Skip to main content
Erschienen in: European Radiology 12/2008

01.12.2008 | Cardiac

Characterisation of peripartum cardiomyopathy by cardiac magnetic resonance imaging

verfasst von: Frederic Mouquet, Christophe Lions, Pascal de Groote, Nadia Bouabdallaoui, Serge Willoteaux, Joel Dagorn, Philippe Deruelle, Nicolas Lamblin, Christophe Bauters, Jean Paul Beregi

Erschienen in: European Radiology | Ausgabe 12/2008

Einloggen, um Zugang zu erhalten

Abstract

Peripartum cardiomyopathy (PPCM) is a rare cause of heart failure. Only half of the patients recover normal cardiac function. We assessed the usefulness of magnetic resonance imaging (MRI) and late enhancement imaging to detect myocardial fibrosis in order to predict cardiac function recovery in patients with peripartum cardiomyopathy. Among a consecutive series of 1,037 patients referred for heart failure treatment or prognostic evaluation between 1999 and 2006, eight women had confirmed PPCM. They all underwent echocardiography and cardiac MRI for assessment of left ventricular anatomy, systolic function and detection of myocardial fibrosis through late enhancement imaging. Mean (± SD) baseline left ventricular ejection fraction (LVEF) was 28 ± 4%. After a follow-up of 50 ± 9 months, half the patients recovered normal cardiac function (LVEF = 58 ± 4%) and four did not (LVEF = 35 ± 6%). None of the eight patients exhibited abnormal myocardial late enhancement. No difference in MRI characteristics was observed between the two groups. Patients with PPCM do not exhibit a specific cardiac MRI pattern and particularly no myocardial late enhancement. It suggests that myocardial fibrosis does not play a major role in the limitation of cardiac function recovery after PPCM.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Fett JD, Christie LG, Carraway RD, Murphy JG (2005) Five-year prospective study of the incidence and prognosis of peripartum cardiomyopathy at a single institution. Mayo Clin Proc 80:1602–1606PubMedCrossRef Fett JD, Christie LG, Carraway RD, Murphy JG (2005) Five-year prospective study of the incidence and prognosis of peripartum cardiomyopathy at a single institution. Mayo Clin Proc 80:1602–1606PubMedCrossRef
2.
Zurück zum Zitat Pearson GD, Veille JC, Rahimtoola S, Hsia J, Oakley CM, Hosenpud JD, Ansari A, Baughman KL (2000) Peripartum cardiomyopathy: National Heart, Lung, and Blood Institute and Office of Rare Diseases (National Institutes of Health) workshop recommendations and review. Jama 283:1183–1188PubMedCrossRef Pearson GD, Veille JC, Rahimtoola S, Hsia J, Oakley CM, Hosenpud JD, Ansari A, Baughman KL (2000) Peripartum cardiomyopathy: National Heart, Lung, and Blood Institute and Office of Rare Diseases (National Institutes of Health) workshop recommendations and review. Jama 283:1183–1188PubMedCrossRef
3.
Zurück zum Zitat Lamparter S, Pankuweit S, Maisch B (2007) Clinical and immunologic characteristics in peripartum cardiomyopathy. Int J Cardiol 118:14–20PubMedCrossRef Lamparter S, Pankuweit S, Maisch B (2007) Clinical and immunologic characteristics in peripartum cardiomyopathy. Int J Cardiol 118:14–20PubMedCrossRef
4.
Zurück zum Zitat Elkayam U, Akhter MW, Singh H, Khan S, Bitar F, Hameed A, Shotan A (2005) Pregnancy-associated cardiomyopathy: clinical characteristics and a comparison between early and late presentation. Circulation 111:2050–2055PubMedCrossRef Elkayam U, Akhter MW, Singh H, Khan S, Bitar F, Hameed A, Shotan A (2005) Pregnancy-associated cardiomyopathy: clinical characteristics and a comparison between early and late presentation. Circulation 111:2050–2055PubMedCrossRef
