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Co-expression of two FAB-specific chromosome changes, t(15; 17) and t(8; 21), in a case of acute promyelocytic leukemia

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Abstract

 We describe a case of acute promyelocytic leukemia ANLL-M3 with association of t(15; 17) and t(8; 21) and various chromosomal aberrations. Clinically, immunologically, and morphologically, our patient fits the diagnosis of typical ANLL-M3. The co-existence of two specific FAB chromosomal translocations in a single leukemic clone is rare. The rarity of this association enhances the significance of this report.

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Authors and Affiliations

  1. Department of Hematology, Block-A, Research, Postgraduate Institute of Medical Education and Research, Chandigarh – 160012, India, , , , , , IN

    A. Movafagh & N. Varma

  2. Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh – 160012, India, , , , , , IN

    S. Varma

Authors
  1. A. Movafagh
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  2. N. Varma
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  3. S. Varma
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Received: 27 September 1995 / Accepted 13 March 1996

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Movafagh, A., Varma, N. & Varma, S. Co-expression of two FAB-specific chromosome changes, t(15; 17) and t(8; 21), in a case of acute promyelocytic leukemia. Ann Hematol 72, 375–377 (1996). https://doi.org/10.1007/s002770050189

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  • DOI: https://doi.org/10.1007/s002770050189

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