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Erschienen in: European Radiology 1/2011

01.01.2011 | Cardiac

Diffusion-weighted echo planar imaging in patients with recent myocardial infarction

verfasst von: Jean-François Deux, Mezri Maatouk, Alexandre Vignaud, Alain Luciani, Grégory Lenczner, Julie Mayer, Pascal Lim, Jean-Luc Dubois-Randé, Hicham Kobeiter, Alain Rahmouni

Erschienen in: European Radiology | Ausgabe 1/2011

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Abstract

Objective

To evaluate a diffusion-weighted (DW) black blood MR sequence for the detection of myocardium signal abnormalities in patients with recent myocardial infarction (MI).

Methods

A DW black blood EPI sequence was acquired at 1.5 T in 12 patients with recent MI. One slice per patient was acquired with b = 0 and b = 50 s/mm2. A standard short tau inversion recovery (STIR) T2-weighted sequence was acquired at the same level. Viability was assessed with delayed-enhancement sequences. Images were analyzed qualitatively and quantitatively. A non parametric Wilcoxon test was used for statistical analysis, with a significance level of P < .05.

Results

The mean quality of blood suppression was higher on DW EPI images than on STIR T2-weighted images (3.9 ± 0.3 and 3.0 ± 0.7, respectively; P = 0.01). Myocardial high signal areas were detected in respectively 100% (12/12) and 67% (8/12) of the patients on DW EPI and STIR T2-weighted images. The four patients (33%) with false-negative STIR T2 findings all had high signal areas on DW EPI images corresponding to the location of the MI on the delayed-enhanced images.

