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Erschienen in: World Journal of Surgery 5/2016

29.02.2016 | Original Scientific Report

Implementation of Enhanced Recovery After Surgery (ERAS) Across a Provincial Healthcare System: The ERAS Alberta Colorectal Surgery Experience

verfasst von: Gregg Nelson, Lawrence N. Kiyang, Ellen T. Crumley, Anderson Chuck, Thanh Nguyen, Peter Faris, Tracy Wasylak, Carlota Basualdo-Hammond, Susan McKay, Olle Ljungqvist, Leah M. Gramlich

Erschienen in: World Journal of Surgery | Ausgabe 5/2016

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Abstract

Background

Enhanced recovery after surgery (ERAS) colorectal guideline implementation has occurred primarily in standalone institutions worldwide. We implemented the guideline in a single provincial healthcare system, and our study examined the effect of the guideline on patient outcomes [length of stay (LOS), complications, and 30-day post-discharge readmissions] across a healthcare system.

Methods

We compared pre- and post-guideline implementation in consecutive elective colorectal patients, ≥18 years, from six Alberta hospitals between February 2013 and December 2014. Participants were followed up to 30 days post discharge. We used summary statistics, to assess the LOS and complications, and multivariate regression methods to assess readmissions and to estimate cost impacts.

Results

A total of 1333 patients (350 pre- and 983 post-ERAS) were analysed. Of this number, 55 % were males. Median overall guideline compliance was 39 % in pre- and 60 % in post-ERAS patients. Median LOS was 6 days for pre-ERAS compared to 4.5 days in post-ERAS patients with the longest implementation (p value <0.0001). Adjusted risk ratio (RR) was 1.71, 95 % CI 1.09–2.68 for 30-day readmission, comparing pre- to post-ERAS patients. The proportion of patients who developed at least one complication was significantly reduced, from pre- to post-ERAS, difference in proportions = 11.7 %, 95 % CI 2.5–21.0, p value: 0.0139. The net cost savings attributable to guideline implementation ranged between $2806 and $5898 USD per patient.

