nach oben

CardioVascular and Interventional Radiology

Erschienen in:

01.07.2007 | Review/State of the Art

Radioembolization with ⁹⁰Y Microspheres: Angiographic and Technical Considerations

verfasst von: Robert J. Lewandowski, Kent T. Sato, Bassel Atassi, Robert K. Ryu, Albert A. Nemcek Jr., Laura Kulik, Jean-Francois Geschwind, Ravi Murthy, William Rilling, David Liu, Lourens Bester, Jose Ignacio Bilbao, Andrew S. Kennedy, Reed A. Omary, Riad Salem

Erschienen in: CardioVascular and Interventional Radiology | Ausgabe 4/2007

Einloggen, um Zugang zu erhalten

Abstract

The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-arterial hepatic therapies. Although anatomical variants have been well described, the characterization and understanding of regional hepatic perfusion in the context of radioembolization have not been studied with great depth. The purpose of this review is to provide a thorough discussion and detailed presentation of the angiographic and technical aspects of radioembolization. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. Furthermore, the principles described here apply to all liver-directed transarterial therapies.

El-Serag HB (2002) Hepatocellular carcinoma and hepatitis C in the United States. Hepatology 36:S74–S83PubMedCrossRef

Jemal A, Murray T, Ward E, et al. (2005) Cancer statistics, 2005. CA Cancer J Clin 55:10–30PubMed

Buscarini L, Buscarini E, Di Stasi M, Vallisa D, Quaretti P, Rocca A (2001) Percutaneous radiofrequency ablation of small hepatocellular carcinoma: long-term results. Eur Radiol 11:914–921PubMedCrossRef

Seifert JK, Cozzi PJ, Morris DL (1998) Cryotherapy for neuroendocrine liver metastases. Semin Surg Oncol 14:175–183PubMedCrossRef

Clark TW, Soulen MC (2002) Chemical ablation of hepatocellular carcinoma. J Vasc Interv Radiol 13:S245–S252PubMedCrossRef

Lo CM, Ngan H, Tso WK, et al. (2002) Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma. Hepatology 35:1164–1171PubMedCrossRef

Llovet JM, Real MI, Montana X, et al. (2002) Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet 359:1734–1739PubMedCrossRef

Brown KT, Nevins AB, Getrajdman GI, et al. (1998) Particle embolization for hepatocellular carcinoma. J Vasc Interv Radiol 9:822–828PubMed

MDS Nordion (2004) TheraSphere yttrium-90 microspheres package insert. MDS Nordion, Kanata, Canada

10.

SIRTeX Medical (2004) SIR-Spheres yttrium-90 microspheres package insert, SIRTeX Medical, Lane Cove, Australia

11.

Lawrence TS, Robertson JM, Anscher MS, Jirtle RL, Ensminger WD, Fajardo LF (1995) Hepatic toxicity resulting from cancer treatment. Int J Radiat Oncol Biol Phys 31:1237–1248PubMedCrossRef

12.

Ingold JA, Reed GB, Kaplan HS, Bagshaw MA (1965) Radiation hepatitis. Am J Roentgenol Radium Ther Nucl Med 93:200–208PubMed

13.

Stubbs RS, Cannan RJ, Mitchell AW (2001) Selective internal radiation therapy (SIRT) with 90-yttrium microspheres for extensive colorectal liver metastases. Hepatogastroenterology 48:333–337PubMed

14.

Geschwind JF, Salem R, Carr BI, et al. (2004) Yttrium-90 microspheres for the treatment of hepatocellular carcinoma. Gastroenterology 127:S194–S205PubMedCrossRef

15.

Carr BI (2004) Hepatic arterial 90-yttrium glass microspheres (Therasphere) for unresectable hepatocellular carcinoma: interim safety and survival data on 65 patients. Liver Transpl 10:S107–S110PubMedCrossRef

16.

Gray B, Van Hazel G, Hope M, et al. (2001) Randomised trial of SIR-Spheres plus chemotherapy vs. chemotherapy alone for treating patients with liver metastases from primary large bowel cancer. Ann Oncol 12:1711–1720PubMedCrossRef

17.

Van Hazel G, Blackwell A, Anderson J, et al. (2004) Randomised phase 2 trial of SIR-Spheres plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer. J Surg Oncol 88:78–85PubMedCrossRef

18.

Salem R, Lewandowski RJ, Atassi B, et al. (2005) Treatment of unresectable hepatocellular carcinoma with use of 90Y microspheres (TheraSphere): safety, tumor response, and survival. J Vasc Interv Radiol 16:1627–1639PubMed

19.

