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Erschienen in: Rheumatology International 2/2013

01.02.2013 | Original Article

Rheumatoid arthritis prevalence, incidence, and mortality rates: a nationwide population study in Taiwan

verfasst von: Chang-Fu Kuo, Shue-Fen Luo, Lai-Chu See, I-Jun Chou, Hsiao-Chun Chang, Kuang-Hui Yu

Erschienen in: Rheumatology International | Ausgabe 2/2013

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Abstract

There are few nationwide population studies on the epidemiology of rheumatoid arthritis (RA). Here, we present the epidemiologic features and mortality rates of RA in Taiwan. The catastrophic illness registry of the Taiwan National Health Insurance Research Database and the National Death Registry of Taiwan were used to estimate the incidence and prevalence of RA and its associated mortality rates. All-cause and cause-specific standardized mortality ratios (SMRs) were calculated and compared to the corresponding ratios of the general population in 2002. The study comprised 15,967 incident RA cases (3,562 men; 12,405 women) occurring from 2002 through 2007. The annual incidence of RA was 15.8 cases (men, 10.1; women, 41.0) per 100,000 population. The period prevalence was 97.5 cases (men, 37.4; women, 159.5) per 100,000 population. During 67,010 person-years of follow-up, 985 deaths (372 men; 613 women) were identified, and this corresponded to a crude mortality rate of 14.7 deaths (men, 25.0; women, 11.8) per 1,000 person-years. Compared to female patients, male patients had a higher risk for mortality (log-rank test, p < 0.001). RA patients had an SMR of 1.25 (95 % confidence interval [CI], 1.18–1.33) for all-cause mortality. Compared to the general population, RA patients of both genders in this cohort had a significantly higher risk of mortality from infection (SMR, 2.49) and gastrointestinal diseases (SMR, 1.76). RA incidence and prevalence were higher in women than in men. Mortality was higher in men than in women. Compared to the general population, RA patients had a higher risk of death, particularly from infection and gastrointestinal diseases.
Literatur
1.
Zurück zum Zitat Young A, Koduri G (2007) Extra-articular manifestations and complications of rheumatoid arthritis. Best Pract Res Clin Rheumatol 21(5):907–927PubMedCrossRef Young A, Koduri G (2007) Extra-articular manifestations and complications of rheumatoid arthritis. Best Pract Res Clin Rheumatol 21(5):907–927PubMedCrossRef
2.
Zurück zum Zitat Chou CT, Pei L, Chang DM, Lee CF, Schumacher HR, Liang MH (1994) Prevalence of rheumatic diseases in Taiwan: a population study of urban, suburban, rural differences. J Rheumatol 21(2):302–306PubMed Chou CT, Pei L, Chang DM, Lee CF, Schumacher HR, Liang MH (1994) Prevalence of rheumatic diseases in Taiwan: a population study of urban, suburban, rural differences. J Rheumatol 21(2):302–306PubMed
3.
Zurück zum Zitat Sokka T, Abelson B, Pincus T (2008) Mortality in rheumatoid arthritis: 2008 update. Clin Exp Rheumatol 26(5 Suppl 51):S35–S61PubMed Sokka T, Abelson B, Pincus T (2008) Mortality in rheumatoid arthritis: 2008 update. Clin Exp Rheumatol 26(5 Suppl 51):S35–S61PubMed
4.
Zurück zum Zitat Hakoda M, Oiwa H, Kasagi F, Masunari N, Yamada M, Suzuki G, Fujiwara S (2005) Mortality of rheumatoid arthritis in Japan: a longitudinal cohort study. Ann Rheum Dis 64(10):1451–1455PubMedCrossRef Hakoda M, Oiwa H, Kasagi F, Masunari N, Yamada M, Suzuki G, Fujiwara S (2005) Mortality of rheumatoid arthritis in Japan: a longitudinal cohort study. Ann Rheum Dis 64(10):1451–1455PubMedCrossRef
5.
Zurück zum Zitat Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31(3):315–324PubMedCrossRef Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31(3):315–324PubMedCrossRef
6.