Conclusion

The findings in our study have shown that ERAS colorectal guideline implementation within a healthcare system resulted in patient outcome improvements, similar to those obtained in smaller standalone implementations. There was a significant beneficial impact of ERAS on scarce health system resources.
Literatur
1.
Zurück zum Zitat Simpson JC, Moonesinghe SR, Grocott MPW et al (2015) Enhanced recovery from surgery in the UK: an audit of the enhanced recovery partnership programme 2009–2012. Br J Anaesth 115(4):560–568CrossRefPubMed Simpson JC, Moonesinghe SR, Grocott MPW et al (2015) Enhanced recovery from surgery in the UK: an audit of the enhanced recovery partnership programme 2009–2012. Br J Anaesth 115(4):560–568CrossRefPubMed
2.
Zurück zum Zitat Gustafsson UO, Scott MJ, Schwenk W et al (2013) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37:259–284. doi:10.1007/s00268-012-1772-0 CrossRefPubMed Gustafsson UO, Scott MJ, Schwenk W et al (2013) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37:259–284. doi:10.​1007/​s00268-012-1772-0 CrossRefPubMed
3.
Zurück zum Zitat Gustafsson UO, Scott MJ, Schwenk W et al (2012) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Clin Nutr 31:783–800CrossRefPubMed Gustafsson UO, Scott MJ, Schwenk W et al (2012) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Clin Nutr 31:783–800CrossRefPubMed
4.
Zurück zum Zitat Nygren J, Thacker J, Carli F et al (2013) Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37:285–305. doi:10.1007/s00268-012-1787-6 CrossRefPubMed Nygren J, Thacker J, Carli F et al (2013) Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37:285–305. doi:10.​1007/​s00268-012-1787-6 CrossRefPubMed
5.
Zurück zum Zitat Nygren J, Thacker J, Carli F et al (2012) Guidelines for perioperative care in elective rectal/pelvic surgery: enhanced recovery after surgery (ERAS®) Society recommendations. Clin Nutr 31:801–816CrossRefPubMed Nygren J, Thacker J, Carli F et al (2012) Guidelines for perioperative care in elective rectal/pelvic surgery: enhanced recovery after surgery (ERAS®) Society recommendations. Clin Nutr 31:801–816CrossRefPubMed
6.
Zurück zum Zitat Walter CJ, Collin J, Dumville JC et al (2009) Enhanced recovery in colorectal resections: a systematic review and meta-analysis. Int J Colorectal Dis 11:344–353CrossRef Walter CJ, Collin J, Dumville JC et al (2009) Enhanced recovery in colorectal resections: a systematic review and meta-analysis. Int J Colorectal Dis 11:344–353CrossRef
7.
Zurück zum Zitat Wind J, Polle SW, Jin PHPFK et al (2006) Systematic review of enhanced recovery programmes in colonic surgery. Br J Surg 93:800–809CrossRefPubMed Wind J, Polle SW, Jin PHPFK et al (2006) Systematic review of enhanced recovery programmes in colonic surgery. Br J Surg 93:800–809CrossRefPubMed
8.
Zurück zum Zitat Gouvas N, Tan E, Windsor A et al (2009) Fast-track vs standard care in colorectal surgery: a meta-analysis update. Int J Colorectal Dis 24:1119–1131CrossRefPubMed Gouvas N, Tan E, Windsor A et al (2009) Fast-track vs standard care in colorectal surgery: a meta-analysis update. Int J Colorectal Dis 24:1119–1131CrossRefPubMed
9.
Zurück zum Zitat Adamina M, Kehlet H, Tomlinson GA et al (2011) Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery. Surgery 149:830–840CrossRefPubMed Adamina M, Kehlet H, Tomlinson GA et al (2011) Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery. Surgery 149:830–840CrossRefPubMed
10.
Zurück zum Zitat Varadhan KK, Neal KR, Dejong CHC et al (2010) The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 29:434–440CrossRefPubMed Varadhan KK, Neal KR, Dejong CHC et al (2010) The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 29:434–440CrossRefPubMed
12.
Zurück zum Zitat Lv L, Y-f Shao, Y-b Zhou (2012) The enhanced recovery after surgery (ERAS) pathway for patients undergoing colorectal surgery: an update of meta-analysis of randomized controlled trials. Int J Colorectal Dis 27:1549–1554CrossRefPubMed Lv L, Y-f Shao, Y-b Zhou (2012) The enhanced recovery after surgery (ERAS) pathway for patients undergoing colorectal surgery: an update of meta-analysis of randomized controlled trials. Int J Colorectal Dis 27:1549–1554CrossRefPubMed
13.
Zurück zum Zitat Eskicioglu C, Forbes S, Aarts M-A et al (2009) Enhanced recovery after surgery (ERAS) programs for patients having colorectal surgery: a meta-analysis of randomized trials. J Gastrointest Surg 13:2321–2329CrossRefPubMed Eskicioglu C, Forbes S, Aarts M-A et al (2009) Enhanced recovery after surgery (ERAS) programs for patients having colorectal surgery: a meta-analysis of randomized trials. J Gastrointest Surg 13:2321–2329CrossRefPubMed
14.
Zurück zum Zitat Roulin D, Donadini A, Gander S et al (2013) Cost-effectiveness of the implementation of an enhanced recovery protocol for colorectal surgery. Br J Surg 100:1108–1114CrossRefPubMed Roulin D, Donadini A, Gander S et al (2013) Cost-effectiveness of the implementation of an enhanced recovery protocol for colorectal surgery. Br J Surg 100:1108–1114CrossRefPubMed
15.
Zurück zum Zitat Lee L, Mata J, Ghitulescu GA et al (2014) Cost-effectiveness of enhanced recovery versus conventional perioperative management for colorectal surgery. Ann Surg 00:1–8 Lee L, Mata J, Ghitulescu GA et al (2014) Cost-effectiveness of enhanced recovery versus conventional perioperative management for colorectal surgery. Ann Surg 00:1–8
