Skip to main content
Erschienen in: World Journal of Surgery 5/2015

01.05.2015 | Original Scientific Report

Tracheobronchial Fistula During the Perioperative Period of Esophagectomy for Esophageal Cancer

verfasst von: Masaru Morita, Hiroshi Saeki, Tatsuro Okamoto, Eiji Oki, Sei Yoshida, Yoshihiko Maehara

Erschienen in: World Journal of Surgery | Ausgabe 5/2015

Einloggen, um Zugang zu erhalten

Abstract

Background

Tracheobronchial (TB) injury and fistula formation during the perioperative period of esophagectomy is a rare but life-threatening complication.

Methods

We examined the development of intraoperative TB injury and postoperative TB fistulas in consecutive 763 patients with esophageal cancer who underwent esophagectomy, including 494 patients who underwent transthoracic subtotal esophagectomy.

Results

TB injury and fistulas developed in two (0.4 %) and four patients (0.8 %), respectively, who received transthoracic esophagectomy. TB injury developed during the dissection of a tumor invading a major airway. Direct suturing of the laceration and covering it using a muscle flap was effective for one patient, while additional repair with a major pectoral muscle flap was needed in another patient. Postoperative TB fistulas developed due to peri-tracheal infection in two patients, and conservative treatment with drainage was performed. In another two patients, gastro-tracheal fistulas developed due to mechanical compression of staplers on the gastric tube, which was elevated via the posterior mediastinal route. The direct repair of the gastric tube and covering it with a major pectoral muscle flap resulted in the resolution of these fistulas.

