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01.11.2010 | Interventional

Laser-induced thermotherapy (LITT)—evaluation of a miniaturised applicator and implementation in a 1.0-T high-field open MRI applying a porcine liver model

verfasst von: Florian Streitparth, Gesine Knobloch, Dirk Balmert, Sascha Chopra, J. Rump, Uta Wonneberger, Carsten Philipp, Bernd Hamm, Ulf Teichgräber

Erschienen in: European Radiology | Ausgabe 11/2010

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Abstract

Objective:

To evaluate the feasibility and safety of a novel LITT applicator for thermal ablation of liver malignancies in 1.0-T high-field open MRI.

Methods:

A miniaturised 6-F double-tubed protective catheter with a closed cooling circuit was used with a flexible laser fibre, connected to a 1,064-nm Nd:YAG laser and evaluated in non-perfused porcine livers (18–30 W for 10–20 min, 2-W and 2-min increments; n = 210/applicator) in reference to an established 9-F system. As a proof of concept, MR-guided LITT was performed in two healthy domestic pigs in high-field open MRI.

Results:

Ex-vivo, the coagulation volumes induced by the 6-F system with maximum applicable power of 24 W for 20 min (33.0 ± 4.4 cm³) did not differ significantly from those set with the 9-F system at 30 W for 20 min (35.8 ± 4.9 cm³) (p = 0.73). A flow-rate of 15 ml/min of the cooling saline solution was sufficient. MR navigation and thermometry were feasible.

Conclusion:

The miniaturised 6-F applicator can create comparable coagulation sizes to those of the 9-F system. Applicator guidance and online-thermometry in high-field open MRI are feasible.

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Vogl TJ, Straub R, Eichler K, Woitaschek D, Mack MG (2002) Malignant liver tumors treated with MR imaging-guided laser-induced thermotherapy: experience with complications in 899 patients (2, 520 lesions). Radiology 225:367–377CrossRefPubMed

Fiedler VU, Schwarzmaier HJ, Eickmeyer F, Muller FP, Schoepp C, Verreet PR (2001) Laser-induced interstitial thermotherapy of liver metastases in an interventional 0.5 Tesla MRI system: technique and first clinical experiences. J Magn Reson Imaging 13:729–737CrossRefPubMed

Vogl TJ, Mack MG, Roggan A et al (1998) Internally cooled power laser for MR-guided interstitial laser-induced thermotherapy of liver lesions: initial clinical results. Radiology 209:381–385PubMed

Wacker FK, Reither K, Ritz JP, Roggan A, Germer CT, Wolf KJ (2001) MR-guided interstitial laser-induced thermotherapy of hepatic metastasis combined with arterial blood flow reduction: technique and first clinical results in an open MR system. J Magn Reson Imaging 13:31–36CrossRefPubMed

Schmitz-Rode T (2003) Miniaturization and related trends in technology: not applicable for radiology? Rofo 175:152–155PubMed

Hosten N, Stier A, Weigel C et al (2003) Laser-induced thermotherapy (LITT) of lung metastases: description of a miniaturized applicator, optimization, and initial treatment of patients. Rofo 175:393–400PubMed

Puls R, Stroszczynski C, Gaffke G, Hosten N, Felix R, Speck U (2003) Laser-induced thermotherapy (LITT) of liver metastases: MR-guided percutaneous insertion of an MRI-compatible irrigated microcatheter system using a closed high-field unit. J Magn Reson Imaging 17:663–670CrossRefPubMed

Meister D, Hubner F, Mack M, Vogl TJ (2007) MR thermometry for laser-induced thermotherapy at 1.5 Tesla. Rofo 179:497–505PubMed

Rieke V, Butts Pauly K (2008) MR thermometry. J Magn Reson Imaging 27:376–390CrossRefPubMed

10.

Vogl TJ, Lehnert T, Eichler K, Proschek D, Floter J, Mack MG (2007) Adrenal metastases: CT-guided and MR-thermometry-controlled laser-induced interstitial thermotherapy. Eur Radiol 17:2020–2027CrossRefPubMed

11.

Streitparth F, Gebauer B, Melcher I et al (2009) MR-guided laser ablation of osteoid osteoma in an open high-field system (1.0 T). Cardiovasc Interv Radiol 32:320–325CrossRef

12.

Streitparth F, Walter T, Wonneberger U et al (2010) Image-guided spinal injection procedures in open high-field MRI with vertical field orientation: feasibility and technical features. Eur Radiol 20:395–403CrossRefPubMed

13.

Gossmann A, Bangard C, Warm M, Schmutzler RK, Mallmann P, Lackner KJ (2008) Real-time MR-guided wire localization of breast lesions by using an open 1.0-T imager: initial experience. Radiology 247:535–542CrossRefPubMed

14.