Conclusion

DW EPI sequences are a feasible alternative to standard STIR T2-weighted sequences for detecting myocardium high signal areas in patients with recent MI.
Literatur
1.
Zurück zum Zitat Abdel-Aty H (2009) Myocardial edema imaging of the area at risk in acute myocardial infarction: seeing through water. JACC Cardiovasc Imaging 2:832–834CrossRefPubMed Abdel-Aty H (2009) Myocardial edema imaging of the area at risk in acute myocardial infarction: seeing through water. JACC Cardiovasc Imaging 2:832–834CrossRefPubMed
2.
Zurück zum Zitat Friedrich MG (2008) Tissue characterization of acute myocardial infarction and myocarditis by cardiac magnetic resonance. JACC Cardiovasc Imaging 1:652–662CrossRefPubMed Friedrich MG (2008) Tissue characterization of acute myocardial infarction and myocarditis by cardiac magnetic resonance. JACC Cardiovasc Imaging 1:652–662CrossRefPubMed
3.
Zurück zum Zitat Friedrich MG (2009) A closer look on the battlefield: the salvaged area at risk as an outcome marker for myocardial reperfusion. JACC Cardiovasc Imaging 2:577–579CrossRefPubMed Friedrich MG (2009) A closer look on the battlefield: the salvaged area at risk as an outcome marker for myocardial reperfusion. JACC Cardiovasc Imaging 2:577–579CrossRefPubMed
4.
Zurück zum Zitat Abdel-Aty H, Cocker M, Meek C, Tyberg JV, Friedrich MG (2009) Edema as a very early marker for acute myocardial ischemia: a cardiovascular magnetic resonance study. J Am Coll Cardiol 53:1194–1201CrossRefPubMed Abdel-Aty H, Cocker M, Meek C, Tyberg JV, Friedrich MG (2009) Edema as a very early marker for acute myocardial ischemia: a cardiovascular magnetic resonance study. J Am Coll Cardiol 53:1194–1201CrossRefPubMed
5.
Zurück zum Zitat Abdel-Aty H, Zagrosek A, Schulz-Menger J, Taylor AJ, Messroghli D, Kumar A, Gross M, Dietz R, Friedrich MG (2004) Delayed enhancement and T2-weighted cardiovascular magnetic resonance imaging differentiate acute from chronic myocardial infarction. Circulation 109:2411–2416CrossRefPubMed Abdel-Aty H, Zagrosek A, Schulz-Menger J, Taylor AJ, Messroghli D, Kumar A, Gross M, Dietz R, Friedrich MG (2004) Delayed enhancement and T2-weighted cardiovascular magnetic resonance imaging differentiate acute from chronic myocardial infarction. Circulation 109:2411–2416CrossRefPubMed
6.
Zurück zum Zitat Friedrich MG, Abdel-Aty H, Taylor A, Schulz-Menger J, Messroghli D, Dietz R (2008) The salvaged area at risk in reperfused acute myocardial infarction as visualized by cardiovascular magnetic resonance. J Am Coll Cardiol 51:1581–1587CrossRefPubMed Friedrich MG, Abdel-Aty H, Taylor A, Schulz-Menger J, Messroghli D, Dietz R (2008) The salvaged area at risk in reperfused acute myocardial infarction as visualized by cardiovascular magnetic resonance. J Am Coll Cardiol 51:1581–1587CrossRefPubMed
7.
Zurück zum Zitat Aletras AH, Tilak GS, Natanzon A, Hsu LY, Gonzalez FM, Hoyt RFJ, Arai AE (2006) Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations. Circulation 113:1865–1870CrossRefPubMed Aletras AH, Tilak GS, Natanzon A, Hsu LY, Gonzalez FM, Hoyt RFJ, Arai AE (2006) Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations. Circulation 113:1865–1870CrossRefPubMed
8.
Zurück zum Zitat Edwards NC, Routledge H, Steeds RP (2009) T2-weighted magnetic resonance imaging to assess myocardial oedema in ischaemic heart disease. Heart 95:1357–1361CrossRefPubMed Edwards NC, Routledge H, Steeds RP (2009) T2-weighted magnetic resonance imaging to assess myocardial oedema in ischaemic heart disease. Heart 95:1357–1361CrossRefPubMed
9.
Zurück zum Zitat Abdel-Aty H, Simonetti O, Friedrich MG (2007) T2-weighted cardiovascular magnetic resonance imaging. J Magn Reson Imaging 26:452–459CrossRefPubMed Abdel-Aty H, Simonetti O, Friedrich MG (2007) T2-weighted cardiovascular magnetic resonance imaging. J Magn Reson Imaging 26:452–459CrossRefPubMed
10.
Zurück zum Zitat Arai AE (2008) Using magnetic resonance imaging to characterize recent myocardial injury: utility in acute coronary syndrome and other clinical scenarios. Circulation 118:795–796CrossRefPubMed Arai AE (2008) Using magnetic resonance imaging to characterize recent myocardial injury: utility in acute coronary syndrome and other clinical scenarios. Circulation 118:795–796CrossRefPubMed
11.
Zurück zum Zitat Kellman P, Aletras AH, Mancini C, McVeigh ER, Arai AE (2007) T2-prepared SSFP improves diagnostic confidence in edema imaging in acute myocardial infarction compared to turbo spin echo. Magn Reson Med 57:891–897CrossRefPubMed Kellman P, Aletras AH, Mancini C, McVeigh ER, Arai AE (2007) T2-prepared SSFP improves diagnostic confidence in edema imaging in acute myocardial infarction compared to turbo spin echo. Magn Reson Med 57:891–897CrossRefPubMed