Conclusion

Careful dissection with direct vision of the esophagus, as well as oversewing of the staplers on the gastric tube, is mandatory for preventing TB injury and fistula formation. Appropriate drainage is effective in cases with peri-tracheal abscesses. If the TB fistula fails to heal within a 4- to 6-week period, conservative management should be abandoned. Direct surgical intervention with coverage by a muscle flap is important for TB fistulas.
Literatur
1.
Zurück zum Zitat Hulscher JB, ter Hofstede E, Kloek J et al (2000) Injury to the major airways during subtotal esophagectomy: incidence, management, and sequelae. J Thorac Cardiovasc Surg 120:1093–1096CrossRefPubMed Hulscher JB, ter Hofstede E, Kloek J et al (2000) Injury to the major airways during subtotal esophagectomy: incidence, management, and sequelae. J Thorac Cardiovasc Surg 120:1093–1096CrossRefPubMed
2.
Zurück zum Zitat Orringer MB, Marshall B, Chang AC et al (2007) Two thousand transhiatal esophagectomies: changing trends, lessons learned. Ann Surg 246:363–372 (discussion 372–364)CrossRefPubMedCentralPubMed Orringer MB, Marshall B, Chang AC et al (2007) Two thousand transhiatal esophagectomies: changing trends, lessons learned. Ann Surg 246:363–372 (discussion 372–364)CrossRefPubMedCentralPubMed
3.
Zurück zum Zitat Gupta V, Gupta R, Thingnam SK et al (2009) Major airway injury during esophagectomy: experience at a tertiary care center. J Gastrointest Surg 13:438–441CrossRefPubMed Gupta V, Gupta R, Thingnam SK et al (2009) Major airway injury during esophagectomy: experience at a tertiary care center. J Gastrointest Surg 13:438–441CrossRefPubMed
4.
Zurück zum Zitat Bartels HE, Stein HJ, Siewert JR (1998) Tracheobronchial lesions following oesophagectomy: prevalence, predisposing factors and outcome. Br J Surg 85:403–406CrossRefPubMed Bartels HE, Stein HJ, Siewert JR (1998) Tracheobronchial lesions following oesophagectomy: prevalence, predisposing factors and outcome. Br J Surg 85:403–406CrossRefPubMed
5.
Zurück zum Zitat Marty-Ane CH, Prudhome M, Fabre JM et al (1995) Tracheoesophagogastric anastomosis fistula: a rare complication of esophagectomy. Ann Thorac Surg 60:690–693CrossRefPubMed Marty-Ane CH, Prudhome M, Fabre JM et al (1995) Tracheoesophagogastric anastomosis fistula: a rare complication of esophagectomy. Ann Thorac Surg 60:690–693CrossRefPubMed
6.
Zurück zum Zitat Gitter R, Daniel TM, Kesser BW et al (1999) Membranous tracheobronchial injury repaired with gastric serosal patch. Ann Thorac Surg 67:1159–1160CrossRefPubMed Gitter R, Daniel TM, Kesser BW et al (1999) Membranous tracheobronchial injury repaired with gastric serosal patch. Ann Thorac Surg 67:1159–1160CrossRefPubMed
7.
Zurück zum Zitat Buskens CJ, Hulscher JB, Fockens P et al (2001) Benign tracheo-neo-esophageal fistulas after subtotal esophagectomy. Ann Thorac Surg 72:221–224CrossRefPubMed Buskens CJ, Hulscher JB, Fockens P et al (2001) Benign tracheo-neo-esophageal fistulas after subtotal esophagectomy. Ann Thorac Surg 72:221–224CrossRefPubMed
8.
Zurück zum Zitat Buskens CJ, van Coevorden F, Obertop H, van Lanschot JJ (2002) Disturbed anastomotic healing after esophagectomy: a novel treatment of a benign tracheo-neo-esophageal fistula. Dig Surg 19:88–91CrossRefPubMed Buskens CJ, van Coevorden F, Obertop H, van Lanschot JJ (2002) Disturbed anastomotic healing after esophagectomy: a novel treatment of a benign tracheo-neo-esophageal fistula. Dig Surg 19:88–91CrossRefPubMed
9.
Zurück zum Zitat Koga T, Morita M, Nishida K et al (2008) Successful treatment of tracheomediastinal fistula after tracheal injury obtained during esophagectomy using the pectoralis major muscle: a case report. Esophagus 5:41–44CrossRef Koga T, Morita M, Nishida K et al (2008) Successful treatment of tracheomediastinal fistula after tracheal injury obtained during esophagectomy using the pectoralis major muscle: a case report. Esophagus 5:41–44CrossRef
10.
Zurück zum Zitat Bakhos C, Alazemi S, Michaud G, DeCamp MM (2010) Staged repair of benign tracheo-neo-esophageal fistula 12 years after esophagectomy for esophageal cancer. Ann Thorac Surg 90:e83–e85CrossRefPubMed Bakhos C, Alazemi S, Michaud G, DeCamp MM (2010) Staged repair of benign tracheo-neo-esophageal fistula 12 years after esophagectomy for esophageal cancer. Ann Thorac Surg 90:e83–e85CrossRefPubMed
11.
Zurück zum Zitat Muniappan A, Wain JC, Wright CD et al (2013) Surgical treatment of nonmalignant tracheoesophageal fistula: a thirty-five year experience. Ann Thorac Surg 95:1141–1146CrossRefPubMed Muniappan A, Wain JC, Wright CD et al (2013) Surgical treatment of nonmalignant tracheoesophageal fistula: a thirty-five year experience. Ann Thorac Surg 95:1141–1146CrossRefPubMed
12.
Zurück zum Zitat Morita M, Yoshida R, Ikeda K et al (2008) Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute. Surgery 143:499–508CrossRefPubMed Morita M, Yoshida R, Ikeda K et al (2008) Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute. Surgery 143:499–508CrossRefPubMed
13.
