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Erschienen in: World Journal of Surgery 5/2013

01.05.2013

Structured Synchronous Implementation of an Enhanced Recovery Program in Elective Colonic Surgery in 33 Hospitals in The Netherlands

verfasst von: Freek Gillissen, Christiaan Hoff, José M. C. Maessen, Bjorn Winkens, Jitske H. F. A. Teeuwen, Maarten F. von Meyenfeldt, Cornelis H. C. Dejong

Erschienen in: World Journal of Surgery | Ausgabe 5/2013

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Abstract

Background

It has been clearly shown that after elective colorectal surgery patients benefit from multimodal perioperative care programs. The Dutch Institute for Health Care Improvement started a breakthrough project to implement a multimodal perioperative care program of enhanced recovery after surgery (ERAS). This pre/post noncontrolled study evaluated the success of large-scale implementation of the ERAS program for elective colonic surgery using the breakthrough series.

Methods

A total of 33 hospitals participated in this breakthrough project during 2005–2009. Each hospital performed a retrospective chart review to gather information on traditionally treated patients (pre-ERAS group, n = 1,451). During the subsequent year patients were treated according to the ERAS program (ERAS group, n = 1 034). Outcomes were length of stay (LOS), functional recovery, adherence to the protocol, and determinants of reduced LOS.

Results

Median LOS decreased significantly from 9 to 6 days (p < 0.001). In the ERAS group, functional recovery was reached within 3 days. Adherence to the protocol elements was high during the preoperative and perioperative phases but slightly lower during the postoperative phase. Younger age, female sex, American Society of Anesthesiologists grades I/II, and laparoscopic surgery were associated with decreased LOS. Care elements that positively influenced LOS were cessation of intravenous fluids and mobilization on postoperative day 1 and administration of laxatives postoperatively.

