JM, Schwenk W (2004) Fast-track multimodal rehabilitation program improves outcome after laparoscopic sigmoidectomy. Surg Endosc 18:1463–1468PubMedCrossRef Raue W, Hasse O, Junghans T, Scarfenberg M, Muller JM, Schwenk W (2004) Fast-track multimodal rehabilitation program improves outcome after laparoscopic sigmoidectomy. Surg Endosc 18:1463–1468PubMedCrossRef
18.
Zurück zum Zitat Delaney CP, Fazio VW, Senagore AJ, Robinson B, Halwerson AL, Renzi FH (2001) Fast-track postoperative management protocol for patients with high co-morbidity undergoing complex abdominal and pelvic colorectal surgery. Br J Surg 88:1533–1538PubMedCrossRef Delaney CP, Fazio VW, Senagore AJ, Robinson B, Halwerson AL, Renzi FH (2001) Fast-track postoperative management protocol for patients with high co-morbidity undergoing complex abdominal and pelvic colorectal surgery. Br J Surg 88:1533–1538PubMedCrossRef
19.
20.
Zurück zum Zitat Kehlet H (2006) Future perspectives and research initiatives in fast-track surgery. Langenbeck’s Arch Surg 391:495–498CrossRef Kehlet H (2006) Future perspectives and research initiatives in fast-track surgery. Langenbeck’s Arch Surg 391:495–498CrossRef
21.
Zurück zum Zitat Kehlet H, Buchler M, Beart R, Billingham RP, Williamson R (2006) Care after colonic operation: is it evidence-based? Results from a multinational survey in Europe and United States. J Am Coll Surg 202:45–54PubMedCrossRef Kehlet H, Buchler M, Beart R, Billingham RP, Williamson R (2006) Care after colonic operation: is it evidence-based? Results from a multinational survey in Europe and United States. J Am Coll Surg 202:45–54PubMedCrossRef
22.
Zurück zum Zitat Moher D, Schulz KF, Altman DG (2001) The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. Ann Intern Med 134(8):657–662PubMed Moher D, Schulz KF, Altman DG (2001) The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. Ann Intern Med 134(8):657–662PubMed
23.
Zurück zum Zitat Altman DG, Schulz KF, Moher D, Egger M. Davidoff F, Elbourne D, Gøtzsche PC, Lang T. The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Ann Intern Med 2001;134(8):663–694PubMed Altman DG, Schulz KF, Moher D, Egger M. Davidoff F, Elbourne D, Gøtzsche PC, Lang T. The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Ann Intern Med 2001;134(8):663–694PubMed
Metadaten
Titel
Implementing Fast-Track Protocol for Colorectal Surgery: A Prospective Randomized Clinical Trial
verfasst von
Daniela Ionescu
Cornel Iancu
Daniela Ion
Nadim Al-Hajjar
Simona Margarit
Lucian Mocan
Teodora Mocan
Delia Deac
Raluca Bodea
Horatiu Vasian
Publikationsdatum
01.11.2009
Verlag
Springer-Verlag
Erschienen in
World Journal of Surgery / Ausgabe 11/2009
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-009-0197-x

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