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World Journal of Surgery

Erschienen in:

01.12.2012

Risk Factor of Surgical Site Infection After Pancreaticoduodenectomy

verfasst von: Teiichi Sugiura, Katsuhiko Uesaka, Norio Ohmagari, Hideyuki Kanemoto, Takashi Mizuno

Erschienen in: World Journal of Surgery | Ausgabe 12/2012

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Abstract

Background

Although surgical site infection (SSI) following pancreaticoduodenectomy is a common complication, the risk factors remain unclear.

Patients and methods

A retrospective study of 408 consecutive patients undergoing pancreaticoduodenectomy was conducted and the risk factors for SSI were assessed. The bacterial composition was also analyzed.

Results

Sixty-one patients developed incisional SSI, and 195 developed organ/space SSI. A multivariate analysis identified that length of operation >480 min (odds ratio [OR] 3.22), main pancreatic duct (MPD) ≤3 mm (OR 2.18), and abdominal wall thickness >10 mm (OR 2.16) were significant risk factors for incisional SSI. The development of pancreatic fistula (OR 7.56), use of semi-closed drainage system (OR 3.68), body mass index >23.5 kg/m² (OR 3.04), MPD ≤3 mm (OR 2.21), and length of operation >480 min (OR 1.78) were significantly associated with organ/space SSI. Bacterial isolation at the SSI foci revealed that gut-derived micro-organisms were the predominant bacterial species.

Conclusions

The presence of pancreatic fistula was the strongest risk factor for organ/space SSI. Efforts to reduce the development of pancreatic fistulas, to decrease length of operation, and to use a closed drainage system would decrease the incidence of SSI following pancreaticoduodenectomy. If SSI that requires antibacterial treatment occurs, then the treatment should target enterobacteria.

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Titel: Risk Factor of Surgical Site Infection After Pancreaticoduodenectomy
verfasst von: Teiichi Sugiura
Katsuhiko Uesaka
Norio Ohmagari
Hideyuki Kanemoto
Takashi Mizuno
Publikationsdatum: 01.12.2012
Verlag: Springer-Verlag
Erschienen in: World Journal of Surgery / Ausgabe 12/2012
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-012-1742-6

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Abstract

Background

Patients and methods

Results

Conclusions

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