Conclusions

The ERAS program was successfully implemented in one-third of all Dutch hospitals using the breakthrough series. Participating hospitals reduced the LOS by a median 3 days and were able to improve their standard of care in elective colonic surgery.
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Literatur
1.
Zurück zum Zitat Schoetz DJ Jr, Bockler M, Rosenblatt MS et al (1997) “Ideal” length of stay after colectomy: whose ideal? Dis Colon Rectum 40:806–810PubMedCrossRef Schoetz DJ Jr, Bockler M, Rosenblatt MS et al (1997) “Ideal” length of stay after colectomy: whose ideal? Dis Colon Rectum 40:806–810PubMedCrossRef
2.
Zurück zum Zitat Kehlet H, Mogensen T (1999) Hospital stay of 2 days after open sigmoidectomy with a multimodal rehabilitation program. Br J Surg 86:227–230PubMedCrossRef Kehlet H, Mogensen T (1999) Hospital stay of 2 days after open sigmoidectomy with a multimodal rehabilitation program. Br J Surg 86:227–230PubMedCrossRef
3.
Zurück zum Zitat Basse L, Hjort Jakobsen D, Billesbolle P et al (2000) A clinical pathway to accelerate recovery after colonic resection. Ann Surg 232:51–57PubMedCrossRef Basse L, Hjort Jakobsen D, Billesbolle P et al (2000) A clinical pathway to accelerate recovery after colonic resection. Ann Surg 232:51–57PubMedCrossRef
4.
Zurück zum Zitat Basse L, Raskov HH, Hjort Jakobsen D et al (2002) Accelerated postoperative recovery program after colonic resection improves physical performance, pulmonary function and body composition. Br J Surg 89:446–453PubMedCrossRef Basse L, Raskov HH, Hjort Jakobsen D et al (2002) Accelerated postoperative recovery program after colonic resection improves physical performance, pulmonary function and body composition. Br J Surg 89:446–453PubMedCrossRef
5.
Zurück zum Zitat Basse L, Thorbol JE, Lossl K et al (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277 discussion 277–278PubMedCrossRef Basse L, Thorbol JE, Lossl K et al (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277 discussion 277–278PubMedCrossRef
6.
Zurück zum Zitat Kehlet H (1997) Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth 78:606–617PubMedCrossRef Kehlet H (1997) Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth 78:606–617PubMedCrossRef
7.
Zurück zum Zitat Kehlet H (2000) Manipulation of the metabolic response in clinical practice. World J Surg 24:690–695PubMedCrossRef Kehlet H (2000) Manipulation of the metabolic response in clinical practice. World J Surg 24:690–695PubMedCrossRef
8.
Zurück zum Zitat Kehlet H, Wilmore DW (2002) Multimodal strategies to improve surgical outcome. Am J Surg 183:630–641PubMedCrossRef Kehlet H, Wilmore DW (2002) Multimodal strategies to improve surgical outcome. Am J Surg 183:630–641PubMedCrossRef
9.
Zurück zum Zitat Varadhan KK, Neal KR, Dejong CH et al (2010) The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 29:434–440PubMedCrossRef Varadhan KK, Neal KR, Dejong CH et al (2010) The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 29:434–440PubMedCrossRef
10.
Zurück zum Zitat Bradshaw BG, Liu SS, Thirlby RC (1998) Standardized perioperative care protocols and reduced length of stay after colon surgery. J Am Coll Surg 186:501–506PubMedCrossRef Bradshaw BG, Liu SS, Thirlby RC (1998) Standardized perioperative care protocols and reduced length of stay after colon surgery. J Am Coll Surg 186:501–506PubMedCrossRef
11.
Zurück zum Zitat Schwenk W (2001) Perioperative management influences the results of laparoscopic colonis surgery: arguments for a fast track program. Presented at the 1st hvidovre symposium on perioperative care—colorectal surgery, Copenhagen Schwenk W (2001) Perioperative management influences the results of laparoscopic colonis surgery: arguments for a fast track program. Presented at the 1st hvidovre symposium on perioperative care—colorectal surgery, Copenhagen
12.
Zurück zum Zitat Henriksen MG, Hansen HV, Hessov I (2002) Early oral nutrition after elective colorectal surgery: influence of balanced analgesia and enforced mobilization. Nutrition 18:263–267PubMedCrossRef Henriksen MG, Hansen HV, Hessov I (2002) Early oral nutrition after elective colorectal surgery: influence of balanced analgesia and enforced mobilization. Nutrition 18:263–267PubMedCrossRef
13.
Zurück zum Zitat Anderson AD, McNaught CE, MacFie J et al (2003) Randomized clinical trial of multimodal optimization and standard perioperative surgical care. Br J Surg 90:1497–1504PubMedCrossRef Anderson AD, McNaught CE, MacFie J et al (2003) Randomized clinical trial of multimodal optimization and standard perioperative surgical care. Br J Surg 90:1497–1504PubMedCrossRef
