Erschienen in:
01.03.2014 | Letter to the Editors
Systemic lupus erythematosus activity and depression
verfasst von:
Thelma Skare, Vinicius D. da Silva Magalhães, Ramón E. Siqueira
Erschienen in:
Rheumatology International
|
Ausgabe 3/2014
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Excerpt
Depression is common in patients with chronic diseases. This also happens in patients with systemic lupus erythematosus (SLE) [
1]. Although the causal elements are not fully known, it is assumed that some contributing factors are the physical disability generated by joint pains and fatigue, concerns about disease prognosis and a negative body image caused by skin lesions and glucocorticoid use [
2]. However, it is possible that lupus activity on central nervous system also could be associated with mood disorders [
3]. Even though only seizures and psychosis are part of the classification criteria of the American College of Rheumatology for the diagnosis of this disease [
4], major depression is considered one of the neuropsychiatric manifestations of SLE [
3]. Milder forms are usually interpreted as associated disorders [
3]. Depression in SLE is not formally assessed in daily practice and is frequently underdiagnosed. …