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Erschienen in: European Radiology 4/2015

01.04.2015 | Neuro

3D MR Sequence Capable of Simultaneous Image Acquisitions with and without Blood Vessel Suppression: Utility in Diagnosing Brain Metastases

verfasst von: Kazufumi Kikuchi, Akio Hiwatashi, Osamu Togao, Koji Yamashita, Masami Yoneyama, Makoto Obara, Junji Kishimoto, Takashi Yoshiura, Hiroshi Honda

Erschienen in: European Radiology | Ausgabe 4/2015

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Abstract

Objective

Volume isotropic simultaneous interleaved bright- and black-blood examination (VISIBLE) is a recently developed 3D MR sequence that provides simultaneous acquisitions of images with blood vessel suppression (Black) and images without it (Bright). Our purpose was to evaluate the usefulness of VISIBLE in detecting brain metastases.

Methods

This prospective study included patients with suspected brain metastasis imaged with both VISIBLE and MPRAGE. From a data set, we compared the number of visualized blood vessels and the lesion-to-normal contrast-to-noise ratio (CNR) in 60 patients. We also performed an observer test to compare their diagnostic performance with VISIBLE, MPRAGE and only Black in 34 patients. Diagnostic performance was evaluated using a figure of merit (FOM), sensitivity, false-positive results per case (FPs/case) and reading time.

Results

The number of vessels was significantly fewer in Black compared to MPRAGE and Bright (P < 0.0001). CNR was significantly higher with both Black and Bright than with MPRAGE (P < 0.005). In the observer test, significantly higher sensitivity (P < 0.0001) and FOM (P < 0.0001), significantly shorter reading time (P = 0.0001) and similar FPs/case were achieved with VISIBLE compared to MPRAGE. Compared to only Black, VISIBLE resulted in comparable sensitivity, but significantly fewer FPs/case (P = 0.0008).

Conclusion

VISIBLE can improve radiologists’ diagnostic performance for brain metastasis.

Key Points

VISIBLE can achieve higher sensitivity and shorter reading time than MPRAGE.
VISIBLE can achieve lower false-positive rates than blood vessel suppressed images.
Compared to MPRAGE, VISIBLE can improve diagnostic performance for brain metastasis.
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Metadaten
Titel
3D MR Sequence Capable of Simultaneous Image Acquisitions with and without Blood Vessel Suppression: Utility in Diagnosing Brain Metastases
verfasst von
Kazufumi Kikuchi
Akio Hiwatashi
Osamu Togao
Koji Yamashita
Masami Yoneyama
Makoto Obara
Junji Kishimoto
Takashi Yoshiura
Hiroshi Honda
Publikationsdatum
01.04.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 4/2015
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3496-z

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