Zurück zum Zitat Lu TH, Shau WY, Shih TP, Lee MC, Chou MC, Lin CK (2001) Factors associated with errors in death certificate completion. A national study in Taiwan. J Clin Epidemiol 54(3):232–238PubMedCrossRef Lu TH, Shau WY, Shih TP, Lee MC, Chou MC, Lin CK (2001) Factors associated with errors in death certificate completion. A national study in Taiwan. J Clin Epidemiol 54(3):232–238PubMedCrossRef
7.
Zurück zum Zitat Lu TH, Lee MC, Chou MC (2000) Accuracy of cause-of-death coding in Taiwan: types of miscoding and effects on mortality statistics. Int J Epidemiol 29(2):336–343PubMedCrossRef Lu TH, Lee MC, Chou MC (2000) Accuracy of cause-of-death coding in Taiwan: types of miscoding and effects on mortality statistics. Int J Epidemiol 29(2):336–343PubMedCrossRef
8.
Zurück zum Zitat Ulm K (1990) A simple method to calculate the confidence interval of a standardized mortality ratio (SMR). Am J Epidemiol 131(2):373–375PubMed Ulm K (1990) A simple method to calculate the confidence interval of a standardized mortality ratio (SMR). Am J Epidemiol 131(2):373–375PubMed
9.
Zurück zum Zitat Shichikawa K, Inoue K, Hirota S, Maeda A, Ota H, Kimura M, Ushiyama T, Tsujimoto M (1999) Changes in the incidence and prevalence of rheumatoid arthritis in Kamitonda, Wakayama, Japan, 1965–1996. Ann Rheum Dis 58(12):751–756PubMedCrossRef Shichikawa K, Inoue K, Hirota S, Maeda A, Ota H, Kimura M, Ushiyama T, Tsujimoto M (1999) Changes in the incidence and prevalence of rheumatoid arthritis in Kamitonda, Wakayama, Japan, 1965–1996. Ann Rheum Dis 58(12):751–756PubMedCrossRef
10.
Zurück zum Zitat Kato H, Duff IF, Russell WJ, Uda Y, Hamilton HB, Kawamoto S, Johnson KG (1971) Rheumatoid arthritis and gout in Hiroshima and Nagasaki, Japan. A prevalence and incidence study. J Chronic Dis 23(9):659–679PubMedCrossRef Kato H, Duff IF, Russell WJ, Uda Y, Hamilton HB, Kawamoto S, Johnson KG (1971) Rheumatoid arthritis and gout in Hiroshima and Nagasaki, Japan. A prevalence and incidence study. J Chronic Dis 23(9):659–679PubMedCrossRef
11.
Zurück zum Zitat Wood JW, Kato H, Johnson KG, Uda Y, Russell WJ, Duff IF (1967) Rheumatoid arthritis in Hiroshima and Nagasaki, Japan. Prevalence, incidence, and clinical characteristics. Arthritis Rheum 10(1):21–31PubMedCrossRef Wood JW, Kato H, Johnson KG, Uda Y, Russell WJ, Duff IF (1967) Rheumatoid arthritis in Hiroshima and Nagasaki, Japan. Prevalence, incidence, and clinical characteristics. Arthritis Rheum 10(1):21–31PubMedCrossRef
12.
Zurück zum Zitat Riise T, Jacobsen BK, Gran JT (2000) Incidence and prevalence of rheumatoid arthritis in the county of Troms, northern Norway. J Rheumatol 27(6):1386–1389PubMed Riise T, Jacobsen BK, Gran JT (2000) Incidence and prevalence of rheumatoid arthritis in the county of Troms, northern Norway. J Rheumatol 27(6):1386–1389PubMed
13.
Zurück zum Zitat Soderlin MK, Borjesson O, Kautiainen H, Skogh T, Leirisalo-Repo M (2002) Annual incidence of inflammatory joint diseases in a population based study in southern Sweden. Ann Rheum Dis 61(10):911–915PubMedCrossRef Soderlin MK, Borjesson O, Kautiainen H, Skogh T, Leirisalo-Repo M (2002) Annual incidence of inflammatory joint diseases in a population based study in southern Sweden. Ann Rheum Dis 61(10):911–915PubMedCrossRef
14.
Zurück zum Zitat Uhlig T, Kvien TK, Glennas A, Smedstad LM, Forre O (1998) The incidence and severity of rheumatoid arthritis, results from a county register in Oslo, Norway. J Rheumatol 25(6):1078–1084PubMed Uhlig T, Kvien TK, Glennas A, Smedstad LM, Forre O (1998) The incidence and severity of rheumatoid arthritis, results from a county register in Oslo, Norway. J Rheumatol 25(6):1078–1084PubMed
15.
Zurück zum Zitat Kaipiainen-Seppanen O, Aho K, Nikkarinen M (2001) Regional differences in the incidence of rheumatoid arthritis in Finland in 1995. Ann Rheum Dis 60(2):128–132PubMedCrossRef Kaipiainen-Seppanen O, Aho K, Nikkarinen M (2001) Regional differences in the incidence of rheumatoid arthritis in Finland in 1995. Ann Rheum Dis 60(2):128–132PubMedCrossRef
