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Erschienen in: European Radiology 10/2010

01.10.2010 | Ultrasound

Contrast-enhanced ultrasound in the staging of acute pancreatitis

verfasst von: Tomás Ripollés, María J Martínez, Estela López, Inmaculada Castelló, Fructuoso Delgado

Erschienen in: European Radiology | Ausgabe 10/2010

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Abstract

Objective

To determine the diagnostic value of contrast-enhanced ultrasound (CEUS) in the assessment of acute pancreatitis, with computed tomography (CT) as the reference standard.

Methods

Fifty consecutive patients (mean age 58.4 years; range 23–86 years) with acute pancreatitis underwent prospectively both CT and ultrasonography, including CEUS, within a 24-h interval. Pancreatic vascularisation was evaluated with CEUS after injection of a second-generation US contrast-enhancing agent. Acute pancreatitis severity was graded according to the Balthazar index. The results were compared with CT severity index and clinical outcome by using Spearman’s correlation coefficient.

Results

A significant correlation between CT and CEUS was found for the CT severity index (r = 0.926), extent of necrosis (r = 0.893) and Balthazar grade (r = 0.884). The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for detecting severe acute pancreatitis based on CT findings (severity index greater than 3 and/or presence of necrosis) were respectively 91%, 100%, 100% and 83%. A significant correlation between CEUS severity index and clinical variables was found: Ranson score (r = 0.442), C-reactive protein (CRP) levels 48 h after admission (r = 0.385) and length of hospital stay (r = 0.362).

Conclusion

CEUS is comparable to CT in detecting pancreatic necrosis as well as predicting its clinical course. Therefore, when CT is contraindicated CEUS may be a valid alternative.
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Metadaten
Titel
Contrast-enhanced ultrasound in the staging of acute pancreatitis
verfasst von
Tomás Ripollés
María J Martínez
Estela López
Inmaculada Castelló
Fructuoso Delgado
Publikationsdatum
01.10.2010
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 10/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1824-5

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