16.
Zurück zum Zitat Gillissen F, Hoff C, Maessen JC et al (2013) Structured synchronous implementation of an enhanced recovery program in elective colonic surgery in 33 Hospitals in The Netherlands. World J Surg 37:1082–1093. doi:10.1007/s00268-013-1938-4 CrossRefPubMed Gillissen F, Hoff C, Maessen JC et al (2013) Structured synchronous implementation of an enhanced recovery program in elective colonic surgery in 33 Hospitals in The Netherlands. World J Surg 37:1082–1093. doi:10.​1007/​s00268-013-1938-4 CrossRefPubMed
17.
Zurück zum Zitat Bell GV (2008) Sample size. In: Statistical rules of thumb, vol 36, 2nd edn. John Wiley & Sons Inc., Hoboken, pp 1–14CrossRef Bell GV (2008) Sample size. In: Statistical rules of thumb, vol 36, 2nd edn. John Wiley & Sons Inc., Hoboken, pp 1–14CrossRef
18.
Zurück zum Zitat Vittinghoff E, McCulloch CE (2007) Relaxing the rule of ten events per variable in logistic and Cox regression. Am J Epidemiol 165:710–718CrossRefPubMed Vittinghoff E, McCulloch CE (2007) Relaxing the rule of ten events per variable in logistic and Cox regression. Am J Epidemiol 165:710–718CrossRefPubMed
19.
Zurück zum Zitat Derksen S, Keselman HJ (1992) Backward, forward and stepwise automated subset selection algorithms: frequency of obtaining authentic and noise variables. Br J Math Stat Psychol 45:265–282CrossRef Derksen S, Keselman HJ (1992) Backward, forward and stepwise automated subset selection algorithms: frequency of obtaining authentic and noise variables. Br J Math Stat Psychol 45:265–282CrossRef
20.
Zurück zum Zitat Vlug MS, Wind J, Hollmann MW et al (2011) Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study). Ann Surg 254:868–875CrossRefPubMed Vlug MS, Wind J, Hollmann MW et al (2011) Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study). Ann Surg 254:868–875CrossRefPubMed
21.
Zurück zum Zitat Delaney C, Zutshi M, Senagore A et al (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859CrossRefPubMed Delaney C, Zutshi M, Senagore A et al (2003) Prospective, randomized, controlled trial between a pathway of controlled rehabilitation with early ambulation and diet and traditional postoperative care after laparotomy and intestinal resection. Dis Colon Rectum 46:851–859CrossRefPubMed
23.
Zurück zum Zitat Spanjersberg WR, Van Sambeeck JDP, Bremers A et al (2015) Systematic review and meta-analysis for laparoscopic versus open colon surgery with or without an ERAS programme. Surg Endosc 29(12):3443–3453CrossRefPubMedPubMedCentral Spanjersberg WR, Van Sambeeck JDP, Bremers A et al (2015) Systematic review and meta-analysis for laparoscopic versus open colon surgery with or without an ERAS programme. Surg Endosc 29(12):3443–3453CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Group (2015) The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results from an international registry. Ann Surg 261:1153–1159 Group (2015) The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results from an international registry. Ann Surg 261:1153–1159
25.
Zurück zum Zitat Van Bree S, Vlug M, Bemelman W et al (2011) Original research: faster recovery of gastrointestinal transit after laparoscopy and fast-track care in patients undergoing colonic surgery. Gastroenterology 141:872–880CrossRefPubMed Van Bree S, Vlug M, Bemelman W et al (2011) Original research: faster recovery of gastrointestinal transit after laparoscopy and fast-track care in patients undergoing colonic surgery. Gastroenterology 141:872–880CrossRefPubMed
26.
Zurück zum Zitat Gustafsson UO, Hausel J, Thorell A et al (2011) Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 146:571–577CrossRefPubMed Gustafsson UO, Hausel J, Thorell A et al (2011) Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 146:571–577CrossRefPubMed
27.
Zurück zum Zitat Polle SW, Wind J, Fuhring JW et al (2007) Implementation of a fast-track perioperative care program: what are the difficulties? Dig Surg 24:441–449CrossRefPubMed Polle SW, Wind J, Fuhring JW et al (2007) Implementation of a fast-track perioperative care program: what are the difficulties? Dig Surg 24:441–449CrossRefPubMed
28.
Zurück zum Zitat Ahmed J, Khan S, Lim M et al (2012) Enhanced recovery after surgery protocols—compliance and variations in practice during routine colorectal surgery. Int J Colorectal Dis 14:1045–1051CrossRef Ahmed J, Khan S, Lim M et al (2012) Enhanced recovery after surgery protocols—compliance and variations in practice during routine colorectal surgery. Int J Colorectal Dis 14:1045–1051CrossRef
Metadaten
Titel
Implementation of Enhanced Recovery After Surgery (ERAS) Across a Provincial Healthcare System: The ERAS Alberta Colorectal Surgery Experience
verfasst von
Gregg Nelson
Lawrence N. Kiyang
Ellen T. Crumley
Anderson Chuck
Thanh Nguyen
Peter Faris
Tracy Wasylak
Carlota Basualdo-Hammond
Susan McKay
Olle Ljungqvist
Leah M. Gramlich
Publikationsdatum
29.02.2016
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 5/2016
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-016-3472-7

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