Zurück zum Zitat Toh Y, Sakaguchi Y, Ikeda O et al (2009) The triangulating stapling technique for cervical esophagogastric anastomosis after esophagectomy. Surg Today 39:201–206CrossRefPubMed Toh Y, Sakaguchi Y, Ikeda O et al (2009) The triangulating stapling technique for cervical esophagogastric anastomosis after esophagectomy. Surg Today 39:201–206CrossRefPubMed
14.
Zurück zum Zitat Morita M, Ikeda K, Sugiyama M et al (2010) Repair using the pectoralis major muscle flap for anastomotic leakage after esophageal reconstruction via the subcutaneous route. Surgery 147:212–218CrossRefPubMed Morita M, Ikeda K, Sugiyama M et al (2010) Repair using the pectoralis major muscle flap for anastomotic leakage after esophageal reconstruction via the subcutaneous route. Surgery 147:212–218CrossRefPubMed
15.
Zurück zum Zitat Maruyama K, Motoyama S, Sato Y et al (2009) Tracheobronchial lesions following esophagectomy: erosions, ulcers, and fistulae, and the predictive value of lymph node-related factors. World J Surg 33:778–784. doi:10.1007/s00268-008-9871-7 CrossRefPubMed Maruyama K, Motoyama S, Sato Y et al (2009) Tracheobronchial lesions following esophagectomy: erosions, ulcers, and fistulae, and the predictive value of lymph node-related factors. World J Surg 33:778–784. doi:10.​1007/​s00268-008-9871-7 CrossRefPubMed
16.
Zurück zum Zitat Shen KR, Allen MS, Cassivi SD et al (2010) Surgical management of acquired nonmalignant tracheoesophageal and bronchoesophageal fistulae. Ann Thorac Surg 90:914–918CrossRefPubMed Shen KR, Allen MS, Cassivi SD et al (2010) Surgical management of acquired nonmalignant tracheoesophageal and bronchoesophageal fistulae. Ann Thorac Surg 90:914–918CrossRefPubMed
17.
Zurück zum Zitat Koshenkov VP, Yakoub D, Livingstone AS, Franceschi D (2014) Tracheobronchial injury in the setting of an esophagectomy for cancer: postoperative discovery a bad omen. J Surg Oncol 109:804–807CrossRefPubMed Koshenkov VP, Yakoub D, Livingstone AS, Franceschi D (2014) Tracheobronchial injury in the setting of an esophagectomy for cancer: postoperative discovery a bad omen. J Surg Oncol 109:804–807CrossRefPubMed
18.
Zurück zum Zitat Yasuda T, Sugimura K, Yamasaki M et al (2012) Ten cases of gastro-tracheobronchial fistula: a serious complication after esophagectomy and reconstruction using posterior mediastinal gastric tube. Dis Esophagus 25:687–693CrossRefPubMed Yasuda T, Sugimura K, Yamasaki M et al (2012) Ten cases of gastro-tracheobronchial fistula: a serious complication after esophagectomy and reconstruction using posterior mediastinal gastric tube. Dis Esophagus 25:687–693CrossRefPubMed
19.
Zurück zum Zitat Semlacher RA, Bharadwaj BB, Nixon JA (1994) Management of a post-traumatic tracheo-esophageal fistula following failed primary repair. J Cardiovasc Surg (Torino) 35:83–86 Semlacher RA, Bharadwaj BB, Nixon JA (1994) Management of a post-traumatic tracheo-esophageal fistula following failed primary repair. J Cardiovasc Surg (Torino) 35:83–86
20.
Zurück zum Zitat Chen YY, Chang JM, Lai WW (2012) Tracheo-neo-esophageal fistula caused by exposed metallic staples erosion. Ann Thorac Surg 94:1375CrossRefPubMed Chen YY, Chang JM, Lai WW (2012) Tracheo-neo-esophageal fistula caused by exposed metallic staples erosion. Ann Thorac Surg 94:1375CrossRefPubMed
21.
Zurück zum Zitat Schweigert M, Dubecz A, Beron M et al (2012) Management of anastomotic leakage-induced tracheobronchial fistula following oesophagectomy: the role of endoscopic stent insertion. Eur J Cardiothorac Surg 41:e74–e80CrossRefPubMed Schweigert M, Dubecz A, Beron M et al (2012) Management of anastomotic leakage-induced tracheobronchial fistula following oesophagectomy: the role of endoscopic stent insertion. Eur J Cardiothorac Surg 41:e74–e80CrossRefPubMed
22.
Zurück zum Zitat Freeman RK, Ascioti AJ (2011) Esophageal stent placement for the treatment of perforation, fistula, or anastomotic leak. Semin Thorac Cardiovasc Surg 23:154–158CrossRefPubMed Freeman RK, Ascioti AJ (2011) Esophageal stent placement for the treatment of perforation, fistula, or anastomotic leak. Semin Thorac Cardiovasc Surg 23:154–158CrossRefPubMed
23.
Zurück zum Zitat Martin-Smith JD, Larkin JO, O’Connell F et al (2009) Management of gastro-bronchial fistula complicating a subtotal esophagectomy: a case report. BMC Surg 9:20CrossRefPubMedCentralPubMed Martin-Smith JD, Larkin JO, O’Connell F et al (2009) Management of gastro-bronchial fistula complicating a subtotal esophagectomy: a case report. BMC Surg 9:20CrossRefPubMedCentralPubMed
Metadaten
Titel
Tracheobronchial Fistula During the Perioperative Period of Esophagectomy for Esophageal Cancer
verfasst von
Masaru Morita
Hiroshi Saeki
Tatsuro Okamoto
Eiji Oki
Sei Yoshida
Yoshihiko Maehara
Publikationsdatum
01.05.2015
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 5/2015
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-015-2945-4

Weitere Artikel der Ausgabe 5/2015

World Journal of Surgery 5/2015 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.