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Erschienen in: CardioVascular and Interventional Radiology 12/2018

07.08.2018 | Laboratory Investigation

Effects of Different Mixing Agents on the Stability of Sodium Tetradecyl Sulfate (STS) Foam: An Experimental Study

verfasst von: Kazuki Hashimoto, MD, Barry Uchida, Masahiro Horikawa, Hidefumi Mimura, Khashayar Farsad

Erschienen in: CardioVascular and Interventional Radiology | Ausgabe 12/2018

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Abstract

Purpose

To evaluate the effect of air, CO2 and contrast medium-air on the dwell time (DT) stability of sodium tetradecyl sulfate (STS) foam.

Materials and Methods

Three types of foam sclerosants (air-foam, CO2-foam, contrast-air-foam) were injected eight times into an inclined straight plastic tube (internal diameters 4 mm and 10 mm) filled with a blood substitute. Injections were captured by CCD camera, and images were transferred for digital analysis and calculation of DT.

Results

Contrast-air-foam and air-foam in a 4-mm tube showed 5.6-/3.3-fold greater DT compared to CO2-foam, respectively (P = 0.001). Contrast-air-foam in a 10-mm tube showed 2.1-fold greater DT compared to CO2-foam (P = 0.0167).

Conclusion

A mixture of air and iodinated contrast improves the stability of STS foam compared to mixtures using only air or CO2. Further, animal and clinical studies are needed to validate this in vitro result.
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Literatur
7.
Zurück zum Zitat Pries AR, Neuhaus D, Gaehtgens P. Blood viscosity in tube flow: dependence on diameter and hematocrit. Am J Physiol. 1992;263:H1770–8.PubMed Pries AR, Neuhaus D, Gaehtgens P. Blood viscosity in tube flow: dependence on diameter and hematocrit. Am J Physiol. 1992;263:H1770–8.PubMed
8.
Zurück zum Zitat Johnson LR. Essential medical physiology, 3rd edn. p 293; 2003. Johnson LR. Essential medical physiology, 3rd edn. p 293; 2003.
18.
Zurück zum Zitat Wollmann JC. Sclerosant foams: stabilities, physical properties and rheological behavior. Phlebologie. 2010;39:208–17.CrossRef Wollmann JC. Sclerosant foams: stabilities, physical properties and rheological behavior. Phlebologie. 2010;39:208–17.CrossRef
Metadaten
Titel
Effects of Different Mixing Agents on the Stability of Sodium Tetradecyl Sulfate (STS) Foam: An Experimental Study
verfasst von
Kazuki Hashimoto, MD
Barry Uchida
Masahiro Horikawa
Hidefumi Mimura
Khashayar Farsad
Publikationsdatum
07.08.2018
Verlag
Springer US
Erschienen in
CardioVascular and Interventional Radiology / Ausgabe 12/2018
Print ISSN: 0174-1551
Elektronische ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-018-2049-2

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