14.
Zurück zum Zitat Delaney CP, Zutshi M, Senagore AJ et al (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859PubMedCrossRef Delaney CP, Zutshi M, Senagore AJ et al (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859PubMedCrossRef
15.
Zurück zum Zitat Soop M, Carlson GL, Hopkinson J et al (2004) Randomized clinical trial of the effects of immediate enteral nutrition on metabolic responses to major colorectal surgery in an enhanced recovery protocol. Br J Surg 91:1138–1145PubMedCrossRef Soop M, Carlson GL, Hopkinson J et al (2004) Randomized clinical trial of the effects of immediate enteral nutrition on metabolic responses to major colorectal surgery in an enhanced recovery protocol. Br J Surg 91:1138–1145PubMedCrossRef
16.
Zurück zum Zitat Gatt M, Anderson AD, Reddy BS et al (2005) Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. Br J Surg 92:1354–1362PubMedCrossRef Gatt M, Anderson AD, Reddy BS et al (2005) Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. Br J Surg 92:1354–1362PubMedCrossRef
17.
Zurück zum Zitat Maessen J, Dejong CH, Hausel J et al (2007) A protocol is not enough to implement an enhanced recovery program for colorectal resection. Br J Surg 94:224–231PubMedCrossRef Maessen J, Dejong CH, Hausel J et al (2007) A protocol is not enough to implement an enhanced recovery program for colorectal resection. Br J Surg 94:224–231PubMedCrossRef
18.
Zurück zum Zitat Lassen K, Soop M, Nygren J et al (2009) Consensus review of optimal perioperative care in colorectal surgery: enhanced recovery after surgery (ERAS) group recommendations. Arch Surg 144:961–969PubMedCrossRef Lassen K, Soop M, Nygren J et al (2009) Consensus review of optimal perioperative care in colorectal surgery: enhanced recovery after surgery (ERAS) group recommendations. Arch Surg 144:961–969PubMedCrossRef
19.
Zurück zum Zitat Lassen K, Hannemann P, Ljungqvist O et al (2005) Patterns in current perioperative practice: survey of colorectal surgeons in five northern European countries. BMJ 330:1420–1421PubMedCrossRef Lassen K, Hannemann P, Ljungqvist O et al (2005) Patterns in current perioperative practice: survey of colorectal surgeons in five northern European countries. BMJ 330:1420–1421PubMedCrossRef
20.
Zurück zum Zitat Nygren J, Hausel J, Kehlet H et al (2005) A comparison in five European centres of case mix, clinical management and outcomes following either conventional or fast-track perioperative care in colorectal surgery. Clin Nutr 24:455–461PubMedCrossRef Nygren J, Hausel J, Kehlet H et al (2005) A comparison in five European centres of case mix, clinical management and outcomes following either conventional or fast-track perioperative care in colorectal surgery. Clin Nutr 24:455–461PubMedCrossRef
21.
Zurück zum Zitat Hannemann P, Lassen K, Hausel J et al (2006) Patterns in current anaesthesiological peri-operative practice for colonic resections: a survey in five northern-European countries. Acta Anaesthesiol Scand 50:1152–1160PubMedCrossRef Hannemann P, Lassen K, Hausel J et al (2006) Patterns in current anaesthesiological peri-operative practice for colonic resections: a survey in five northern-European countries. Acta Anaesthesiol Scand 50:1152–1160PubMedCrossRef
22.
Zurück zum Zitat Polle SW, Wind J, Fuhring JW et al (2007) Implementation of a fast-track perioperative care program: what are the difficulties? Dig Surg 24:441–449PubMedCrossRef Polle SW, Wind J, Fuhring JW et al (2007) Implementation of a fast-track perioperative care program: what are the difficulties? Dig Surg 24:441–449PubMedCrossRef
23.
Zurück zum Zitat Grimshaw JM, Eccles MP, Walker AE et al (2002) Changing physicians’ behavior: what works and thoughts on getting more things to work. J Contin Educ Health Prof 22:237–243PubMedCrossRef Grimshaw JM, Eccles MP, Walker AE et al (2002) Changing physicians’ behavior: what works and thoughts on getting more things to work. J Contin Educ Health Prof 22:237–243PubMedCrossRef
24.
Zurück zum Zitat Grol R, Wensing M (2004) What drives change? Barriers to and incentives for achieving evidence-based practice. Med J Aust 180(6 Suppl):S57–S60PubMed Grol R, Wensing M (2004) What drives change? Barriers to and incentives for achieving evidence-based practice. Med J Aust 180(6 Suppl):S57–S60PubMed
25.
Zurück zum Zitat Wilson KD, Kurz RS (2008) Bridging implementation and institutionalization within organizations: proposed employment of continuous quality improvement to further dissemination. J Public Health Manag Pract 14:109–116PubMed Wilson KD, Kurz RS (2008) Bridging implementation and institutionalization within organizations: proposed employment of continuous quality improvement to further dissemination. J Public Health Manag Pract 14:109–116PubMed