Touzios JG, Kiely JM, Pitt SC, et al. (2005) Neuroendocrine hepatic metastases: Does aggressive management improve survival? Ann Surg 241:776–783, discussion 783–775PubMedCrossRef

20.

Romano W (2005) Personal communication. Interventional Radiology, Beaumont Hospital, Royal Oak, MI

21.

Salem R, Thurston KG (2006) Radioembolization with 90yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies: Part 1: Technical and methodologic considerations. J Vasc Interv Radiol 17:1251–1278PubMedCrossRef

22.

Goin JE, Salem R, Carr BI, et al. (2005) Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: factors associated with liver toxicities. J Vasc Interv Radiol 16:205–213PubMed

23.

Goin JE, Salem R, Carr BI, et al. (2005) Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: a risk-stratification analysis. J Vasc Interv Radiol 16:195–203PubMed

24.

Rhee TK, Omary RA, Gates V, et al. (2005) The effect of catheter-directed ct angiography on yttrium-90 radioembolization treatment of hepatocellular carcinoma. J Vasc Interv Radiol 16:1085–1091PubMed

25.

Gray BN (2003) Use of SIR-Spheres in patients with impaired liver function. Safety Notice. Sirtex Medical, Lane Cove, Australia

26.

Salem R, Lewandowski R, Roberts C, et al. (2004) Use of yttrium-90 glass microspheres (TheraSphere) for the treatment of unresectable hepatocellular carcinoma in patients with portal vein thrombosis. J Vasc Interv Radiol 15:335–345PubMed

27.

Murthy R, Xiong H, Nunez R, et al. (2005) Yttrium 90 resin microspheres for the treatment of unresectable colorectal hepatic metastases after failure of multiple chemotherapy regimens: preliminary results. J Vasc Interv Radiol 16:937–945PubMed

28.

Gray BN, Burton MA, Kelleher D, Klemp P, Matz L (1990) Tolerance of the liver to the effects of yttrium-90 radiation. Int J Radiat Oncol Biol Phys 18:619–623PubMed

29.

Murthy R, Nunez R, Szklaruk J, et al. (2005) Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications. Radiographics 25 (Suppl 1):S41–S55PubMedCrossRef

30.

Stubbs RS, Cannan RJ, Mitchell AW (2001) Selective internal radiation therapy with 90yttrium microspheres for extensive colorectal liver metastases. J Gastrointest Surg 5:294–302PubMedCrossRef

31.

Liu DM, Salem R, Bui JT, et al. (2005) Angiographic considerations in patients undergoing liver-directed therapy. J Vasc Interv Radiol 16:911–935PubMed

32.

Covey AM, Brody LA, Maluccio MA, Getrajdman GI, Brown KT (2002) Variant hepatic arterial anatomy revisited: digital subtraction angiography performed in 600 patients. Radiology 224:542–547PubMedCrossRef

33.

Cosin O, Bilbao JI, Alvarez S, de Luis E, Alonso A, Martinez-Cuesta A (2007) Right gastric artery embolization prior to treatment with yttrium-90 microspheres. Cardiovasc Intervent Radiol 30:98–103PubMedCrossRef

34.

Uflacker R, Feldman CJ (1997) Atlas of vascular anatomy: an angiographic approach. Williams & Wilkins, Baltimore

35.

Yip D, Allen R, Ashton C, Jain S (2004) Radiation-induced ulceration of the stomach secondary to hepatic embolization with radioactive yttrium microspheres in the treatment of metastatic colon cancer. J Gastroenterol Hepatol 19:347–349PubMedCrossRef

36.

Goin JE, Dancey JE, Hermann GA, Sickles CJ, Roberts CA, MacDonald JS (2003) Treatment of unresectable metastatic colorectal carcinoma to the liver with intrahepatic Y-90 microspheres: a dose-ranging study. World J Nucl Med 2:216–225

37.

Raju GS, Bardhan KD, Royston C, Beresford J (1999) Giant gastric ulcer: its natural history and outcome in the H2RA era. Am J Gastroenterol 94:3478–3486PubMedCrossRef

38.

Eaden JA, Roberts-Thomson IC (2001) Gastrointestinal: giant gastric ulcers. J Gastroenterol Hepatol 16:573PubMedCrossRef

39.

Arora R, Soulen MC, Haskal ZJ (1999) Cutaneous complications of hepatic chemoembolization via extrahepatic collaterals. J Vasc Interv Radiol 10:1351–1356PubMedCrossRef

40.