5.
Zurück zum Zitat Sutton MS, Cole P, Plappert M, Saltzman D, Goldhaber S (1991) Effects of subsequent pregnancy on left ventricular function in peripartum cardiomyopathy. Am Heart J 121:1776–1778PubMedCrossRef Sutton MS, Cole P, Plappert M, Saltzman D, Goldhaber S (1991) Effects of subsequent pregnancy on left ventricular function in peripartum cardiomyopathy. Am Heart J 121:1776–1778PubMedCrossRef
6.
Zurück zum Zitat Melvin KR, Richardson PJ, Olsen EG, Daly K, Jackson G (1982) Peripartum cardiomyopathy due to myocarditis. N Engl J Med 307:731–734PubMed Melvin KR, Richardson PJ, Olsen EG, Daly K, Jackson G (1982) Peripartum cardiomyopathy due to myocarditis. N Engl J Med 307:731–734PubMed
7.
Zurück zum Zitat Midei MG, DeMent SH, Feldman AM, Hutchins GM, Baughman KL (1990) Peripartum myocarditis and cardiomyopathy. Circulation 81:922–928PubMed Midei MG, DeMent SH, Feldman AM, Hutchins GM, Baughman KL (1990) Peripartum myocarditis and cardiomyopathy. Circulation 81:922–928PubMed
8.
Zurück zum Zitat Rizeq MN, Rickenbacher PR, Fowler MB, Billingham ME (1994) Incidence of myocarditis in peripartum cardiomyopathy. Am J Cardiol 74:474–477PubMedCrossRef Rizeq MN, Rickenbacher PR, Fowler MB, Billingham ME (1994) Incidence of myocarditis in peripartum cardiomyopathy. Am J Cardiol 74:474–477PubMedCrossRef
9.
Zurück zum Zitat Demakis JG, Rahimtoola SH (1971) Peripartum cardiomyopathy. Circulation 44:964–968PubMed Demakis JG, Rahimtoola SH (1971) Peripartum cardiomyopathy. Circulation 44:964–968PubMed
11.
Zurück zum Zitat Pennell DJ, Sechtem UP, Higgins CB, Manning WJ, Pohost GM, Rademakers FE, van Rossum AC, Shaw LJ, Yucel EK (2004) Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. Eur Heart J 25:1940–1965PubMedCrossRef Pennell DJ, Sechtem UP, Higgins CB, Manning WJ, Pohost GM, Rademakers FE, van Rossum AC, Shaw LJ, Yucel EK (2004) Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. Eur Heart J 25:1940–1965PubMedCrossRef
12.
Zurück zum Zitat Mahrholdt H, Wagner A, Judd RM, Sechtem U, Kim RJ (2005) Delayed enhancement cardiovascular magnetic resonance assessment of non-ischaemic cardiomyopathies. Eur Heart J 26:1461–1474PubMedCrossRef Mahrholdt H, Wagner A, Judd RM, Sechtem U, Kim RJ (2005) Delayed enhancement cardiovascular magnetic resonance assessment of non-ischaemic cardiomyopathies. Eur Heart J 26:1461–1474PubMedCrossRef
13.
Zurück zum Zitat Park S, Choi BW, Rim SJ, Shim CY, Ko YG, Kang SM, Ha JW, Jang Y, Chung N, Choe KO, Cho SY (2006) Delayed hyperenhancement magnetic resonance imaging is useful in predicting functional recovery of nonischemic left ventricular systolic dysfunction. J Card Fail 12:93–99PubMedCrossRef Park S, Choi BW, Rim SJ, Shim CY, Ko YG, Kang SM, Ha JW, Jang Y, Chung N, Choe KO, Cho SY (2006) Delayed hyperenhancement magnetic resonance imaging is useful in predicting functional recovery of nonischemic left ventricular systolic dysfunction. J Card Fail 12:93–99PubMedCrossRef
14.
Zurück zum Zitat Assomull RG, Prasad SK, Lyne J, Smith G, Burman ED, Khan M, Sheppard MN, Poole-Wilson PA, Pennell DJ (2006) Cardiovascular magnetic resonance, fibrosis, and prognosis in dilated cardiomyopathy. J Am Coll Cardiol 48:1977–1985PubMedCrossRef Assomull RG, Prasad SK, Lyne J, Smith G, Burman ED, Khan M, Sheppard MN, Poole-Wilson PA, Pennell DJ (2006) Cardiovascular magnetic resonance, fibrosis, and prognosis in dilated cardiomyopathy. J Am Coll Cardiol 48:1977–1985PubMedCrossRef
15.