26.
Zurück zum Zitat Fearon KC, Ljungqvist O, Von Meyenfeldt M et al (2005) Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24:466–477PubMedCrossRef Fearon KC, Ljungqvist O, Von Meyenfeldt M et al (2005) Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24:466–477PubMedCrossRef
27.
Zurück zum Zitat Kilo CM (1998) A framework for collaborative improvement: lessons from the Institute for Healthcare Improvement’s Breakthrough Series. Qual Manag Health Care 6:1–13PubMed Kilo CM (1998) A framework for collaborative improvement: lessons from the Institute for Healthcare Improvement’s Breakthrough Series. Qual Manag Health Care 6:1–13PubMed
28.
Zurück zum Zitat Schouten LM, Hulscher ME, van Everdingen JJ et al (2008) Evidence for the impact of quality improvement collaboratives: systematic review. BMJ 336:1491–1494PubMedCrossRef Schouten LM, Hulscher ME, van Everdingen JJ et al (2008) Evidence for the impact of quality improvement collaboratives: systematic review. BMJ 336:1491–1494PubMedCrossRef
29.
Zurück zum Zitat Maessen JM, Dejong CH, Kessels AG et al (2008) Length of stay: an inappropriate readout of the success of enhanced recovery programs. World J Surg 32:971–975PubMedCrossRef Maessen JM, Dejong CH, Kessels AG et al (2008) Length of stay: an inappropriate readout of the success of enhanced recovery programs. World J Surg 32:971–975PubMedCrossRef
30.
Zurück zum Zitat Tjeerdsma HC, Smout AJ, Akkermans LM (1993) Voluntary suppression of defecation delays gastric emptying. Dig Dis Sci 38:832–836PubMedCrossRef Tjeerdsma HC, Smout AJ, Akkermans LM (1993) Voluntary suppression of defecation delays gastric emptying. Dig Dis Sci 38:832–836PubMedCrossRef
31.
Zurück zum Zitat Hansen CT, Sorensen M, Moller C et al (2007) Effect of laxatives on gastrointestinal functional recovery in fast-track hysterectomy: a double-blind, placebo-controlled randomized study. Am J Obstet Gynecol 196:e311–e317CrossRef Hansen CT, Sorensen M, Moller C et al (2007) Effect of laxatives on gastrointestinal functional recovery in fast-track hysterectomy: a double-blind, placebo-controlled randomized study. Am J Obstet Gynecol 196:e311–e317CrossRef
32.
Zurück zum Zitat Hendry PO, van Dam RM, Bukkems SF et al (2010) Randomized clinical trial of laxatives and oral nutritional supplements within an enhanced recovery after surgery protocol following liver resection. Br J Surg 97:1198–1206PubMedCrossRef Hendry PO, van Dam RM, Bukkems SF et al (2010) Randomized clinical trial of laxatives and oral nutritional supplements within an enhanced recovery after surgery protocol following liver resection. Br J Surg 97:1198–1206PubMedCrossRef
33.
Zurück zum Zitat Andersen J, Christensen H, Pachler JH et al (2011) Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study. Colorectal Dis 14:776–782CrossRef Andersen J, Christensen H, Pachler JH et al (2011) Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study. Colorectal Dis 14:776–782CrossRef
34.
Zurück zum Zitat Zingg U, Miskovic D, Pasternak I et al (2008) Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial. Int J Colorectal Dis 23:1175–1183PubMedCrossRef Zingg U, Miskovic D, Pasternak I et al (2008) Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial. Int J Colorectal Dis 23:1175–1183PubMedCrossRef
35.
Zurück zum Zitat Van Bree S, Vlug M, Bemelman W et al (2011) Faster recovery of gastrointestinal transit after laparoscopy and fast-track care in patients undergoing colonic surgery. Gastroenterology 141(872–880):e871–e874 Van Bree S, Vlug M, Bemelman W et al (2011) Faster recovery of gastrointestinal transit after laparoscopy and fast-track care in patients undergoing colonic surgery. Gastroenterology 141(872–880):e871–e874
36.
Zurück zum Zitat Vlug MS, Wind J, Hollmann MW et al (2011) Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study). Ann Surg 254:868–875PubMedCrossRef Vlug MS, Wind J, Hollmann MW et al (2011) Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study). Ann Surg 254:868–875PubMedCrossRef
Metadaten
Titel
Structured Synchronous Implementation of an Enhanced Recovery Program in Elective Colonic Surgery in 33 Hospitals in The Netherlands
verfasst von
Freek Gillissen
Christiaan Hoff
José M. C. Maessen
Bjorn Winkens
Jitske H. F. A. Teeuwen
Maarten F. von Meyenfeldt
Cornelis H. C. Dejong
Publikationsdatum
01.05.2013
Verlag
Springer-Verlag
Erschienen in
World Journal of Surgery / Ausgabe 5/2013
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-013-1938-4

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