16.
Zurück zum Zitat Zeng QY, Chen R, Darmawan J, Xiao ZY, Chen SB, Wigley R, Le Chen S, Zhang NZ (2008) Rheumatic diseases in China. Arthritis Res Ther 10(1):R17PubMedCrossRef Zeng QY, Chen R, Darmawan J, Xiao ZY, Chen SB, Wigley R, Le Chen S, Zhang NZ (2008) Rheumatic diseases in China. Arthritis Res Ther 10(1):R17PubMedCrossRef
17.
Zurück zum Zitat Cobb S (1963) The epidemiology of rheumatoid arthritis. Bull Acad Med N J 9:52–60PubMed Cobb S (1963) The epidemiology of rheumatoid arthritis. Bull Acad Med N J 9:52–60PubMed
18.
Zurück zum Zitat Gabriel SE (2008) Cardiovascular morbidity and mortality in rheumatoid arthritis. Am J Med 121(10 Suppl 1):S9–S14PubMedCrossRef Gabriel SE (2008) Cardiovascular morbidity and mortality in rheumatoid arthritis. Am J Med 121(10 Suppl 1):S9–S14PubMedCrossRef
19.
Zurück zum Zitat Solomon DH, Karlson EW, Rimm EB, Cannuscio CC, Mandl LA, Manson JE, Stampfer MJ, Curhan GC (2003) Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation 107(9):1303–1307PubMedCrossRef Solomon DH, Karlson EW, Rimm EB, Cannuscio CC, Mandl LA, Manson JE, Stampfer MJ, Curhan GC (2003) Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation 107(9):1303–1307PubMedCrossRef
20.
Zurück zum Zitat Meune C, Touze E, Trinquart L, Allanore Y (2009) Trends in cardiovascular mortality in patients with rheumatoid arthritis over 50 years: a systematic review and meta-analysis of cohort studies. Rheumatology (Oxford) 48(10):1309–1313CrossRef Meune C, Touze E, Trinquart L, Allanore Y (2009) Trends in cardiovascular mortality in patients with rheumatoid arthritis over 50 years: a systematic review and meta-analysis of cohort studies. Rheumatology (Oxford) 48(10):1309–1313CrossRef
21.
Zurück zum Zitat Doran MF, Crowson CS, Pond GR, O’Fallon WM, Gabriel SE (2002) Frequency of infection in patients with rheumatoid arthritis compared with controls: a population-based study. Arthritis Rheum 46(9):2287–2293PubMedCrossRef Doran MF, Crowson CS, Pond GR, O’Fallon WM, Gabriel SE (2002) Frequency of infection in patients with rheumatoid arthritis compared with controls: a population-based study. Arthritis Rheum 46(9):2287–2293PubMedCrossRef
22.
Zurück zum Zitat Symmons DP, Jones MA, Scott DL, Prior P (1998) Longterm mortality outcome in patients with rheumatoid arthritis: early presenters continue to do well. J Rheumatol 25(6):1072–1077PubMed Symmons DP, Jones MA, Scott DL, Prior P (1998) Longterm mortality outcome in patients with rheumatoid arthritis: early presenters continue to do well. J Rheumatol 25(6):1072–1077PubMed
23.
Zurück zum Zitat Wolfe F, Mitchell DM, Sibley JT, Fries JF, Bloch DA, Williams CA, Spitz PW, Haga M, Kleinheksel SM, Cathey MA (1994) The mortality of rheumatoid arthritis. Arthritis Rheum 37(4):481–494PubMedCrossRef Wolfe F, Mitchell DM, Sibley JT, Fries JF, Bloch DA, Williams CA, Spitz PW, Haga M, Kleinheksel SM, Cathey MA (1994) The mortality of rheumatoid arthritis. Arthritis Rheum 37(4):481–494PubMedCrossRef
24.
Zurück zum Zitat Doran MF, Crowson CS, Pond GR, O’Fallon WM, Gabriel SE (2002) Predictors of infection in rheumatoid arthritis. Arthritis Rheum 46(9):2294–2300PubMedCrossRef Doran MF, Crowson CS, Pond GR, O’Fallon WM, Gabriel SE (2002) Predictors of infection in rheumatoid arthritis. Arthritis Rheum 46(9):2294–2300PubMedCrossRef
Metadaten
Titel
Rheumatoid arthritis prevalence, incidence, and mortality rates: a nationwide population study in Taiwan
verfasst von
Chang-Fu Kuo
Shue-Fen Luo
Lai-Chu See
I-Jun Chou
Hsiao-Chun Chang
Kuang-Hui Yu
Publikationsdatum
01.02.2013
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 2/2013
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-012-2411-7

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