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01.09.2008 | Case Report

A case of AA amyloidosis associated with rheumatoid arthritis effectively treated with Infliximab

verfasst von: Takeshi Kuroda, Yasuhiro Otaki, Hiroe Sato, Takeo Fujimura, Takeshi Nakatsue, Syuichi Murakami, Minoru Sakatsume, Masaaki Nakano, Fumitake Gejyo

Erschienen in: Rheumatology International | Ausgabe 11/2008

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Abstract

We report the case of a 55-year-old Japanese woman with reactive AA amyloidosis associated with rheumatoid arthritis, in which inflammatory disease was completely suppressed with infliximab. Nephrotic syndrome was observed and renal biopsy specimens revealed amyloidosis deposits. Treatment with infliximab normalized the serum amyloid A (SAA) protein level, and subsequently nephritic syndrome disappeared and her creatinine clearance improved. Serial gastrointestinal biopsy specimens showed marked lasting regression of amyloid deposits. Thus treatment with infliximab represents an important therapeutic strategy for AA amyloidosis associated with RA.

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Titel: A case of AA amyloidosis associated with rheumatoid arthritis effectively treated with Infliximab
verfasst von: Takeshi Kuroda
Yasuhiro Otaki
Hiroe Sato
Takeo Fujimura
Takeshi Nakatsue
Syuichi Murakami
Minoru Sakatsume
Masaaki Nakano
Fumitake Gejyo
Publikationsdatum: 01.09.2008
Verlag: Springer-Verlag
Erschienen in: Rheumatology International / Ausgabe 11/2008
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-008-0590-z

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