12.
Zurück zum Zitat Simonetti OP, Finn JP, White RD, Laub G, Henry DA (1996) “Black blood” T2-weighted inversion-recovery MR imaging of the heart. Radiology 199:49–57PubMed Simonetti OP, Finn JP, White RD, Laub G, Henry DA (1996) “Black blood” T2-weighted inversion-recovery MR imaging of the heart. Radiology 199:49–57PubMed
13.
Zurück zum Zitat Bornstedt A, Bernhardt P, Hombach V, Kamenz J, Spiess J, Subgang A, Rasche V (2008) Local excitation black blood imaging at 3T: application to the carotid artery wall. Magn Reson Med 59:1207–1211CrossRefPubMed Bornstedt A, Bernhardt P, Hombach V, Kamenz J, Spiess J, Subgang A, Rasche V (2008) Local excitation black blood imaging at 3T: application to the carotid artery wall. Magn Reson Med 59:1207–1211CrossRefPubMed
14.
Zurück zum Zitat Koktzoglou I, Chung YC, Carroll TJ, Simonetti OP, Morasch MD, Li D (2007) Three-dimensional black-blood MR imaging of carotid arteries with segmented steady-state free precession: initial experience. Radiology 243:220–228CrossRefPubMed Koktzoglou I, Chung YC, Carroll TJ, Simonetti OP, Morasch MD, Li D (2007) Three-dimensional black-blood MR imaging of carotid arteries with segmented steady-state free precession: initial experience. Radiology 243:220–228CrossRefPubMed
15.
Zurück zum Zitat Koktzoglou I, Li D (2007) Diffusion-prepared segmented steady-state free precession: application to 3D black-blood cardiovascular magnetic resonance of the thoracic aorta and carotid artery walls. J Cardiovasc Magn Reson 9:33–42CrossRefPubMed Koktzoglou I, Li D (2007) Diffusion-prepared segmented steady-state free precession: application to 3D black-blood cardiovascular magnetic resonance of the thoracic aorta and carotid artery walls. J Cardiovasc Magn Reson 9:33–42CrossRefPubMed
16.
Zurück zum Zitat Nguyen TD, de Rochefort L, Spincemaille P, Cham MD, Weinsaft JW, Prince MR, Wang Y (2008) Effective motion-sensitizing magnetization preparation for black blood magnetic resonance imaging of the heart. J Magn Reson Imaging 28:1092–1100CrossRefPubMed Nguyen TD, de Rochefort L, Spincemaille P, Cham MD, Weinsaft JW, Prince MR, Wang Y (2008) Effective motion-sensitizing magnetization preparation for black blood magnetic resonance imaging of the heart. J Magn Reson Imaging 28:1092–1100CrossRefPubMed
17.
Zurück zum Zitat Lauenstein TC, Sharma P, Hughes T, Heberlein K, Tudorascu D, Martin DR (2008) Evaluation of optimized inversion-recovery fat-suppression techniques for T2-weighted abdominal MR imaging. J Magn Reson Imaging 27:1448–1454CrossRefPubMed Lauenstein TC, Sharma P, Hughes T, Heberlein K, Tudorascu D, Martin DR (2008) Evaluation of optimized inversion-recovery fat-suppression techniques for T2-weighted abdominal MR imaging. J Magn Reson Imaging 27:1448–1454CrossRefPubMed
18.
Zurück zum Zitat Haacke M, Brown W, Thompson M, Venkatesan R (1999) Magnetic resonance imaging. Physical principles and sequence design. Chapter 15: Signal contrast and noise. John Wiley and Sons, New York, p 347 Haacke M, Brown W, Thompson M, Venkatesan R (1999) Magnetic resonance imaging. Physical principles and sequence design. Chapter 15: Signal contrast and noise. John Wiley and Sons, New York, p 347
19.
Zurück zum Zitat Albers GW, Lansberg MG, Norbash AM, Tong DC, O’Brien MW, Woolfenden AR, Marks MP, Moseley ME (2000) Yield of diffusion-weighted MRI for detection of potentially relevant findings in stroke patients. Neurology 54:1562–1567PubMed Albers GW, Lansberg MG, Norbash AM, Tong DC, O’Brien MW, Woolfenden AR, Marks MP, Moseley ME (2000) Yield of diffusion-weighted MRI for detection of potentially relevant findings in stroke patients. Neurology 54:1562–1567PubMed
20.
Zurück zum Zitat Na DG, Thijs VN, Albers GW, Moseley ME, Marks MP (2004) Diffusion-weighted MR imaging in acute ischemia: value of apparent diffusion coefficient and signal intensity thresholds in predicting tissue at risk and final infarct size. AJNR Am J Neuroradiol 25:1331–1336PubMed Na DG, Thijs VN, Albers GW, Moseley ME, Marks MP (2004) Diffusion-weighted MR imaging in acute ischemia: value of apparent diffusion coefficient and signal intensity thresholds in predicting tissue at risk and final infarct size. AJNR Am J Neuroradiol 25:1331–1336PubMed
21.
Zurück zum Zitat Moseley ME, Kucharczyk J, Mintorovitch J, Cohen Y, Kurhanewicz J, Derugin N, Asgari H, Norman D (1990) Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR Am J Neuroradiol 11:423–429PubMed Moseley ME, Kucharczyk J, Mintorovitch J, Cohen Y, Kurhanewicz J, Derugin N, Asgari H, Norman D (1990) Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR Am J Neuroradiol 11:423–429PubMed
