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European Radiology

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01.04.2013 | Head and Neck

Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients

verfasst von: Hyun Kyung Lim, Jeong Hyun Lee, Eun Ju Ha, Jin Young Sung, Jae Kyun Kim, Jung Hwan Baek

Erschienen in: European Radiology | Ausgabe 4/2013

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Abstract

Objectives

To evaluate the clinical outcomes and safety of radiofrequency (RF) ablation for benign non-functioning thyroid nodules over a 4-year follow-up.

Methods

We evaluated 126 benign non-functioning thyroid nodules of 111 patients treated with RF ablation and followed-up more than 3 years. RF ablation was performed using the Cool-Tip RF system and an internally cooled electrode. Nodule volume and cosmetic and symptom scores were evaluated before treatment and during follow-up. Complications and factors related to efficacy were evaluated.

Results

The mean follow-up duration was 49.4 ± 13.6 months. Thyroid nodule volume decreased significantly, from 9.8 ± 8.5 ml before ablation to 0.9 ± 3.3 ml (P < 0.001) at final evaluation: a mean volume reduction of 93.4 ± 11.7 %. The mean cosmetic (P < 0.001) and symptom scores (P < 0.001) improved significantly. Factors related to efficacy were initial solidity and volume. The overall recurrence rate was 5.6 % (7/126). The overall complication rate was 3.6 % (4/111).

Conclusions

RF ablation was effective in shrinking benign thyroid nodules and in controlling nodule-related problems over a 4-year follow-up. There were no life-threatening complications or sequelae. Therefore, RF ablation can be used as a non-surgical treatment for patients with benign non-functioning thyroid nodules.

Key Points

• Radiofrequency (RF) ablation provides a non-surgical option for benign non-functioning thyroid nodules

• RF ablation reduced non-functioning thyroid nodular volume by 93.5 % after 49 months

• Initial solidity and volume influenced the efficacy of RF ablation

• Larger thyroid nodules required more treatment sessions to achieve appropriate volume reduction

• Complete treatment of the periphery of the nodule is important in preventing marginal regrowth

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Titel: Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients
verfasst von: Hyun Kyung Lim
Jeong Hyun Lee
Eun Ju Ha
Jin Young Sung
Jae Kyun Kim
Jung Hwan Baek
Publikationsdatum: 01.04.2013
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 4/2013
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-012-2671-3

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Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Neu im Fachgebiet Radiologie

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

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Studie bestätigt Potenzial von KI in der Radiologie

Update Radiologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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