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Erschienen in: World Journal of Urology 4/2011

01.08.2011 | Topic Paper

Tm:YAG laser en bloc mucosectomy for accurate staging of primary bladder cancer: early experience

verfasst von: Mathias Wolters, Mario W. Kramer, Jan U. Becker, Matthias Christgen, Udo Nagele, Florian Imkamp, Martin Burchardt, Axel S. Merseburger, Markus A. Kuczyk, Thorsten Bach, Andreas J. Gross, Thomas R. W. Herrmann

Erschienen in: World Journal of Urology | Ausgabe 4/2011

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Abstract

Introduction

Exact pathological staging of bladder cancer is crucial for determination of further treatment. One limiting factor is the surgical ‘incise and scatter’ technique that might contribute to tumour recurrence. En bloc resection techniques are en emerging issue. We present initial results with Thulium:YAG (Tm:YAG) en bloc resection of bladder tumours for treatment and accurate staging of solitary transitional cell carcinoma of the bladder.

Materials and methods

From June through October 2010, six patients were treated by TmLRBT (Thulium laser resection of bladder tumour). Inclusion criteria were solitary lesions, treatment naive patients and tumour localisation of the lower bladder wall and trigonum. En bloc resection was applied on all of the tumours. Two cold-cut biopsies from the tumour base were extracted. On five of the six patients, a re-resection was performed after 6 weeks.

Results

Pathological evaluation revealed 1 patient with pTa G1, 2 patients with pTa G2 and 3 patients with pT1 G3. All of the resected specimens provided detrusor muscle, and all biopsies were positive for muscle cells. No intra-, peri- or post-operative complications were observed. Bladder irrigation was mandatory in only 50% of the patients. All patients were negative for residual TCC in re-resection 6 weeks after initial treatment.

Conclusion

TmLRBT has been proven safe and effective for both, treatment and pathological staging of primary TCC of the bladder. Tm:YAG en bloc resection therefore could be an appropriate tool for accurate staging with possibly lower scattering potential for the assessment and treatment of patients with TCC.
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Metadaten
Titel
Tm:YAG laser en bloc mucosectomy for accurate staging of primary bladder cancer: early experience
verfasst von
Mathias Wolters
Mario W. Kramer
Jan U. Becker
Matthias Christgen
Udo Nagele
Florian Imkamp
Martin Burchardt
Axel S. Merseburger
Markus A. Kuczyk
Thorsten Bach
Andreas J. Gross
Thomas R. W. Herrmann
Publikationsdatum
01.08.2011
Verlag
Springer-Verlag
Erschienen in
World Journal of Urology / Ausgabe 4/2011
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-011-0686-z

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