Zurück zum Zitat Kaandorp TA, Lamb HJ, Bax JJ, Boersma E, Viergever EP, van der Wall EE, de Roos A (2005) Prediction of beneficial effect of beta blocker treatment in severe ischaemic cardiomyopathy: assessment of global left ventricular ejection fraction using dobutamine stress cardiovascular magnetic resonance. Heart 91:1471–1472PubMedCrossRef Kaandorp TA, Lamb HJ, Bax JJ, Boersma E, Viergever EP, van der Wall EE, de Roos A (2005) Prediction of beneficial effect of beta blocker treatment in severe ischaemic cardiomyopathy: assessment of global left ventricular ejection fraction using dobutamine stress cardiovascular magnetic resonance. Heart 91:1471–1472PubMedCrossRef
16.
Zurück zum Zitat McCrohon JA, Moon JC, Prasad SK, McKenna WJ, Lorenz CH, Coats AJ, Pennell DJ (2003) Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance. Circulation 108:54–59PubMedCrossRef McCrohon JA, Moon JC, Prasad SK, McKenna WJ, Lorenz CH, Coats AJ, Pennell DJ (2003) Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance. Circulation 108:54–59PubMedCrossRef
17.
Zurück zum Zitat Messroghli DR, Radjenovic A, Kozerke S, Higgins DM, Sivananthan MU, Ridgway JP (2004) Modified Look-Locker inversion recovery (MOLLI) for high-resolution T1 mapping of the heart. Magn Reson Med 52:141–146PubMedCrossRef Messroghli DR, Radjenovic A, Kozerke S, Higgins DM, Sivananthan MU, Ridgway JP (2004) Modified Look-Locker inversion recovery (MOLLI) for high-resolution T1 mapping of the heart. Magn Reson Med 52:141–146PubMedCrossRef
18.
Zurück zum Zitat Gissler M, Deneux-Tharaux C, Alexander S, Berg CJ, Bouvier-Colle MH, Harper M, Nannini A, Breart G, Buekens P (2007) Pregnancy-related deaths in four regions of Europe and the United States in 1999–2000: characterisation of unreported deaths. Eur J Obstet Gynecol Reprod Biol 133:179–185PubMedCrossRef Gissler M, Deneux-Tharaux C, Alexander S, Berg CJ, Bouvier-Colle MH, Harper M, Nannini A, Breart G, Buekens P (2007) Pregnancy-related deaths in four regions of Europe and the United States in 1999–2000: characterisation of unreported deaths. Eur J Obstet Gynecol Reprod Biol 133:179–185PubMedCrossRef
19.
Zurück zum Zitat Ferriere M, Sacrez A, Bouhour JB, Cassagnes J, Geslin P, Dubourg O, Komajda M, Degeorges M (1990) Cardiomyopathy in the peripartum period: current aspects. A multicenter study. Arch Mal Coeur Vaiss 83:1563–1569PubMed Ferriere M, Sacrez A, Bouhour JB, Cassagnes J, Geslin P, Dubourg O, Komajda M, Degeorges M (1990) Cardiomyopathy in the peripartum period: current aspects. A multicenter study. Arch Mal Coeur Vaiss 83:1563–1569PubMed
20.
Zurück zum Zitat Kawano H, Tsuneto A, Koide Y, Tasaki H, Sueyoshi E, Sakamoto I, Hayashi T (2008) Magnetic resonance imaging in a patient with peripartum cardiomyopathy. Intern Med 47:97–102PubMedCrossRef Kawano H, Tsuneto A, Koide Y, Tasaki H, Sueyoshi E, Sakamoto I, Hayashi T (2008) Magnetic resonance imaging in a patient with peripartum cardiomyopathy. Intern Med 47:97–102PubMedCrossRef
Metadaten
Titel
Characterisation of peripartum cardiomyopathy by cardiac magnetic resonance imaging
verfasst von
Frederic Mouquet
Christophe Lions
Pascal de Groote
Nadia Bouabdallaoui
Serge Willoteaux
Joel Dagorn
Philippe Deruelle
Nicolas Lamblin
Christophe Bauters
Jean Paul Beregi
Publikationsdatum
01.12.2008
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 12/2008
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-008-1067-x

Weitere Artikel der Ausgabe 12/2008

European Radiology 12/2008 Zur Ausgabe

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.