Kadir S, Brothers MF (1991) Atlas of normal and variant angiographic anatomy. 1st ed. Saunders, Philadelphia

41.

Lewandowski R, Salem R (2004) Incidence of radiation cholecystitis in patients receiving Y-90 treatment for unresectable liver malignancies. J Vasc Interv Radiol 15:S162

42.

Funaki B (2002) Endovascular intervention for the treatment of acute arterial gastrointestinal hemorrhage. Gastroenterol Clin North Am 31:701–713PubMedCrossRef

43.

Finch IJ (1992) Use of the Palmaz stent in ostial celiac artery stenosis. J Vasc Interv Radiol 3:633–635, discussion 636–637PubMed

44.

Glickerman DJ, Hathaway PB, Hatsukami T, Daly CP, Althaus S, Kohler TR (1997) Transluminal treatment of a celiac artery pseudoaneurysm with a stent graft occlusion device. Cardiovasc Intervent Radiol 20:466–469PubMedCrossRef

45.

Gotsman I, Verstandig A (2001) Intravascular stent implantation of the celiac artery in the treatment of chronic mesenteric ischemia. J Clin Gastroenterol 32:164–166PubMedCrossRef

46.

Razavi M, Chung HH (2004) Endovascular management of chronic mesenteric ischemia. Tech Vasc Interv Radiol 7:155–159PubMedCrossRef

47.

Kim HC, Chung JW, Lee W, Jae HJ, Park JH (2005) Recognizing extrahepatic collateral vessels that supply hepatocellular carcinoma to avoid complications of transcatheter arterial chemoembolization. Radiographics 25 (Suppl 1):S25–S39PubMedCrossRef

48.

Matsumoto AH, Selby JB Jr, Tegtmeyer CJ, et al. (1994) Recent development of rigors during infusion of urokinase: Is it related to an endotoxin? J Vasc Interv Radiol 5:433–438PubMedCrossRef

49.

Salem R, Thurston KG, Carr BI, Goin JE, Geschwind JF (2002) Yttrium-90 microspheres: radiation therapy for unresectable liver cancer. J Vasc Interv Radiol 13:S223–S229PubMedCrossRef

Titel: Radioembolization with 90Y Microspheres: Angiographic and Technical Considerations
verfasst von: Robert J. Lewandowski
Kent T. Sato
Bassel Atassi
Robert K. Ryu
Albert A. Nemcek Jr.
Laura Kulik
Jean-Francois Geschwind
Ravi Murthy
William Rilling
David Liu
Lourens Bester
Jose Ignacio Bilbao
Andrew S. Kennedy
Reed A. Omary
Riad Salem
Publikationsdatum: 01.07.2007
Verlag: Springer-Verlag
Erschienen in: CardioVascular and Interventional Radiology / Ausgabe 4/2007
Print ISSN: 0174-1551
Elektronische ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-007-9064-z

Neu im Fachgebiet Radiologie

08.04.2024 | Andrologie | Nachrichten

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Radioembolization with ⁹⁰Y Microspheres: Angiographic and Technical Considerations

Abstract

Neu im Fachgebiet Radiologie

Wie toxische Männlichkeit der Gesundheit von Männern schadet

Studie bestätigt Potenzial von KI in der Radiologie

Quantitative Angiografie könnte IVUS-Alternative darstellen

Die Ganz-Genom-Sequenzierung startet

Update Radiologie

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2007

Interventional Radiological Management of Prehepatic Obstruction the Splanchnic Venous System

Radiofrequency Ablation in Combination with Embolization in Metachronous Recurrent Renal Cancer in Solitary Kidney after Contralateral Tumor Nephrectomy

Aorto-iliac Endovascular Reconstruction by Kissing Stenting Through Bilateral Brachial Access

The Current Role of Venous Sampling in the Localization of Endocrine Disease

Percutaneous Management of Complications (Aortoenteric Fistula and Sac Abscess) Following Bypass Surgery for Abdominal Aortic Aneurysm

StarClose Vascular Closure Device: Prospective Study on 222 Deployments in an Interventional Radiology Practice

Neu im Fachgebiet Radiologie

Wie toxische Männlichkeit der Gesundheit von Männern schadet

Studie bestätigt Potenzial von KI in der Radiologie

Quantitative Angiografie könnte IVUS-Alternative darstellen

Die Ganz-Genom-Sequenzierung startet

Update Radiologie