Chopra SS, Rump J, Schmidt SC et al (2009) Imaging sequences for intraoperative MR-guided laparoscopic liver resection in 1.0-T high field open MRI. Eur Radiol 19:2191–2196CrossRefPubMed

15.

Kettenbach J, Silverman SG, Hata N et al (1998) Monitoring and visualization techniques for MR-guided laser ablations in an open MR system. J Magn Reson Imaging 8:933–943CrossRefPubMed

16.

de Senneville BD, Mougenot C, Quesson B, Dragonu I, Grenier N, Moonen CT (2007) MR thermometry for monitoring tumor ablation. Eur Radiol 17:2401–2410CrossRefPubMed

17.

Neumann RA, Knobler RM, Leonhartsberger H, Bohler-Sommeregger K, Gebhart W (1991) Histochemical evaluation of the coagulation depth after argon laser impact on a port-wine stain. Lasers Surg Med 11:606–615CrossRefPubMed

18.

Vogl TJ, Fieguth HG, Eichler K et al (2004) Laser-induced thermotherapy of lung metastases and primary lung tumors. Radiologe 44:693–699CrossRefPubMed

19.

Vogl TJ, Lehnert T, Wetter A, Mack MG, Wurster MG (2005) Interventional radiology in Carney triad. Eur Radiol 15:833–837CrossRefPubMed

20.

Vogl TJ, Mack MG, Muller P et al (1995) Recurrent nasopharyngeal tumors: preliminary clinical results with interventional MR imaging—controlled laser-induced thermotherapy. Radiology 196:725–733PubMed

21.

Vogl TJ, Mack MG, Muller PK, Straub R, Engelmann K, Eichler K (1999) Interventional MR: interstitial therapy. Eur Radiol 9:1479–1487CrossRefPubMed

22.

Vogl TJ, Muller PK, Hammerstingl R et al (1995) Malignant liver tumors treated with MR imaging-guided laser-induced thermotherapy: technique and prospective results. Radiology 196:257–265PubMed

23.

Vogl TJ, Muller PK, Mack MG, Straub R, Engelmann K, Neuhaus P (1999) Liver metastases: interventional therapeutic techniques and results, state of the art. Eur Radiol 9:675–684CrossRefPubMed

24.

Vogl TJ, Straub R, Eichler K, Sollner O, Mack MG (2004) Colorectal carcinoma metastases in liver: laser-induced interstitial thermotherapy—local tumor control rate and survival data. Radiology 230:450–458CrossRefPubMed

25.

Vogl TJ, Straub R, Zangos S, Mack MG, Eichler K (2004) MR-guided laser-induced thermotherapy (LITT) of liver tumours: experimental and clinical data. Int J Hyperthermia 20:713–724CrossRefPubMed

26.

Kahn T, Harth T, Kiwit JC, Schwarzmaier HJ, Wald C, Modder U (1998) In-vivo MRI thermometry using a phase-sensitive sequence: preliminary experience during MRI-guided laser-induced interstitial thermotherapy of brain tumors. J Magn Reson Imaging 8:160–164CrossRefPubMed

27.

Puls R, Stroszczynski C, Rosenberg C et al (2007) Three-dimensional gradient-echo imaging for percutaneous MR-guided laser therapy of liver metastasis. J Magn Reson Imaging 25:1174–1178CrossRefPubMed

28.

Seror O, Lepetit-Coiffe M, Le Bail B et al (2008) Real time monitoring of radiofrequency ablation based on MR thermometry and thermal dose in the pig liver in-vivo. Eur Radiol 18:408–416CrossRefPubMed

29.

Gaffke G, Gebauer B, Knollmann FD et al (2006) Use of semiflexible applicators for radiofrequency ablation of liver tumors. Cardiovasc Interv Radiol 29:270–275CrossRef

30.

Pereira PL, Trubenbach J, Schenk M et al (2004) Radiofrequency ablation: in-vivo comparison of four commercially available devices in pig livers. Radiology 232:482–490CrossRefPubMed

Titel: Laser-induced thermotherapy (LITT)—evaluation of a miniaturised applicator and implementation in a 1.0-T high-field open MRI applying a porcine liver model
verfasst von: Florian Streitparth
Gesine Knobloch
Dirk Balmert
Sascha Chopra
J. Rump
Uta Wonneberger
Carsten Philipp
Bernd Hamm
Ulf Teichgräber
Publikationsdatum: 01.11.2010
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 11/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-010-1831-6

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Laser-induced thermotherapy (LITT)—evaluation of a miniaturised applicator and implementation in a 1.0-T high-field open MRI applying a porcine liver model

Abstract

Objective:

Methods:

Results:

Conclusion:

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