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Erschienen in: European Radiology 2/2013

01.02.2013 | Contrast Media

Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Medium Safety Committee guidelines

verfasst von: Henrik S. Thomsen, Sameh K. Morcos, Torsten Almén, Marie-France Bellin, Michele Bertolotto, Georg Bongartz, Olivier Clement, Peter Leander, Gertraud Heinz-Peer, Peter Reimer, Fulvio Stacul, Aart van der Molen, Judith AW Webb

Erschienen in: European Radiology | Ausgabe 2/2013

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Abstract

Purpose

To update the guidelines of the Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) on nephrogenic systemic fibrosis and gadolinium-based contrast media.

Areas covered

Topics reviewed include the history, clinical features and prevalence of nephrogenic systemic fibrosis and the current understanding of its pathophysiology. The risk factors for NSF are discussed and prophylactic measures are recommended. The stability of the different gadolinium-based contrast media and the potential long-term effects of gadolinium in the body have also been reviewed.

Key Points

Clinical features, risk factors and prevention of nephrogenic systemic fibrosis are reviewed
Patients with GFR below 30 ml/min/1.73 m 2 have increased risk of developing NSF
Low stability gadolinium contrast media show the strongest association with NSF
Following guidelines regarding gadolinium contrast agents minimises the risk of NSF
Potential long-term harm from gadolinium accumulation in the body is discussed
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Metadaten
Titel
Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Medium Safety Committee guidelines
verfasst von
Henrik S. Thomsen
Sameh K. Morcos
Torsten Almén
Marie-France Bellin
Michele Bertolotto
Georg Bongartz
Olivier Clement
Peter Leander
Gertraud Heinz-Peer
Peter Reimer
Fulvio Stacul
Aart van der Molen
Judith AW Webb
Publikationsdatum
01.02.2013
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 2/2013
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-012-2597-9

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