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European Radiology

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01.10.2014 | Cardiac

Meta-analysis: diagnostic accuracy of coronary CT angiography with prospective ECG gating based on step-and-shoot, Flash and volume modes for detection of coronary artery disease

verfasst von: Linfeng Yang, Tao Zhou, Ruijie Zhang, Lin Xu, Zhaohui Peng, Juan Ding, Sen Wang, Min Li, Gang Sun

Erschienen in: European Radiology | Ausgabe 10/2014

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Abstract

Objectives

To investigate the diagnostic performance of coronary computed tomographic angiography (CCTA) with prospective electrocardiograph (ECG) gating based on step-and-shoot (SAS), Flash and volume imaging modes.

Methods

We searched the electronic databases PubMed for all published studies regarding CCTA. We used an exact binomial rendition of the bivariate mixed-effects regression model developed for synthesis of diagnostic data.

Results

A total of 21,852 segments, 4,851 vessels and 1,375 patients were identified using database searches. Patient-level pooled sensitivity was 0.99 (95 % confidence interval [CI], 0.98–1.00); specificity was 0.88 (CI, 0.85–0.91). The results showed that the sensitivity and specificity for detection of significant stenosis did not differ in the three protocols (P = 0.24). No heterogeneity was found at the patient level for sensitivity (Q = 26.23; P = 0.12; I ² = 27.56 % [CI, 0.00-67.02 %]) and specificity (Q = 19.54; P = 0.42; I ² = 2.78 % [CI, 0.00-66.26 %]).

Conclusions

CCTA with prospective ECG gating has similar high diagnostic value to rule out CAD in all three presented modes.

Key Points

• The accuracy of CCTA with different prospective ECG gating is similar

• CCTA with prospective ECG gating is effective to exclude coronary artery disease

• The radiation dose of volume mode increases with higher heart rate

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Titel: Meta-analysis: diagnostic accuracy of coronary CT angiography with prospective ECG gating based on step-and-shoot, Flash and volume modes for detection of coronary artery disease
verfasst von: Linfeng Yang
Tao Zhou
Ruijie Zhang
Lin Xu
Zhaohui Peng
Juan Ding
Sen Wang
Min Li
Gang Sun
Publikationsdatum: 01.10.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 10/2014
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-014-3221-y

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Meta-analysis: diagnostic accuracy of coronary CT angiography with prospective ECG gating based on step-and-shoot, Flash and volume modes for detection of coronary artery disease

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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