22.
Zurück zum Zitat Le Bihan D (2008) Intravoxel incoherent motion perfusion MR imaging: a wake-up call. Radiology 249:748–752CrossRefPubMed Le Bihan D (2008) Intravoxel incoherent motion perfusion MR imaging: a wake-up call. Radiology 249:748–752CrossRefPubMed
23.
Zurück zum Zitat Le Bihan D, Breton E, Lallemand D, Aubin ML, Vignaud J, Laval-Jeantet M (1988) Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology 168:497–505PubMed Le Bihan D, Breton E, Lallemand D, Aubin ML, Vignaud J, Laval-Jeantet M (1988) Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology 168:497–505PubMed
24.
Zurück zum Zitat Neil JJ, Bosch CS, Ackerman JJ (1994) An evaluation of the sensitivity of the intravoxel incoherent motion (IVIM) method of blood flow measurement to changes in cerebral blood flow. Magn Reson Med 32:60–65CrossRefPubMed Neil JJ, Bosch CS, Ackerman JJ (1994) An evaluation of the sensitivity of the intravoxel incoherent motion (IVIM) method of blood flow measurement to changes in cerebral blood flow. Magn Reson Med 32:60–65CrossRefPubMed
25.
Zurück zum Zitat Pickens DRr, Jolgren DL, Lorenz CH, Creasy JL, Price RR (1992) Magnetic resonance perfusion/diffusion imaging of the excised dog kidney. Invest Radiol 27:287–292CrossRefPubMed Pickens DRr, Jolgren DL, Lorenz CH, Creasy JL, Price RR (1992) Magnetic resonance perfusion/diffusion imaging of the excised dog kidney. Invest Radiol 27:287–292CrossRefPubMed
26.
Zurück zum Zitat Luciani A, Vignaud A, Cavet M, Nhieu JT, Mallat A, Ruel L, Laurent A, Deux JF, Brugieres P, Rahmouni A (2008) Liver cirrhosis: intravoxel incoherent motion MR imaging–pilot study. Radiology 249:891–899CrossRefPubMed Luciani A, Vignaud A, Cavet M, Nhieu JT, Mallat A, Ruel L, Laurent A, Deux JF, Brugieres P, Rahmouni A (2008) Liver cirrhosis: intravoxel incoherent motion MR imaging–pilot study. Radiology 249:891–899CrossRefPubMed
27.
Zurück zum Zitat Callot V, Bennett E, Decking UK, Balaban RS, Wen H (2003) In vivo study of microcirculation in canine myocardium using the IVIM method. Magn Reson Med 50:531–540CrossRefPubMed Callot V, Bennett E, Decking UK, Balaban RS, Wen H (2003) In vivo study of microcirculation in canine myocardium using the IVIM method. Magn Reson Med 50:531–540CrossRefPubMed
28.
Zurück zum Zitat Vignaud A, Rodriguez I, Ennis DB, DeSilva R, Kellman P, Taylor J, Bennett E, Wen H (2006) Detection of myocardial capillary orientation with intravascular iron-oxide nanoparticles in spin-echo MRI. Magn Reson Med 55:725–730CrossRefPubMed Vignaud A, Rodriguez I, Ennis DB, DeSilva R, Kellman P, Taylor J, Bennett E, Wen H (2006) Detection of myocardial capillary orientation with intravascular iron-oxide nanoparticles in spin-echo MRI. Magn Reson Med 55:725–730CrossRefPubMed
29.
Zurück zum Zitat Poustchi-Amin M, Mirowitz SA, Brown JJ, McKinstry RC, Li T (2001) Principles and applications of echo-planar imaging: a review for the general radiologist. Radiographics 21:767–779PubMed Poustchi-Amin M, Mirowitz SA, Brown JJ, McKinstry RC, Li T (2001) Principles and applications of echo-planar imaging: a review for the general radiologist. Radiographics 21:767–779PubMed
30.
Zurück zum Zitat van den Bos IC, Hussain SM, Krestin GP, Wielopolski PA (2008) Liver imaging at 3.0T: diffusion-induced black-blood echo-planar imaging with large anatomic volumetric coverage as an alternative for specific absorption rate-intensive echo-train spin-echo sequences: feasibility study. Radiology 248:264–271CrossRefPubMed van den Bos IC, Hussain SM, Krestin GP, Wielopolski PA (2008) Liver imaging at 3.0T: diffusion-induced black-blood echo-planar imaging with large anatomic volumetric coverage as an alternative for specific absorption rate-intensive echo-train spin-echo sequences: feasibility study. Radiology 248:264–271CrossRefPubMed
31.
Zurück zum Zitat Reese TG, Weisskoff RM, Smith RN, Rosen BR, Dinsmore RE, Wedeen VJ (1995) Imaging myocardial fiber architecture in vivo with magnetic resonance. Magn Reson Med 34:786–791CrossRefPubMed Reese TG, Weisskoff RM, Smith RN, Rosen BR, Dinsmore RE, Wedeen VJ (1995) Imaging myocardial fiber architecture in vivo with magnetic resonance. Magn Reson Med 34:786–791CrossRefPubMed
Metadaten
Titel
Diffusion-weighted echo planar imaging in patients with recent myocardial infarction
verfasst von
Jean-François Deux
Mezri Maatouk
Alexandre Vignaud
Alain Luciani
Grégory Lenczner
Julie Mayer
Pascal Lim
Jean-Luc Dubois-Randé
Hicham Kobeiter
Alain Rahmouni
Publikationsdatum
01.01.2011
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 1/2011
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1912-6

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