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01.05.2007 | Original Article

Fusion of H4/D10S170 to PDGFRβ in a patient with chronic myelomonocytic leukemia and long-term responsiveness to imatinib

verfasst von: Matthias Drechsler, Barbara Hildebrandt, Andrea Kündgen, Ulrich Germing, Brigitte Royer-Pokora

Erschienen in: Annals of Hematology | Ausgabe 5/2007

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Excerpt

Dear Editor, …
Literatur
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Zurück zum Zitat Schwaller J, Anastasiadou E, Cain D, Kutok J, Woyiski S, Willimas IR, LaStarza R, Crescendi B, Sternberg DW, Andreason P, Schiavo R, Siena S, Mecucci C, Gilliland GD (2001) H4(D10S170), a gene frequently rearranged in papillary thyroid carcinomas, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukaemia with t(5;10)(q33;q22). Blood 97:3910–3918PubMedCrossRef Schwaller J, Anastasiadou E, Cain D, Kutok J, Woyiski S, Willimas IR, LaStarza R, Crescendi B, Sternberg DW, Andreason P, Schiavo R, Siena S, Mecucci C, Gilliland GD (2001) H4(D10S170), a gene frequently rearranged in papillary thyroid carcinomas, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukaemia with t(5;10)(q33;q22). Blood 97:3910–3918PubMedCrossRef
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Zurück zum Zitat Kulkarni S, Heath C, Parker S, Chase A, Iqbal A, Pocock F, Kaeda J, Cwynarski K, Goldman JM, Cross NCP (2000) Fusion of H4/D10S170 to the platelet-derived growth factor receptor β in BCR-ABL-negative myeloproliferative disorders with a t(5;10)(q33;q21). Cancer Res 60:3592–3598PubMed Kulkarni S, Heath C, Parker S, Chase A, Iqbal A, Pocock F, Kaeda J, Cwynarski K, Goldman JM, Cross NCP (2000) Fusion of H4/D10S170 to the platelet-derived growth factor receptor β in BCR-ABL-negative myeloproliferative disorders with a t(5;10)(q33;q21). Cancer Res 60:3592–3598PubMed
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Zurück zum Zitat Garcia JL, FontdeMora J, Hernandez JM, Queizan JA, Gutierrez NC, Hernandez JM San Miguel JF (2003) imatinib mesylat elicts positive clinical response in atypical chronic myeloid leukaemia involving the platelet-derived growth factor receptor beta. Blood 102:2699–2700PubMedCrossRef Garcia JL, FontdeMora J, Hernandez JM, Queizan JA, Gutierrez NC, Hernandez JM San Miguel JF (2003) imatinib mesylat elicts positive clinical response in atypical chronic myeloid leukaemia involving the platelet-derived growth factor receptor beta. Blood 102:2699–2700PubMedCrossRef
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Zurück zum Zitat Bastie J-N, Garcia I, Terré C, Cross NCP, Mahon F-X, Castaigne S (2004) Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor β-gene. Haematologica 89:1263–1264PubMed Bastie J-N, Garcia I, Terré C, Cross NCP, Mahon F-X, Castaigne S (2004) Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor β-gene. Haematologica 89:1263–1264PubMed
Metadaten
Titel
Fusion of H4/D10S170 to PDGFRβ in a patient with chronic myelomonocytic leukemia and long-term responsiveness to imatinib
verfasst von
Matthias Drechsler
Barbara Hildebrandt
Andrea Kündgen
Ulrich Germing
Brigitte Royer-Pokora
Publikationsdatum
01.05.2007
Verlag
Springer-Verlag
Erschienen in
Annals of Hematology / Ausgabe 5/2007
Print ISSN: 0939-5555
Elektronische ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-006-0247-5

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