Skip to main content
Erschienen in: Rheumatology International 5/2010

01.03.2010 | Case Report

Infliximab for reactive arthritis secondary to Chlamydia trachomatis infection

verfasst von: Marcelo Derbli Schafranski

Erschienen in: Rheumatology International | Ausgabe 5/2010

Einloggen, um Zugang zu erhalten

Abstract

Reactive arthritis is an autoimmune disease that develops 2–4 weeks after a triggering infection, resulting mainly in synovitis/enthesitis of the lower limbs, but with a wide array of possible extra-articular manifestations. Most of the cases are self-limited, lasting some weeks to months, and respond well to nonsteroidal anti-inflammatory drugs (NSAIDs), but a considerable number of cases (about 20%) run a chronic disabling course, requiring immunosuppressants (methotrexate, sulphasalazine) to adequate control of the inflammatory symptoms. We describe, for the first time to our knowledge, a case of a Chlamydia trachomatis-related reactive arthritis refractory to methotrexate and sulphasalazine that was successfully treated with the monoclonal antibody anti-TNF-alpha and infliximab.
Literatur
3.
Zurück zum Zitat Furst DE, Breedveld FC, Kalden JR et al (2007) Updated consensus statement on biological agents for the treatment of rheumatic diseases. Ann Rheum Dis 66(suppl 3):2–22 Furst DE, Breedveld FC, Kalden JR et al (2007) Updated consensus statement on biological agents for the treatment of rheumatic diseases. Ann Rheum Dis 66(suppl 3):2–22
5.
Zurück zum Zitat Butrimiene I, Jarmalaite S, Ranceva J, Venalis A, Jasiuleviciute L, Zvirbliene (2004) A Different cytokine profiles in patients with chronic and acute reactive arthritis. Rheumatology (Oxford) 43(10):1300–1304. doi:10.1093/rheumatology/keh323 Butrimiene I, Jarmalaite S, Ranceva J, Venalis A, Jasiuleviciute L, Zvirbliene (2004) A Different cytokine profiles in patients with chronic and acute reactive arthritis. Rheumatology (Oxford) 43(10):1300–1304. doi:10.​1093/​rheumatology/​keh323
7.
Zurück zum Zitat Lange U, Teichmann J, Stracke H (2000) Correlation between plasma TNF-alpha, IGF-1, biochemical markers of bone metabolism, markers of inflammation/disease activity, and clinical manifestations in ankylosing spondylitis. Eur J Med Res 5:507–511PubMed Lange U, Teichmann J, Stracke H (2000) Correlation between plasma TNF-alpha, IGF-1, biochemical markers of bone metabolism, markers of inflammation/disease activity, and clinical manifestations in ankylosing spondylitis. Eur J Med Res 5:507–511PubMed
Metadaten
Titel
Infliximab for reactive arthritis secondary to Chlamydia trachomatis infection
verfasst von
Marcelo Derbli Schafranski
Publikationsdatum
01.03.2010
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 5/2010
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-009-0965-9

Weitere Artikel der Ausgabe 5/2010

Rheumatology International 5/2010 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.